investigating-effect-different-types-exercise-on-upper-limb

Investigating the Effect of Different Types of Exercise on Upper Limb Functional Recovery in Patients with Right Hemisphere Damage Based on fNIRS

To investigate the effects of functional occupational therapy (FOT) combined with different types of exercise on upper limb motor function recovery and ...

effect-eye-tracking-technology-based-visual-scanning-training-on

Effect of Eye-Tracking Technology-Based Visual Scanning Training on Unilateral Spatial Neglect after Stroke

This study aimed to explore the effect of eye-tracking technology-based visual scanning training on recovery from unilateral spatial neglect after stroke. ...

China Rehabilitation Research Center

Capital Medical University

[Purpose] The purpose of this study was to compare prefrontal activations during an added-purpose task with those during a single-purpose task using functional near-infrared spectroscopy. [Subjects] Six healthy right-handed adults were included in this study. [Methods] The participants were instructed to complete both added-purpose and single-purpose activities separately with each hand. The near-infrared spectroscopy probes were placed on the scalp overlying the prefrontal cortex, according to the International 10-20 system (Fz). Changes in the oxygenated hemoglobin and deoxygenated hemoglobin concentrations in the prefrontal cortex were measured during performance of the activities. We then compared the number of activation channels with significant increase in oxygenated hemoglobin, during added-purpose activity to single-purpose activity using both hands separately. [Results] A greater number of widespread activations were observed in the prefrontal cortex during the added-purpose task than during the single-purpose task. These results were noted with both right and left hands. [Conclusion] According to our findings, added-purpose activity can bring about more activation in the prefrontal cortex, which may provide occupational therapists with effective guides in therapeutic practice.

Comparison of cortical activation in an upper limb added-purpose task versus a single-purpose task: a near-infrared spectroscopy study.

Depression is a common but easily misdiagnosed disease when using a self-assessment scale. Electroencephalograms (EEGs) provide an important reference and objective basis for the identification and diagnosis of depression. In order to improve the accuracy of the diagnosis of depression by using mainstream algorithms, a high-performance hybrid neural network depression detection method is proposed in this paper combined with deep learning technology. Firstly, a concatenating one-dimensional convolutional neural network (1D-CNN) and gated recurrent unit (GRU) are employed to extract the local features and to determine the global features of the EEG signal. Secondly, the attention mechanism is introduced to form the hybrid neural network. The attention mechanism assigns different weights to the multi-dimensional features extracted by the network, so as to screen out more representative features, which can reduce the computational complexity of the network and save the training time of the model while ensuring high precision. Moreover, dropout is applied to accelerate network training and address the over-fitting problem. Experiments reveal that the 1D-CNN-GRU-ATTN model has more effectiveness and a better generalization ability compared with traditional algorithms. The accuracy of the proposed method in this paper reaches 99.33% in a public dataset and 97.98% in a private dataset, respectively.

A Depression Diagnosis Method Based on the Hybrid Neural Network and Attention Mechanism.

Robot-assisted neuro-rehabilitation therapy plays a central role in upper extremity recovery of stroke. However, the efficacy of robotic training on the upper extremity is not yet well defined, and little attention has been devoted to its potential effect on the lower extremity. The aim of this study was to compare the efficacy of robot-assisted training and therapist-mediated enhanced upper extremity therapy on the upper and lower extremities.

Comparative Effectiveness of Robot-Assisted Training Versus Enhanced Upper Extremity Therapy on Upper and Lower Extremity for Stroke Survivors: A Multicentre Randomized Controlled Trial.

Motor dysfunction in the upper extremities after stroke prohibits people with stroke from being independent in daily living. The application of fNIRS to explore brain activity under rehabilitation intervention is a research focus on neurorehabilitation.

A study of dynamic hand orthosis combined with unilateral task-oriented training in subacute stroke: A functional near-infrared spectroscopy case series.

The purpose of the study was to investigate the time course difference of relative changes in oxygenated hemoglobin (Oxy-Hb) concentration in the prefrontal cortex (PFC) between controls and patients with post-stroke cognitive impairment (PSCI) who had right hemisphere damage (RHD) using the continuous performance test (CPT) and functional near-infrared spectroscopy (fNIRS) technology. The study aimed to evaluate the feasibility of CPT in the diagnosis and evaluation of PSCI with RHD.

The continuous performance test aids the diagnosis of post-stroke cognitive impairment in patients with right hemisphere damage.

The mirror neuron system (MNS) plays a key role in the neural mechanism underlying motor learning and neural plasticity. Action observation (AO), action execution (AE), and a combination of both, known as action imitation (AI), are the most commonly used rehabilitation strategies based on MNS. It is possible to enhance the cortical activation area and amplitude by combining traditional neuromuscular electrical stimulation (NMES) with other top-down and active rehabilitation strategies based on the MNS theory.

