Jiahuai Han

State Key Laboratory of Cellular Stress Biology, Xiamen University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
Organelle-Directed Metabolic Glycan Labeling and Optical Tracking of Dysfunctional Lysosomes Thereof. Analytical chemistry\| PubMed ID: 33140967	2020
Axin utilizes distinct regions for competitive MEKK1 and MEKK4 binding and JNK activation. The Journal of biological chemistry\| PubMed ID: 12878610	2003
Beta-actin is required for mitochondria clustering and ROS generation in TNF-induced, caspase-independent cell death. Journal of cell science\| PubMed ID: 15371523	2004
Axin stimulates p53 functions by activation of HIPK2 kinase through multimeric complex formation. The EMBO journal\| PubMed ID: 15526030	2004
Distinct roles of basal steady-state and induced H-ferritin in tumor necrosis factor-induced death in L929 cells. Molecular and cellular biology\| PubMed ID: 16024802	2005
Frequency and distribution of AP-1 sites in the human genome. DNA research : an international journal for rapid publication of reports on genes and genomes\| PubMed ID: 16303745	2005
Limiting inflammatory responses during activation of innate immunity. Nature immunology\| PubMed ID: 16369559	2005
Nod1-dependent control of tumor growth. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16446438	2006
Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia. The EMBO journal\| PubMed ID: 16601693	2006
Determinants that control the specific interactions between TAB1 and p38alpha. Molecular and cellular biology\| PubMed ID: 16648477	2006
Differential requirement of MKK4 and MKK7 in JNK activation by distinct scaffold proteins. FEBS letters\| PubMed ID: 17187786	2007
The pathways to tumor suppression via route p38. Trends in biochemical sciences\| PubMed ID: 17624785	2007
A beta-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by aida. Developmental cell\| PubMed ID: 17681137	2007
Adenine nucleotide (ADP/ATP) translocase 3 participates in the tumor necrosis factor induced apoptosis of MCF-7 cells. Molecular biology of the cell\| PubMed ID: 17855512	2007
Determinants that control the distinct subcellular localization of p38alpha-PRAK and p38beta-PRAK complexes. The Journal of biological chemistry\| PubMed ID: 18268017	2008
Impaired microRNA processing causes corpus luteum insufficiency and infertility in mice. The Journal of clinical investigation\| PubMed ID: 18398510	2008
TNF-alpha stimulation inhibits siRNA-mediated RNA interference through a mechanism involving poly-(A) tail stabilization. Biochimica et biophysica acta\| PubMed ID: 18423387	2008
[Construction of a novel gene therapy lentiviral vector for drug resistant selection and detection in vivo]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology\| PubMed ID: 18464610	2008
[Screening of highly effective siRNA sequence targeting to HIV-1 vif and the lentiviral-mediated antiviral research in vitro]. Bing du xue bao = Chinese journal of virology / [bian ji, Bing du xue bao bian ji wei yuan hui]\| PubMed ID: 18533339	2008
Inflammatory signaling and cellular senescence. Cellular signalling\| PubMed ID: 18992324	2009
p38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanisms. The Journal of biological chemistry\| PubMed ID: 19251701	2009
Poly(styrene-alt-maleic anhydride) derivatives as potent anti-HIV microbicide candidates. Bioorganic & medicinal chemistry letters\| PubMed ID: 19269820	2009
Multivalent mannose-displaying nanoparticles constructed from poly{styrene-co-[(maleic anhydride)-alt-styrene]}. Organic & biomolecular chemistry\| PubMed ID: 19421440	2009
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science (New York, N.Y.)\| PubMed ID: 19498109	2009
Axin determines cell fate by controlling the p53 activation threshold after DNA damage. Nature cell biology\| PubMed ID: 19731416	2009
Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade. The Journal of clinical investigation\| PubMed ID: 20038814	2010
Distinct effects of p38alpha deletion in myeloid lineage and gut epithelia in mouse models of inflammatory bowel disease. Gastroenterology\| PubMed ID: 20080092	2010
