Ana Marisa Chudzinski-Tavassi

Center of Excellence in New Target Discovery, Butantan Institute

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2025

Other Publications

Article	Year
A prothrombin activator (Lopap) modulating inflammation, coagulation and cell survival mechanisms. Biochemical and biophysical research communications\| PubMed ID: 15963468	2005
Protein mapping of the salivary complex from a hematophagous leech. Omics : a journal of integrative biology\| PubMed ID: 15969650	2005
Releasing or expression modulating mediator involved in hemostasis by Berythractivase and Jararhagin (SVMPs). Toxicon : official journal of the International Society on Toxinology\| PubMed ID: 16626772	2006
Exploring new molecules and activities from Lonomia obliqua caterpillars. Pathophysiology of haemostasis and thrombosis\| PubMed ID: 16707933	2005
The venom of the Lonomia caterpillar: an overview. Toxicon : official journal of the International Society on Toxinology\| PubMed ID: 17320134	2007
A lipocalin sequence signature modulates cell survival. FEBS letters\| PubMed ID: 20471382	2010
Pro-apoptotic effects of Amblyomin-X in murine renal cell carcinoma "in vitro". Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 22281290	2012
A lipocalin-derived Peptide modulating fibroblasts and extracellular matrix proteins. Journal of toxicology\| PubMed ID: 22737165	2012
Functional characterisation of vizottin, the first factor Xa inhibitor purified from the leech Haementeria vizottoi. Thrombosis and haemostasis\| PubMed ID: 22782262	2012
A Kunitz-type FXa inhibitor affects tumor progression, hypercoagulable state and triggers apoptosis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 23433900	2013
Rational development of novel leads from animal secretion based on coagulation and cell targets: 1. In silico analysis to explore a peptide derivative as lipocalins' signature. Toxicon : official journal of the International Society on Toxinology\| PubMed ID: 23435263	2013
Transcripts involved in hemostasis: Exploring salivary complexes from Haementeria vizottoi leeches through transcriptomics, phylogenetic studies and structural features. Toxicon : official journal of the International Society on Toxinology\| PubMed ID: 26363292	2015
Specific role of cytoplasmic dynein in the mechanism of action of an antitumor molecule, Amblyomin-X. Experimental cell research\| PubMed ID: 26748183	2016
Tick salivary gland as potential natural source for the discovery of promising antitumor drug candidates. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 26796259	2016
Harnessing the knowledge of animal toxins to generate drugs. Pharmacological research\| PubMed ID: 26826284	2016
Amblyomin-X induces ER stress, mitochondrial dysfunction, and caspase activation in human melanoma and pancreatic tumor cell. Molecular and cellular biochemistry\| PubMed ID: 27015684	2016
Mesenchymal stem cell-like properties of CD133+ glioblastoma initiating cells. Oncotarget\| PubMed ID: 27244897	2016
Hemolin triggers cell survival on fibroblasts in response to serum deprivation by inhibition of apoptosis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 27470394	2016
Amblyomin-X having a Kunitz-type homologous domain, is a noncompetitive inhibitor of FXa and induces anticoagulation in vitro and in vivo. Biochimica et biophysica acta\| PubMed ID: 27479486	2016
Promising pharmacological profile of a Kunitz-type inhibitor in murine renal cell carcinoma model. Oncotarget\| PubMed ID: 27566592	2016
Exploring the in vivo wound healing effects of a recombinant hemolin from the caterpillar . The journal of venomous animals and toxins including tropical diseases\| PubMed ID: 28031734	2016
Revisiting antithrombotic therapeutics; sculptin, a novel specific, competitive, reversible, scissile and tight binding inhibitor of thrombin. Scientific reports\| PubMed ID: 28469161	2017
Establishment of primary cell culture and an intracranial xenograft model of pediatric ependymoma: a prospect for therapy development and understanding of tumor biology. Oncotarget\| PubMed ID: 29774098	2018
A Combined Computer-Aided Approach to Drive the Identification of Potential Epitopes in Protein Therapeutics. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques\| PubMed ID: 30011260	2018
