Stephen M. Hewitt

Histopathology and Autopsy Pathology, National Institutes of Health

Affiliated withNational Institutes of Health

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 2	2025

Other Publications

Article	Year
The paraffin-embedded RNA metric (PERM) for RNA isolated from formalin-fixed, paraffin-embedded tissue. BioTechniques\| PubMed ID: 27177816	2016
Evaluation of non-formalin tissue fixation for molecular profiling studies. The American journal of pathology\| PubMed ID: 11839565	2002
Specimen morcellation after laparoscopic radical nephrectomy: confirmation of histologic diagnosis using needle biopsy. Journal of endourology\| PubMed ID: 11962561	2002
Frozen protein arrays: a new method for arraying and detecting recombinant and native tissue proteins. Proteomics\| PubMed ID: 12442248	2002
NAD(P)H oxidase 1, a product of differentiated colon epithelial cells, can partially replace glycoprotein 91phox in the regulated production of superoxide by phagocytes. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12817011	2003
Ethyl pyruvate decreases sepsis-induced acute renal failure and multiple organ damage in aged mice. Kidney international\| PubMed ID: 14531793	2003
Comparative evaluation of super high-resolution CT scan and virtual bronchoscopy for the detection of tracheobronchial malignancies. Chest\| PubMed ID: 14605057	2003
Peak stimulated insulin secretion is associated with specific changes in gene expression profiles in sporadic insulinomas. Surgery\| PubMed ID: 14668731	2003
The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis. Nature medicine\| PubMed ID: 14704791	2004
Design, construction, and use of tissue microarrays. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 15020780	2004
Loss of antigenicity in stored sections of breast cancer tissue microarrays. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology\| PubMed ID: 15066936	2004
Vitamin C pharmacokinetics: implications for oral and intravenous use. Annals of internal medicine\| PubMed ID: 15068981	2004
Discovery of protein biomarkers for renal diseases. Journal of the American Society of Nephrology : JASN\| PubMed ID: 15213255	2004
Evaluation of biologic end points and pharmacokinetics in patients with metastatic breast cancer after treatment with erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor... Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 15284258	2004
Perspectives in tissue microarrays. Combinatorial chemistry & high throughput screening\| PubMed ID: 15379629	2004
Infrared spectroscopic imaging for histopathologic recognition. Nature biotechnology\| PubMed ID: 15793574	2005
Tissue microarrays: bridging the gap between research and the clinic. Expert review of proteomics\| PubMed ID: 16000080	2005
Transfer and multiplex immunoblotting of a paraffin embedded tissue. Proteomics\| PubMed ID: 16400680	2006
Intravenously administered vitamin C as cancer therapy: three cases. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne\| PubMed ID: 16567755	2006
Tissue microarrays as a platform for proteomic investigation. Journal of molecular histology\| PubMed ID: 16953460	2007
Layered expression scanning: multiplex molecular analysis of diverse life science platforms. Clinica chimica acta; international journal of clinical chemistry\| PubMed ID: 16996046	2007
Optimization of recovery of RNA from formalin-fixed, paraffin-embedded tissue. Diagnostic molecular pathology : the American journal of surgical pathology, part B\| PubMed ID: 17122651	2006
Variation in breast cancer hormone receptor and HER2 levels by etiologic factors: a population-based analysis. International journal of cancer\| PubMed ID: 17487843	2007
Tissue microarrays enabling high-throughput molecular pathology. Current opinion in biotechnology\| PubMed ID: 17643281	2007
Liver proteomics for therapeutic drug discovery: inhibition of the cyclophilin receptor CD147 attenuates sepsis-induced acute renal failure. Critical care medicine\| PubMed ID: 17944020	2007
The ubiquitin ligase gp78 promotes sarcoma metastasis by targeting KAI1 for degradation. Nature medicine\| PubMed ID: 18037895	2007
Pharmacodynamic assessment of histone deacetylase inhibitors: infrared vibrational spectroscopic imaging of protein acetylation. Analytical chemistry\| PubMed ID: 18651756	2008
Factors in tissue handling and processing that impact RNA obtained from formalin-fixed, paraffin-embedded tissue. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society\| PubMed ID: 18711211	2008
Tissue handling and specimen preparation in surgical pathology: issues concerning the recovery of nucleic acids from formalin-fixed, paraffin-embedded tissue. Archives of pathology & laboratory medicine\| PubMed ID: 19061293	2008
DNA methylation represses IFN-gamma-induced and signal transducer and activator of transcription 1-mediated IFN regulatory factor 8 activation in colon carcinoma cells. Molecular cancer research : MCR\| PubMed ID: 19074829	2008