Specific regulation of noncanonical p38alpha activation by Hsp90-Cdc37 chaperone complex in cardiomyocyte. Circulation research\| PubMed ID: 20299663	2010
Receptor-interacting protein (RIP) kinase family. Cellular & molecular immunology\| PubMed ID: 20383176	2010
Epithelial p38alpha controls immune cell recruitment in the colonic mucosa. PLoS pathogens\| PubMed ID: 20532209	2010
Activation of p38 and determination of its activity. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 20811977	2010
The miR-17-92 cluster of microRNAs confers tumorigenicity by inhibiting oncogene-induced senescence. Cancer research\| PubMed ID: 20851997	2010
Participation of the p38 pathway in Drosophila host defense against pathogenic bacteria and fungi. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21076039	2010
Oxidation-induced intramolecular disulfide bond inactivates mitogen-activated protein kinase kinase 6 by inhibiting ATP binding. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21078955	2010
p38γ regulates UV-induced checkpoint signaling and repair of UV-induced DNA damage. Protein & cell\| PubMed ID: 21170151	2010
Multiple death pathways in TNF-treated fibroblasts: RIP3- and RIP1-dependent and independent routes. Cell research\| PubMed ID: 21200403	2011
MAPK signaling in inflammation-associated cancer development. Protein & cell\| PubMed ID: 21203968	2010
Inactivation of Rheb by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1. Nature cell biology\| PubMed ID: 21336308	2011
MLK4 has negative effect on TLR4 signaling. Cellular & molecular immunology\| PubMed ID: 21602844	2012
Phosphorylation of Raptor by p38beta participates in arsenite-induced mammalian target of rapamycin complex 1 (mTORC1) activation. The Journal of biological chemistry\| PubMed ID: 21757713	2011
Imaging of intracellular acidic compartments with a sensitive rhodamine based fluorogenic pH sensor. The Analyst\| PubMed ID: 21792437	2011
AMPD3 is involved in anthrax LeTx-induced macrophage cell death. Protein & cell\| PubMed ID: 21822801	2011
Dual colored mesoporous silica nanoparticles with pH activable rhodamine-lactam for ratiometric sensing of lysosomal acidity. Chemical communications (Cambridge, England)\| PubMed ID: 21931895	2011
Chromo-fluorogenic detection of aldehydes with a rhodamine based sensor featuring an intramolecular deoxylactam. Organic & biomolecular chemistry\| PubMed ID: 21947083	2011
Programmed necrosis: backup to and competitor with apoptosis in the immune system. Nature immunology\| PubMed ID: 22089220	2011
A novel function of p38-regulated/activated kinase in endothelial cell migration and tumor angiogenesis. Molecular and cellular biology\| PubMed ID: 22124154	2012
Determinants of public T cell responses. Cell research\| PubMed ID: 22212481	2012
GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy. Science (New York, N.Y.)\| PubMed ID: 22539723	2012
PRAK suppresses oncogenic ras-induced hematopoietic cancer development by antagonizing the JNK pathway. Molecular cancer research : MCR\| PubMed ID: 22665523	2012
Efficient inhibition of HIV-1 replication by an artificial polycistronic miRNA construct. Virology journal\| PubMed ID: 22709537	2012
Protein phosphorylation-acetylation cascade connects growth factor deprivation to autophagy. Autophagy\| PubMed ID: 22717509	2012
Recombinatorial biases and convergent recombination determine interindividual TCRβ sharing in murine thymocytes. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 22826324	2012
Investigation of receptor interacting protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomics. Molecular & cellular proteomics : MCP\| PubMed ID: 22942356	2012
New components of the necroptotic pathway. Protein & cell\| PubMed ID: 23073834	2012
The orphan receptor TR3 participates in angiotensin II-induced cardiac hypertrophy by controlling mTOR signalling. EMBO molecular medicine\| PubMed ID: 23197407	2013
A role of RIP3-mediated macrophage necrosis in atherosclerosis development. Cell reports\| PubMed ID: 23333278	2013