Biodistribution and Pharmacokinetics of Amblyomin-X, a Novel Antitumour Protein Drug in Healthy Mice. European journal of drug metabolism and pharmacokinetics\| PubMed ID: 30132264	2019
Amblyomin-X, a recombinant Kunitz-type inhibitor, regulates cell adhesion and migration of human tumor cells. Cell adhesion & migration\| PubMed ID: 30238848	2020
Tropism of mesenchymal stem cell toward CD133 stem cell of glioblastoma in vitro and promote tumor proliferation in vivo. Stem cell research & therapy\| PubMed ID: 30413179	2018
Corrigendum to "Pro-apoptotic effects of Amblyomin-X in murine renal cell carcinoma "in vitro" [Biomed. Pharmacother. 66 (2012) 64-69]. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 31235339	2019
New therapeutic target for pediatric anaplastic ependymoma control: study of anti-tumor activity by a Kunitz-type molecule, Amblyomin-X. Scientific reports\| PubMed ID: 31292491	2019
Inflammation Induced by Platelet-Activating Viperid Snake Venoms: Perspectives on Thromboinflammation. Frontiers in immunology\| PubMed ID: 31572356	2019
Emerging Roles and Potential Applications of Non-Coding RNAs in Glioblastoma. International journal of molecular sciences\| PubMed ID: 32283739	2020
Modulation of stress and immune response by Amblyomin-X results in tumor cell death in a horse melanoma model. Scientific reports\| PubMed ID: 32286411	2020
Human Chondrocyte Activation by Toxins From , an Amazon Rainforest Moth Caterpillar: Identifying an Osteoarthritis Signature. Frontiers in immunology\| PubMed ID: 33072083	2020
Venom Induces NF-κB Activation and a Pro-Inflammatory Profile in THP-1-Derived Macrophage. Toxins\| PubMed ID: 34209394	2021
Envenoming and Innovative Research. Toxins\| PubMed ID: 34941670	2021
Novel Cysteine Protease Inhibitor Derived from the Leech: Recombinant Expression, Purification, and Characterization. Toxins\| PubMed ID: 34941695	2021
rDromaserpin: A Novel Anti-Hemostatic Serpin, from the Salivary Glands of the Hard Tick . Toxins\| PubMed ID: 34941750	2021
Human Sensory Neuron-like Cells and Glycated Collagen Matrix as a Model for the Screening of Analgesic Compounds. Cells\| PubMed ID: 35053363	2022
Detection of SARS-CoV-2 virus via dynamic light scattering using antibody-gold nanoparticle bioconjugates against viral spike protein. Talanta\| PubMed ID: 35272155	2022
Anti-SARS-CoV-2 equine F (Ab') immunoglobulin as a possible therapy for COVID-19. Scientific reports\| PubMed ID: 35273234	2022
The phytoactive constituents of B.D. Jacks (pitangatuba): Toxicity and elucidation of their anti-inflammatory mechanism(s) of action. Food chemistry. Molecular sciences\| PubMed ID: 35415693	2022
Losac and Lopap Recombinant Proteins from Bristles Positively Modulate the Myoblast Proliferation Process. Frontiers in molecular biosciences\| PubMed ID: 35847970	2022
Equine Anti-SARS-CoV-2 Serum (ECIG) Binds to Mutated RBDs and N Proteins of Variants of Concern and Inhibits the Binding of RBDs to ACE-2 Receptor. Frontiers in immunology\| PubMed ID: 35898497	2022
Proteomic Analysis Identifies Molecular Players and Biological Processes Specific to SARS-CoV-2 Exposure in Endothelial Cells. International journal of molecular sciences\| PubMed ID: 36142365	2022
Comparative Effects of Intra-Articular versus Intravenous Mesenchymal Stromal Cells Therapy in a Rat Model of Osteoarthritis by Destabilization of Medial Meniscus. International journal of molecular sciences\| PubMed ID: 37958526	2023
Identification of purinergic system components in the venom of Bothrops mattogrossensis and the inhibitory effect of specioside extracted from Tabebuia aurea. Purinergic signalling\| PubMed ID: 38958820	2024
Correction: Bufalo et al. Human Sensory Neuron-like Cells and Glycated Collagen Matrix as a Model for the Screening of Analgesic Compounds. 2022, , 247. Cells\| PubMed ID: 38995017	2024
Crotoxin induces cytotoxic effects in human malignant melanoma cells in both native and detoxified forms. Frontiers in pharmacology\| PubMed ID: 39114354	2024
Comparison between biliary plastic stents with and without application of silver nanoparticles: an in-vitro study of the biofilm formation. Acta cirurgica brasileira\| PubMed ID: 40172368	2025
Translational insights into statin-induced myotoxicity: Differential impact of lipophilic and hydrophilic statins on iPSC-derived skeletal muscle cells from patients with familial hyperchole... Toxicology\| PubMed ID: 40254247	2025