non-invasive-visualization-nailbed-microvascular-morphology-mice

Non-Invasive Visualization of Nailbed Microvascular Morphology in Mice Using Capillaroscopy

Imaging microcapillary networks of the skin in humans using nailfold capillaroscopy (NFC) has underscored the importance of microcirculation as a target ...

Harvard Medical School

To analyze optic disc hemorrhages (DH) associated with primary open-angle glaucoma by quantifying their geometric profile and comparing their densitometry with hemorrhages from retinal vein occlusions (RVO) and retinal macroaneurysms (MA), which have venous and arterial sources of bleeding, respectively.

Fundus Densitometry Findings Suggest Optic Disc Hemorrhages in Primary Open-Angle Glaucoma Have an Arterial Origin.

An altered haemodynamic profile for various ocular posterior segment capillary beds has been documented in primary open-angle glaucoma (POAG). POAG may also involve abnormal non-ocular blood flow, and the nailfold capillaries, which are not affected by elevated intraocular pressure (IOP), are readily assessable.

Resting nailfold capillary blood flow in primary open-angle glaucoma.

Cerebrovascular disease (CVD) is highly comorbid with Alzheimer's disease (AD), yet its role is not entirely understood. Nailfold video capillaroscopy (NVC) is a noninvasive method of live imaging the capillaries near the fingernail's cuticle and may help to describe further vascular contributions to AD.

Nailfold Capillary Morphology in Alzheimer's Disease Dementia.

A genetic correlation is the proportion of phenotypic variance between traits that is shared on a genetic basis. Here we explore genetic correlations between diabetes- and glaucoma-related traits.

Genetic Correlations Between Diabetes and Glaucoma: An Analysis of Continuous and Dichotomous Phenotypes.

To assess microvascular beds in the optic nerve head (ONH), peripapillary tissue, and the nailfold in patients with primary open-angle glaucoma (POAG) versus controls.

Paired Optic Nerve Microvasculature and Nailfold Capillary Measurements in Primary Open-Angle Glaucoma.

The purpose of this study was to describe the genetic relationship between smoking and glaucoma.

Article	Year
Fundus Densitometry Findings Suggest Optic Disc Hemorrhages in Primary Open-Angle Glaucoma Have an Arterial Origin. American journal of ophthalmology\| PubMed ID: 29330062	2018
Resting nailfold capillary blood flow in primary open-angle glaucoma. The British journal of ophthalmology\| PubMed ID: 29699986	2019
Nailfold Capillary Morphology in Alzheimer's Disease Dementia. Journal of Alzheimer's disease : JAD\| PubMed ID: 30320588	2018
Genetic Correlations Between Diabetes and Glaucoma: An Analysis of Continuous and Dichotomous Phenotypes. American journal of ophthalmology\| PubMed ID: 31121135	2019
Paired Optic Nerve Microvasculature and Nailfold Capillary Measurements in Primary Open-Angle Glaucoma. Translational vision science & technology\| PubMed ID: 34110389	2021
Genetic Associations Between Smoking- and Glaucoma-Related Traits. Translational vision science & technology\| PubMed ID: 36786746	2023

Clara C. Cousins

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