Gene deletion of Gabarap enhances Nlrp3 inflammasome-dependent inflammatory responses. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23427251	2013
Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling. The Journal of biological chemistry\| PubMed ID: 23612963	2013
A potential suppressive effect of natural antisense IL-1β RNA on lipopolysaccharide-induced IL-1β expression. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23677478	2013
Benzothiazoline based chemodosimeters for fluorogenic detection of hypochlorous acid. Bioorganic & medicinal chemistry letters\| PubMed ID: 23777783	2013
Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis. Cell research\| PubMed ID: 23835476	2013
The FoxO-BNIP3 axis exerts a unique regulation of mTORC1 and cell survival under energy stress. Oncogene\| PubMed ID: 23851496	2014
Activation of p38α in T cells regulates the intestinal host defense against attaching and effacing bacterial infections. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23918973	2013
Rhodamine-propargylic esters for detection of mitochondrial hydrogen sulfide in living cells. Bioorganic & medicinal chemistry letters\| PubMed ID: 23973212	2013
COP1 and GSK3β cooperate to promote c-Jun degradation and inhibit breast cancer cell tumorigenesis. Neoplasia (New York, N.Y.)\| PubMed ID: 24027432	2013
Recognition of gut microbiota by NOD2 is essential for the homeostasis of intestinal intraepithelial lymphocytes. The Journal of experimental medicine\| PubMed ID: 24062413	2013
The TNF family member 4-1BBL sustains inflammation by interacting with TLR signaling components during late-phase activation. Science signaling\| PubMed ID: 24084649	2013
AMP as a low-energy charge signal autonomously initiates assembly of AXIN-AMPK-LKB1 complex for AMPK activation. Cell metabolism\| PubMed ID: 24093678	2013
The p38-interacting protein (p38IP) regulates G2/M progression by promoting α-tubulin acetylation via inhibiting ubiquitination-induced degradation of the acetyltransferase GCN5. The Journal of biological chemistry\| PubMed ID: 24220028	2013
Chemokine receptor CX3CR1 contributes to macrophage survival in tumor metastasis. Molecular cancer\| PubMed ID: 24245985	2013
A near-infrared fluorescence dye for sensitive detection of hydrogen sulfide in serum. Bioorganic & medicinal chemistry letters\| PubMed ID: 24295788	2014
Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway. Nature chemical biology\| PubMed ID: 24316735	2014
Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death. Cell research\| PubMed ID: 24366341	2014
Dimeric structure of p300/CBP associated factor. BMC structural biology\| PubMed ID: 24423233	2014
Quantitative phosphoproteomic analysis of RIP3-dependent protein phosphorylation in the course of TNF-induced necroptosis. Proteomics\| PubMed ID: 24453211	2014
HBV life cycle is restricted in mouse hepatocytes expressing human NTCP. Cellular & molecular immunology\| PubMed ID: 24509445	2014
The Gβγ-Src signaling pathway regulates TNF-induced necroptosis via control of necrosome translocation. Cell research\| PubMed ID: 24513853	2014
pelo is required for high efficiency viral replication. PLoS pathogens\| PubMed ID: 24722736	2014
Regulator of G-protein signaling 19 (RGS19) and its partner Gα-inhibiting activity polypeptide 3 (GNAI3) are required for zVAD-induced autophagy and cell death in L929 cells. PloS one\| PubMed ID: 24751948	2014
p38 MAPK regulates steroidogenesis through transcriptional repression of STAR gene. Journal of molecular endocrinology\| PubMed ID: 24780837	2014
A photothermal cell viability-reporting theranostic nanoprobe for intraoperative optical ablation and tracking of tumors. Chemical communications (Cambridge, England)\| PubMed ID: 24918105	2014
The lysosomal v-ATPase-Ragulator complex is a common activator for AMPK and mTORC1, acting as a switch between catabolism and anabolism. Cell metabolism\| PubMed ID: 25002183	2014
