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Immunology and Infection
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Screening of β2 Integrin Activation Inhibitors in Human Neutrophils
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Development of a Method for Identifying Small Molecular Antagonists of β2 Integrin Activation (Video) | JoVE
JoVE Journal
Immunology and Infection
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JoVE Journal Immunology and Infection
A Flow Cytometry-Based High-Throughput Technique for Screening Integrin-Inhibitory Drugs

Development of a Method for Identifying Small Molecular Antagonists of β2 Integrin Activation (Video) | JoVE

Screening of β2 Integrin Activation Inhibitors in Human Neutrophils

DOI:
10.3791/64401-v

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00:45 min

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February 02, 2024

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, , , ,
1Department of Immunology, School of Medicine,UConn Health, 2Center for Molecular Discovery,University of New Mexico Health Sciences Center, 3Comprehensive Cancer Center,University of New Mexico Health Sciences Center, 4Department of Pathology,University of New Mexico Health Sciences Center, 5Autophagy, Inflammation, & Metabolism (AIM) Center,University of New Mexico

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Keywords: Flow CytometryHigh-throughput ScreeningIntegrin InhibitorBeta-2 IntegrinNeutrophilAnti-inflammatoryConformational Change AntibodyFMLPGPCR

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