David A. Haake

Department of Urology, University of California, Los Angeles

Affiliated withUniversity of California, Los Angeles Veterans Affairs Greater Los Angeles Healthcare System David Geffen School of Medicine at University of California Los Angeles

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 6	2013
Publication title Cited by 3	2017

Other Publications

Article	Year
Novel 45-kilodalton leptospiral protein that is processed to a 31-kilodalton growth-phase-regulated peripheral membrane protein. Infection and immunity\| PubMed ID: 11748198	2002
Leptospirosis, water sports, and chemoprophylaxis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 11941571	2002
Global analysis of outer membrane proteins from Leptospira interrogans serovar Lai. Infection and immunity\| PubMed ID: 11953365	2002
Gastrointestinal microflora studies in late-onset autism. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 12173102	2002
Characterization of the leptospiral outer membrane and description of three novel leptospiral membrane proteins. Infection and immunity\| PubMed ID: 12183539	2002
An improved immunohistochemical diagnostic technique for canine leptospirosis using antileptospiral antibodies on renal tissue. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc\| PubMed ID: 12680639	2002
LipL21 is a novel surface-exposed lipoprotein of pathogenic Leptospira species. Infection and immunity\| PubMed ID: 12704111	2003
Pathogenic Leptospira species express surface-exposed proteins belonging to the bacterial immunoglobulin superfamily. Molecular microbiology\| PubMed ID: 12890019	2003
Molecular evolution and mosaicism of leptospiral outer membrane proteins involves horizontal DNA transfer. Journal of bacteriology\| PubMed ID: 15090524	2004
Outer membrane proteins of pathogenic spirochetes. FEMS microbiology reviews\| PubMed ID: 15449605	2004
Osmolarity, a key environmental signal controlling expression of leptospiral proteins LigA and LigB and the extracellular release of LigA. Infection and immunity\| PubMed ID: 15618142	2005
Rapid, species-specific detection of uropathogen 16S rDNA and rRNA at ambient temperature by dot-blot hybridization and an electrochemical sensor array. Molecular genetics and metabolism\| PubMed ID: 15639199	2005
Diagnostic and therapeutic pitfalls associated with primaquine-tolerant Plasmodium vivax. Journal of clinical microbiology\| PubMed ID: 15695723	2005
Leptospiral membrane proteins--variations on a theme? The Indian journal of medical research\| PubMed ID: 15802754	2005
Surfaceome of Leptospira spp. Infection and immunity\| PubMed ID: 16040999	2005
Electrochemical molecular analysis without nucleic acid amplification. Methods (San Diego, Calif.)\| PubMed ID: 16213156	2005
Leptospirosis after recreational exposure to water in the Yaeyama islands, Japan. The American journal of tropical medicine and hygiene\| PubMed ID: 16222003	2005
LruA and LruB, novel lipoproteins of pathogenic Leptospira interrogans associated with equine recurrent uveitis. Infection and immunity\| PubMed ID: 16239521	2005
Lipoprotein computational prediction in spirochaetal genomes. Microbiology (Reading, England)\| PubMed ID: 16385121	2006
Use of electrochemical DNA biosensors for rapid molecular identification of uropathogens in clinical urine specimens. Journal of clinical microbiology\| PubMed ID: 16455913	2006
Molecular epidemiology of leptospirosis in the Amazon. PLoS medicine\| PubMed ID: 16933961	2006
Effects of temperature on gene expression patterns in Leptospira interrogans serovar Lai as assessed by whole-genome microarrays. Infection and immunity\| PubMed ID: 16988264	2006
LipL46 is a novel surface-exposed lipoprotein expressed during leptospiral dissemination in the mammalian host. Microbiology (Reading, England)\| PubMed ID: 17159228	2006
Physiological osmotic induction of Leptospira interrogans adhesion: LigA and LigB bind extracellular matrix proteins and fibrinogen. Infection and immunity\| PubMed ID: 17296754	2007
Leptospira immunoglobulin-like proteins as a serodiagnostic marker for acute leptospirosis. Journal of clinical microbiology\| PubMed ID: 17360842	2007
Response of Leptospira interrogans to physiologic osmolarity: relevance in signaling the environment-to-host transition. Infection and immunity\| PubMed ID: 17371863	2007
Development of an advanced electrochemical DNA biosensor for bacterial pathogen detection. The Journal of molecular diagnostics : JMD\| PubMed ID: 17384207	2007
The terminal portion of leptospiral immunoglobulin-like protein LigA confers protective immunity against lethal infection in the hamster model of leptospirosis. Vaccine\| PubMed ID: 17629368	2007
Leptospira interrogans endostatin-like outer membrane proteins bind host fibronectin, laminin and regulators of complement. PloS one\| PubMed ID: 18000555	2007
Early diagnosis of leptospirosis by immunoglobulin M immunoblot testing. Clinical and vaccine immunology : CVI\| PubMed ID: 18184827	2008
Rapid antimicrobial susceptibility determination of uropathogens in clinical urine specimens by use of ATP bioluminescence. Journal of clinical microbiology\| PubMed ID: 18272708	2008
