Larry A. Sklar

Center for Molecular Discovery, University of New Mexico Health Sciences Center

Affiliated withUniversity of New Mexico Health Sciences Center University of New Mexico

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2024

Other Publications

Article	Year
Solubilization and display of G protein-coupled receptors on beads for real-time fluorescence and flow cytometric analysis. BioTechniques\| PubMed ID: 10818705	2000
Flow cytometric analysis of ligand-receptor interactions and molecular assemblies. Annual review of biophysics and biomolecular structure\| PubMed ID: 11988464	2002
Flow cytometry for drug discovery, receptor pharmacology and high-throughput screening. Current opinion in pharmacology\| PubMed ID: 17652026	2007
Characterization of a Cdc42 protein inhibitor and its use as a molecular probe. The Journal of biological chemistry\| PubMed ID: 23382385	2013
Fluorescent substrates for flow cytometric evaluation of efflux inhibition in ABCB1, ABCC1, and ABCG2 transporters. Analytical biochemistry\| PubMed ID: 23470221	2013
The University of New Mexico Center for Molecular Discovery. Combinatorial chemistry & high throughput screening\| PubMed ID: 24409953	2014
Identification of isoxsuprine hydrochloride as a neuroprotectant in ischemic stroke through cell-based high-throughput screening. PloS one\| PubMed ID: 24804769	2014
A high throughput flow cytometric assay platform targeting transporter inhibition. Drug discovery today. Technologies\| PubMed ID: 25027381	2014
FRET detection of lymphocyte function-associated antigen-1 conformational extension. Molecular biology of the cell\| PubMed ID: 25378583	2015
Discovery of Small-Molecule Nonfluorescent Inhibitors of Fluorogen-Fluorogen Activating Protein Binding Pair. Journal of biomolecular screening\| PubMed ID: 26442911	2016
Novel Activities of Select NSAID R-Enantiomers against Rac1 and Cdc42 GTPases. PloS one\| PubMed ID: 26558612	2015
Cyclic AMP efflux inhibitors as potential therapeutic agents for leukemia. Oncotarget\| PubMed ID: 27129155	2016
A High-Throughput Flow Cytometry Assay for Identification of Inhibitors of 3',5'-Cyclic Adenosine Monophosphate Efflux. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 27316999	2016
High-Throughput Screening Approach for Identifying Compounds That Inhibit Nonhomologous End Joining. SLAS discovery : advancing life sciences R & D\| PubMed ID: 29232168	2018
Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations. Autophagy\| PubMed ID: 29938597	2018
Clioquinol: To harm or heal. Pharmacology & therapeutics\| PubMed ID: 30898518	2019
Autophagy, Inflammation, and Metabolism (AIM) Center in its second year. Autophagy\| PubMed ID: 31234750	2019
A Selective Ligand for Estrogen Receptor Proteins Discriminates Rapid and Genomic Signaling. Cell chemical biology\| PubMed ID: 31706983	2019
Dynamic Imaging of LDH Inhibition in Tumors Reveals Rapid In Vivo Metabolic Rewiring and Vulnerability to Combination Therapy. Cell reports\| PubMed ID: 32049011	2020
Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties. Journal of medicinal chemistry\| PubMed ID: 32902275	2020
RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia. The Journal of clinical investigation\| PubMed ID: 33555272	2021
A phenotypic screen for compounds that reverse cAMP-mediated suppression of T cell functions. SLAS discovery : advancing life sciences R & D\| PubMed ID: 35385793	2022