The p38 pathway regulates oxidative stress tolerance by phosphorylation of mitochondrial protein IscU. The Journal of biological chemistry\| PubMed ID: 25204651	2014
Centrifugation aided highly sensitive detection of nitrite with a dye-silica conjugate featuring cleavable linkages. Bioorganic & medicinal chemistry letters\| PubMed ID: 25227716	2014
RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway. Nature immunology\| PubMed ID: 25326752	2014
Cationic nanocarriers induce cell necrosis through impairment of Na(+)/K(+)-ATPase and cause subsequent inflammatory response. Cell research\| PubMed ID: 25613571	2015
RIP1/RIP3 binding to HSV-1 ICP6 initiates necroptosis to restrict virus propagation in mice. Cell host & microbe\| PubMed ID: 25674982	2015
Ppm1b negatively regulates necroptosis through dephosphorylating Rip3. Nature cell biology\| PubMed ID: 25751141	2015
Nuclear Export of Smads by RanBP3L Regulates Bone Morphogenetic Protein Signaling and Mesenchymal Stem Cell Differentiation. Molecular and cellular biology\| PubMed ID: 25755279	2015
A Role for Tubular Necroptosis in Cisplatin-Induced AKI. Journal of the American Society of Nephrology : JASN\| PubMed ID: 25788533	2015
Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation. Nature chemical biology\| PubMed ID: 25822914	2015
Recognition of cytosolic DNA attenuates glucose metabolism and induces AMPK mediated energy stress response. International journal of biological sciences\| PubMed ID: 25892965	2015
Lysosomal pH Decrease in Inflammatory Cells Used To Enable Activatable Imaging of Inflammation with a Sialic Acid Conjugated Profluorophore. Analytical chemistry\| PubMed ID: 26035230	2015
ROCK inhibition enhances microRNA function by promoting deadenylation of targeted mRNAs via increasing PAIP2 expression. Nucleic acids research\| PubMed ID: 26187994	2015
Chaperone-mediated autophagy prevents apoptosis by degrading BBC3/PUMA. Autophagy\| PubMed ID: 26212789	2015
TCR-induced sumoylation of the kinase PKC-θ controls T cell synapse organization and T cell activation. Nature immunology\| PubMed ID: 26390157	2015
Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity. Nature immunology\| PubMed ID: 26414765	2015
Group-DIA: analyzing multiple data-independent acquisition mass spectrometry data files. Nature methods\| PubMed ID: 26436481	2015
Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion. Cell research\| PubMed ID: 26611636	2015
MicroRNA-17~92 inhibits colorectal cancer progression by targeting angiogenesis. Cancer letters\| PubMed ID: 27080303	2016
Electrophysiologist shows a cation channel function of MLKL. Cell research\| PubMed ID: 27229313	2016
The Necrosome in Acute Kidney Injury. Seminars in nephrology\| PubMed ID: 27339385	2016
Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis. Cell research\| PubMed ID: 27573174	2016
Repression of MicroRNA Function Mediates Inflammation-associated Colon Tumorigenesis. Gastroenterology\| PubMed ID: 27825961	2017
p38α has an important role in antigen cross-presentation by dendritic cells. Cellular & molecular immunology\| PubMed ID: 27867197	2018
The MLKL Channel in Necroptosis Is an Octamer Formed by Tetramers in a Dyadic Process. Molecular and cellular biology\| PubMed ID: 27920255	2017
RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome. Nature communications\| PubMed ID: 28176780	2017
Differential Sensitivity of Target Genes to Translational Repression by miR-17~92. PLoS genetics\| PubMed ID: 28241004	2017
Responsive hetero-organelle partition conferred fluorogenic sensing of mitochondrial depolarization. Chemical science\| PubMed ID: 28451305	2017
The transcriptional coactivator TAZ regulates reciprocal differentiation of T17 cells and T cells. Nature immunology\| PubMed ID: 28504697	2017
2-HG Inhibits Necroptosis by Stimulating DNMT1-Dependent Hypermethylation of the RIP3 Promoter. Cell reports\| PubMed ID: 28564603	2017
The RIP3-RIP1-NF-κB signaling axis is dispensable for necroptotic cells to elicit cross-priming of CD8 T cells. Cellular & molecular immunology\| PubMed ID: 28626232	2017