Optimal probe length and target location for electrochemical detection of selected uropathogens at ambient temperature. Journal of clinical microbiology\| PubMed ID: 18562584	2008
Hamster model of leptospirosis. Current protocols in microbiology\| PubMed ID: 18770576	2006
Uropathogens and host characteristics. Journal of clinical microbiology\| PubMed ID: 18842936	2008
Genetic diversity of the Leptospiral immunoglobulin-like (Lig) genes in pathogenic Leptospira spp. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases\| PubMed ID: 19028604	2009
An unsteady microfluidic T-form mixer perturbed by hydrodynamic pressure. Journal of micromechanics and microengineering : structures, devices, and systems\| PubMed ID: 19177174	2008
Leptospira interrogans stably infects zebrafish embryos, altering phagocyte behavior and homing to specific tissues. PLoS neglected tropical diseases\| PubMed ID: 19547748	2009
A comprehensive approach to identification of surface-exposed, outer membrane-spanning proteins of Leptospira interrogans. PloS one\| PubMed ID: 19562037	2009
Multiplex pathogen identification for polymicrobial urinary tract infections using biosensor technology: a prospective clinical study. The Journal of urology\| PubMed ID: 19837423	2009
Potentiometric detection of DNA hybridization using enzyme-induced metallization and a silver ion selective electrode. Analytical chemistry\| PubMed ID: 19908886	2009
Leptospira: a spirochaete with a hybrid outer membrane. Molecular microbiology\| PubMed ID: 20598085	2010
Transcriptional response of Leptospira interrogans to iron limitation and characterization of a PerR homolog. Infection and immunity\| PubMed ID: 20805337	2010
The OmpL37 surface-exposed protein is expressed by pathogenic Leptospira during infection and binds skin and vascular elastin. PLoS neglected tropical diseases\| PubMed ID: 20844573	2010
Ternary Surface Monolayers for Ultrasensitive (Zeptomole) Amperometric Detection of Nucleic Acid Hybridization without Signal Amplification. Analytical chemistry\| PubMed ID: 20883023	2010
Bacterial biofilm disruption using laser generated shockwaves. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference\| PubMed ID: 21096997	2010
Laser induced shockwaves on flexible polymers for treatment of bacterial biofilms. Studies in health technology and informatics\| PubMed ID: 21335826	2011
Redox cycling amplified electrochemical detection of DNA hybridization: application to pathogen E. coli bacterial RNA. Analytica chimica acta\| PubMed ID: 21338752	2011
The multifunctional LigB adhesin binds homeostatic proteins with potential roles in cutaneous infection by pathogenic Leptospira interrogans. PloS one\| PubMed ID: 21347378	2011
Ternary monolayers as DNA recognition interfaces for direct and sensitive electrochemical detection in untreated clinical samples. Biosensors & bioelectronics\| PubMed ID: 21377347	2011
Interactions of leptospira with environmental bacteria from surface water. Current microbiology\| PubMed ID: 21479795	2011
Heterologous expression of pathogen-specific genes ligA and ligB in the saprophyte Leptospira biflexa confers enhanced adhesion to cultured cells and fibronectin. BMC microbiology\| PubMed ID: 21658265	2011
Highly sensitive disposable nucleic acid biosensors for direct bioelectronic detection in raw biological samples. Talanta\| PubMed ID: 21807191	2011
Target-specific capture enhances sensitivity of electrochemical detection of bacterial pathogens. Journal of clinical microbiology\| PubMed ID: 21940468	2011
Methylation and in vivo expression of the surface-exposed Leptospira interrogans outer membrane protein OmpL32. Microbiology (Reading, England)\| PubMed ID: 22174381	2011
A LigA three-domain region protects hamsters from lethal infection by Leptospira interrogans. PLoS neglected tropical diseases\| PubMed ID: 22180800	2011
Three-Dimensional Structures of Pathogenic and Saprophytic Leptospira Revealed by Cryo-Electron Tomography. Journal of bacteriology\| PubMed ID: 22228733	2012
Antibodies to a novel leptospiral protein, LruC, in the eye fluids and sera of horses with Leptospira-associated uveitis. Clinical and vaccine immunology : CVI\| PubMed ID: 22237897	2012
Multiple leptospiral sphingomyelinases (or are there?). Microbiology (Reading, England)\| PubMed ID: 22422753	2012
FlaA proteins in Leptospira interrogans are essential for motility and virulence but are not required for formation of the flagellum sheath. Infection and immunity\| PubMed ID: 22451522	2012
Leptospiral outer membrane protein microarray, a novel approach to identification of host ligand-binding proteins. Journal of bacteriology\| PubMed ID: 22961849	2012
Rapid antimicrobial susceptibility testing by sensitive detection of precursor rRNA using a novel electrochemical biosensing platform. Antimicrobial agents and chemotherapy\| PubMed ID: 23229486	2013
LipL32 Is a Subsurface Lipoprotein of Leptospira interrogans: presentation of new data and reevaluation of previous studies. PloS one\| PubMed ID: 23323152	2013