Cortical activation of neuromuscular electrical stimulation synchronized mirror neuron rehabilitation strategies: an fNIRS study.

Treating prolonged disorders of consciousness (pDoC) is challenging. Thus, accurate assessment of residual consciousness in patients with pDoC is important for the management and recovery of patients. Functional near-infrared spectroscopy (fNIRS) can be used to detect brain activity through changes of oxygenated hemoglobin/deoxygenated hemoglobin (HbO/HbR) concentrations changes and has recently gained increasing attention for its potential applications in assessing residual consciousness. However, the number of fNIRS studies assessing residual awareness in patients with pDoC is still limited. In this study, fNIRS was used to evaluate the brain function in 18 patients with pDoC, including 14 vegetative states (VS) and 4 minimally conscious states (MCS), and 15 healthy controls (HC). All participants accepted two types of external stimuli, i.e., active stimulation (motor imagery, MI) and passive stimulation (subject's own name, SON). The results showed that the mean concentrations of HbO/HbR in the prefrontal cortex of the HC during the passive stimulation were significantly lower than those of the active stimulation, and the fitting slope was high. However, the hemodynamic responses of the patients with pDoC were opposite to those of the HC. Additionally, the mean concentrations of HbO/HbR increased as the level of consciousness decreased during passive stimulation. Our findings suggest that the residual level of consciousness in pDoC patients can be assessed by measuring brain responses to different stimulations using fNIRS. The present study further demonstrates the feasibility and reliability of fNIRS in assessing residual consciousness in patients with pDoC, providing a basis for its expanded clinical application.

A functional near-infrared spectroscopy study on hemodynamic changes of patients with prolonged disorders of consciousness responding to different auditory stimuli.

Remote limb ischemic preconditioning alleviated spinal cord injury through inhibiting proinflammatory immune response and promoting the survival of spinal neurons.

Observation, execution, and imitation of target actions based on mirror neuron network (MNN) have become common physiotherapy strategies. Electrical stimulation (ES) is a common intervention to improve muscle strength and motor control in rehabilitation treatments. It is possible to enhance MNN's activation by combining motor execution (ME) and motor imitation (MI) with ES simultaneously. This study aims to reveal whether ES could impact cortical activation during ME and MI.

Effects of Electrical Stimulation on Activation of Mirror Neuron Network in Healthy Adults during Motor Execution and Imitation: An fNIRS Study.

This study aimed to analyze recent research and emerging trends in transcranial magnetic stimulation (TMS) for stroke rehabilitation.

ArticleTotal : 2	Year
Publication title Cited by 1	2024
Publication title	2025

Article	Year
Comparison of cortical activation in an upper limb added-purpose task versus a single-purpose task: a near-infrared spectroscopy study. Journal of physical therapy science\| PubMed ID: 26834375	2015
A Depression Diagnosis Method Based on the Hybrid Neural Network and Attention Mechanism. Brain sciences\| PubMed ID: 35884641	2022
Comparative Effectiveness of Robot-Assisted Training Versus Enhanced Upper Extremity Therapy on Upper and Lower Extremity for Stroke Survivors: A Multicentre Randomized Controlled Trial. Journal of rehabilitation medicine\| PubMed ID: 35892319	2022
A study of dynamic hand orthosis combined with unilateral task-oriented training in subacute stroke: A functional near-infrared spectroscopy case series. Frontiers in neurology\| PubMed ID: 36034313	2022
The continuous performance test aids the diagnosis of post-stroke cognitive impairment in patients with right hemisphere damage. Frontiers in neurology\| PubMed ID: 37456654	2023
Cortical activation of neuromuscular electrical stimulation synchronized mirror neuron rehabilitation strategies: an fNIRS study. Frontiers in neurology\| PubMed ID: 37602262	2023
A functional near-infrared spectroscopy study on hemodynamic changes of patients with prolonged disorders of consciousness responding to different auditory stimuli. BMC neurology\| PubMed ID: 37353754	2023
Remote limb ischemic preconditioning alleviated spinal cord injury through inhibiting proinflammatory immune response and promoting the survival of spinal neurons. Spinal cord\| PubMed ID: 39154149	2024
Effects of Electrical Stimulation on Activation of Mirror Neuron Network in Healthy Adults during Motor Execution and Imitation: An fNIRS Study. Journal of integrative neuroscience\| PubMed ID: 39862008	2025
Research on transcranial magnetic stimulation for stroke rehabilitation: a visual analysis based on CiteSpace. European journal of medical research\| PubMed ID: 40616172	2025

FuBiao Huang

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