Defining Cancer Cell Bioenergetic Profiles Using a Dual Organelle-Oriented Chemosensor Responsive to pH Values and Electropotential Changes. Analytical chemistry\| PubMed ID: 28627881	2017
A sialic acid-targeted near-infrared theranostic for signal activation based intraoperative tumor ablation. Chemical science\| PubMed ID: 28706639	2015
A carbohydrate-grafted nanovesicle with activatable optical and acoustic contrasts for dual modality high performance tumor imaging. Chemical science\| PubMed ID: 28706650	2015
Protein kinase D at the Golgi controls NLRP3 inflammasome activation. The Journal of experimental medicine\| PubMed ID: 28716882	2017
Imaging Lysosomal pH Alteration in Stressed Cells with a Sensitive Ratiometric Fluorescence Sensor. ACS sensors\| PubMed ID: 28723201	2017
Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation. Nature cell biology\| PubMed ID: 28752853	2017
Correction for Chen et al., "Nuclear Export of Smads by RanBP3L Regulates Bone Morphogenetic Protein Signaling and Mesenchymal Stem Cell Differentiation". Molecular and cellular biology\| PubMed ID: 28801455	2017
Plasma membrane changes during programmed cell deaths. Cell research\| PubMed ID: 29076500	2018
RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis. Nature cell biology\| PubMed ID: 29358703	2018
Publisher Correction: The transcriptional coactivator TAZ regulates reciprocal differentiation of T17 cells and T cells. Nature immunology\| PubMed ID: 29449628	2018
RIP3 is an upregulator of aerobic metabolism and the enhanced respiration by necrosomal RIP3 feeds back on necrosome to promote necroptosis. Cell death and differentiation\| PubMed ID: 29523873	2018
Bioorthogonal Conjugation Directed by a Sugar-Sorting Pathway for Continual Tracking of Stressed Organelles. Angewandte Chemie (International ed. in English)\| PubMed ID: 29889361	2018
miR-30 disrupts senescence and promotes cancer by targeting both p16 and DNA damage pathways. Oncogene\| PubMed ID: 29907771	2018
Redirecting immunity covalently incorporated immunogenic sialic acid on the tumor cell surface. Chemical science\| PubMed ID: 29997860	2016
Author Correction: Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation. Nature cell biology\| PubMed ID: 30018319	2018
Bifunctional Super-resolution Imaging Probe with Acidity-Independent Lysosome-Retention Mechanism. Analytical chemistry\| PubMed ID: 30148356	2018
Senescence-associated sialidase revealed by an activatable fluorescence-on labeling probe. Chemical communications (Cambridge, England)\| PubMed ID: 30259042	2018
Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis. Cell research\| PubMed ID: 30287942	2018
On the use of abiotic sialic acids to attenuate cell inflammation. Scientific reports\| PubMed ID: 30470771	2018
Inactivation of Cyclic AMP Response Element Transcription Caused by Constitutive p38 Activation Is Mediated by Hyperphosphorylation-Dependent CRTC2 Nucleocytoplasmic Transport. Molecular and cellular biology\| PubMed ID: 30782776	2019
Quantification of Dynamic Protein Interactions and Phosphorylation in LPS Signaling Pathway by SWATH-MS. Molecular & cellular proteomics : MCP\| PubMed ID: 30850422	2019
Macrophage p38α promotes nutritional steatohepatitis through M1 polarization. Journal of hepatology\| PubMed ID: 30914267	2019
High mobility group box 1 enables bacterial lipids to trigger receptor-interacting protein kinase 3 (RIPK3)-mediated necroptosis and apoptosis in mice. The Journal of biological chemistry\| PubMed ID: 31000631	2019
ZBP1 mediates interferon-induced necroptosis. Cellular & molecular immunology\| PubMed ID: 31076724	2020
An in cellulo-activated multicolor cell labeling approach used to image dying cell clearance. The Analyst\| PubMed ID: 31268078	2019
Efficient engulfment of necroptotic and pyroptotic cells by nonprofessional and professional phagocytes. Cell discovery\| PubMed ID: 31632688	2019
Systematic Assessment of the Effect of Internal Library in Targeted Analysis of SWATH-MS. Journal of proteome research\| PubMed ID: 31664839	2020
Organelle-Redirected Chameleon Sensor-Enabled Live Cell Imaging of Mitochondrial DNA. Analytical chemistry\| PubMed ID: 31743646	2019
Bacterial Endotoxin Activates the Coagulation Cascade through Gasdermin D-Dependent Phosphatidylserine Exposure. Immunity\| PubMed ID: 31836429	2019
Manipulation of Host Cell Death Pathways by Herpes Simplex Virus. Current topics in microbiology and immunology\| PubMed ID: 32060646	2023
Generation of a murine SWATH-MS spectral library to quantify more than 11,000 proteins. Scientific data\| PubMed ID: 32218446	2020
Gut stem cell necroptosis by genome instability triggers bowel inflammation. Nature\| PubMed ID: 32296174	2020
SAMD4 family members suppress human hepatitis B virus by directly binding to the Smaug recognition region of viral RNA. Cellular & molecular immunology\| PubMed ID: 32341522	2021
The p38-interacting protein p38IP suppresses TCR and LPS signaling by targeting TAK1. EMBO reports\| PubMed ID: 32410369	2020
Targeting RIPK3 oligomerization blocks necroptosis without inducing apoptosis. FEBS letters\| PubMed ID: 32412649	2020
Traceless protein delivery with an efficient recyclable nanocarrier. Biomaterials science\| PubMed ID: 32481960	2013
A targetable acid-responsive micellar system for signal activation based high performance surgical resolution of tumors. Biomaterials science\| PubMed ID: 32481970	2014
A fluorescently labelled sialic acid for high performance intraoperative tumor detection. Biomaterials science\| PubMed ID: 32482007	2014
An overview of mammalian p38 mitogen-activated protein kinases, central regulators of cell stress and receptor signaling. F1000Research\| PubMed ID: 32612808	2020
Erratum to: "Macrophage p38 alpha promotes nutritional steatohepatitis through M1 polarization (J Hepatol 2019; 71(1):163-174)". Journal of hepatology\| PubMed ID: 32690378	2020
A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade. Molecular cell\| PubMed ID: 32979304	2020
RNA N-Methyladenosine Methyltransferase METTL3 Facilitates Colorectal Cancer by Activating the mA-GLUT1-mTORC1 Axis and Is a Therapeutic Target. Gastroenterology\| PubMed ID: 33217448	2021
Endogenous Retroelement Activation by Epigenetic Therapy Reverses the Warburg Effect and Elicits Mitochondrial-Mediated Cancer Cell Death. Cancer discovery\| PubMed ID: 33355179	2021
RIP1-dependent linear and nonlinear recruitments of caspase-8 and RIP3 respectively to necrosome specify distinct cell death outcomes. Protein & cell\| PubMed ID: 33389663	2021
An organelle-directed chemical ligation approach enables dual-color detection of mitophagy. Autophagy\| PubMed ID: 33435798	2021
Detection of necroptosis by phospho-MLKL immunohistochemical labeling. STAR protocols\| PubMed ID: 33458710	2021
The essential role of PRAK in tumor metastasis and its therapeutic potential. Nature communications\| PubMed ID: 33741957	2021
Installation of high-affinity Siglec-1 ligand on tumor surface for macrophage-engaged tumor suppression. Bioorganic & medicinal chemistry letters\| PubMed ID: 34425200	2021
Pyroptosis of syncytia formed by fusion of SARS-CoV-2 spike and ACE2-expressing cells. Cell discovery\| PubMed ID: 34429403	2021
A unique death pathway keeps RIPK1 D325A mutant mice in check at embryonic day 10.5. PLoS biology\| PubMed ID: 34437534	2021
Dice-XMBD: Deep Learning-Based Cell Segmentation for Imaging Mass Cytometry. Frontiers in genetics\| PubMed ID: 34603385	2021
Glycogen synthase kinase 3 drives thymocyte egress by suppressing β-catenin activation of Akt. Science advances\| PubMed ID: 34623920	2021
Deep representation features from DreamDIA improve the analysis of data-independent acquisition proteomics. Communications biology\| PubMed ID: 34650228	2021
NLRC4 inflammasome-dependent cell death occurs by a complementary series of three death pathways and determines lethality in mice. Science advances\| PubMed ID: 34678072	2021
synthesis of dendrimeric sensors for fluorescence-on imaging of bacterial phagocytosis. Journal of materials chemistry. B\| PubMed ID: 34761795	2022
Gasdermin E mediates photoreceptor damage by all-trans-retinal in the mouse retina. The Journal of biological chemistry\| PubMed ID: 34973334	2022
MSSort-DIA: A deep learning classification tool of the peptide precursors quantified by OpenSWATH. Journal of proteomics\| PubMed ID: 35231660	2022
Mosaic composition of RIP1-RIP3 signalling hub and its role in regulating cell death. Nature cell biology\| PubMed ID: 35256774	2022
Dual ligand engagement for noncanonical inflammasome activation. Nature immunology\| PubMed ID: 35487984	2022
DAISM-DNN: Highly accurate cell type proportion estimation with data augmentation and deep neural networks. Patterns (New York, N.Y.)\| PubMed ID: 35510186	2022
Biocapture-Directed Chemical Labeling for Discerning Stressed States of Organelles. Analytical chemistry\| PubMed ID: 35754322	2022
Immunostaining of phospho-RIPK3 in L929 cells, murine yolk sacs, ceca, and small intestines. STAR protocols\| PubMed ID: 35779260	2022
Protocol to estimate cell type proportions from bulk RNA-seq using DAISM-DNN. STAR protocols\| PubMed ID: 35942344	2022
Rethinking sepsis after a two-year battle with COVID-19. Cellular & molecular immunology\| PubMed ID: 36050479	2022
A p38α-BLIMP1 signalling pathway is essential for plasma cell differentiation. Nature communications\| PubMed ID: 36443297	2022
Sensitive imaging of Endoplasmic reticulum (ER) autophagy with an acidity-reporting ER-Tracker. Autophagy\| PubMed ID: 36625032	2023
Ribosome-rescuer PELO catalyzes the oligomeric assembly of NOD-like receptor family proteins via activating their ATPase enzymatic activity. Immunity\| PubMed ID: 36948192	2023
Dear-DIA: Deep Autoencoder Enables Deconvolution of Data-Independent Acquisition Proteomics. Research (Washington, D.C.)\| PubMed ID: 37377457	2023
Fluorescence-On Imaging of Reticulophagy Enabled by an Acidity-Reporting Solvatochromic Probe. Analytical chemistry\| PubMed ID: 37463355	2023
Protocol for reconstitution of oligomeric assembly of NAIP5-NLRC4 inflammasome in vitro. STAR protocols\| PubMed ID: 37733592	2023
Anthrax lethal toxin and tumor necrosis factor-α synergize on intestinal epithelia to induce mouse death. Protein & cell\| PubMed ID: 37855658	2024
Optimal tagging strategies for illuminating expression profiles of genes with different abundance in zebrafish. Communications biology\| PubMed ID: 38129658	2023
COVID-19 vaccines and beyond. Cellular & molecular immunology\| PubMed ID: 38273150	2024
Bypassing PELO-mediated ATPase activation of the NLR is a common pathogenic cause of NLR-associated autoinflammatory diseases. Cellular & molecular immunology\| PubMed ID: 38632384	2024
Phosphorylation of caspase-8 by RSKs via organ-constrained effects controls the sensitivity to TNF-induced death. Cell death discovery\| PubMed ID: 38789425	2024
Signal-Sustained Imaging of Mitophagy with an Enzyme-Activatable Metabolic Lipid Labeling Probe. Autophagy\| PubMed ID: 38873937	2024
Author Correction: RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis. Nature cell biology\| PubMed ID: 38877086	2024
AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine. Cell research\| PubMed ID: 38898113	2024
ZBTB21 suppresses CRE-mediated transcription to impair synaptic function in Down syndrome. Science advances\| PubMed ID: 38959316	2024
Lymphatic-localized Treg-mregDC crosstalk limits antigen trafficking and restrains anti-tumor immunity. Cancer cell\| PubMed ID: 39029466	2024
Cecal necroptosis triggers lethal cardiac dysfunction in TNF-induced severe SIRS. Cell reports\| PubMed ID: 39325617	2024
Dear-PSM: A deep learning-based peptide search engine enables full database search for proteomics. Smart medicine\| PubMed ID: 39420951	2024
Residue Y362 is crucial for FLIP to impart catalytic activity to pro-caspase-8 to suppress necroptosis. Cell reports\| PubMed ID: 39520684	2024
A GSDMD agonist boosts specific antitumor immunity. Cell research\| PubMed ID: 39538026	2024
p38α-eIF6-Nsun2 axis promotes ILC3's rapid response to protect host from intestinal inflammation. The Journal of experimental medicine\| PubMed ID: 39589554	2025