Wnt5A regulates expression of tumor-associated antigens in melanoma via changes in signal transducers and activators of transcription 3 phosphorylation. Cancer research\| PubMed ID: 19074888	2008
Acute Kidney Injury Biomarkers - Needs, Present Status, and Future Promise. Nephrology self-assessment program : NephSAP\| PubMed ID: 19096722	2006
Automated quantitative assessment of HER-2/neu immunohistochemical expression in breast cancer. IEEE transactions on medical imaging\| PubMed ID: 19164073	2009
Sperm-derived SPANX-B is a clinically relevant tumor antigen that is expressed in human tumors and readily recognized by human CD4+ and CD8+ T cells. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19276289	2009
Tissue microarrays as a tool in the discovery and validation of tumor markers. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19381953	2009
Cytokeratin immunoexpression in esophageal squamous cell carcinoma of high-risk population in Northeast India. Applied immunohistochemistry & molecular morphology : AIMM\| PubMed ID: 19417629	2009
DEAR1 is a dominant regulator of acinar morphogenesis and an independent predictor of local recurrence-free survival in early-onset breast cancer. PLoS medicine\| PubMed ID: 19536326	2009
NRG1 / ERBB3 signaling in melanocyte development and melanoma: inhibition of differentiation and promotion of proliferation. Pigment cell & melanoma research\| PubMed ID: 19659570	2009
The chemokine CXCL16 and its receptor, CXCR6, as markers and promoters of inflammation-associated cancers. PloS one\| PubMed ID: 19690611	2009
Biomarkers of apoptosis and survival in esophageal squamous cell carcinoma. BMC cancer\| PubMed ID: 19728877	2009
The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma. Oncogene\| PubMed ID: 19802008	2010
An optimized RNA extraction method from archival formalin-fixed paraffin-embedded tissue. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19960319	2010
Assessment of automated image analysis of breast cancer tissue microarrays for epidemiologic studies. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology\| PubMed ID: 20332278	2010
Histo-proteomic profiling of formalin-fixed, paraffin-embedded tissue. Expert review of proteomics\| PubMed ID: 20377389	2010
Glucose transporter Glut-1 is detectable in peri-necrotic regions in many human tumor types but not normal tissues: Study using tissue microarrays. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft\| PubMed ID: 20395120	2010
Immunoguided laser assisted microdissection techniques for DNA methylation analysis of archival tissue specimens. The Journal of molecular diagnostics : JMD\| PubMed ID: 20413681	2010
Multiple endocrine neoplasia type 1 deletion in pancreatic alpha-cells leads to development of insulinomas in mice. Endocrinology\| PubMed ID: 20555035	2010
Modeling metastasis biology and therapy in real time in the mouse lung. The Journal of clinical investigation\| PubMed ID: 20644255	2010
Podoplanin expression in cancerous stroma induces lymphangiogenesis and predicts lymphatic spread and patient survival. Archives of pathology & laboratory medicine\| PubMed ID: 20923309	2010
Loss of Klotho during melanoma progression leads to increased filamin cleavage, increased Wnt5A expression, and enhanced melanoma cell motility. Pigment cell & melanoma research\| PubMed ID: 20955350	2011
Proteomic expression profiling of thyroid neoplasms. Proteomics. Clinical applications\| PubMed ID: 21136677	2007
Validation of proteomic-based discovery with tissue microarrays. Proteomics. Clinical applications\| PubMed ID: 21136794	2008
A well-based reverse-phase protein array applicable to extracts from formalin-fixed paraffin-embedded tissue. Proteomics. Clinical applications\| PubMed ID: 21136801	2008
Characterizations and validations of novel antibodies toward translational research. Proteomics. Clinical applications\| PubMed ID: 21137080	2010
Observer variability in the interpretation of HER2/neu immunohistochemical expression with unaided and computer-aided digital microscopy. Archives of pathology & laboratory medicine\| PubMed ID: 21284444	2011
Multimodal microscopy for automated histologic analysis of prostate cancer. BMC cancer\| PubMed ID: 21303560	2011
Factors influencing the degradation of archival formalin-fixed paraffin-embedded tissue sections. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society\| PubMed ID: 21411807	2011
Methylation profiling of mediastinal gray zone lymphoma reveals a distinctive signature with elements shared by classical Hodgkin's lymphoma and primary mediastinal large B-cell lymphoma. Haematologica\| PubMed ID: 21454882	2011
Downregulation of Filamin A interacting protein 1-like is associated with promoter methylation and induces an invasive phenotype in ovarian cancer. Molecular cancer research : MCR\| PubMed ID: 21693594	2011
Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma. Journal of translational medicine\| PubMed ID: 21801427	2011
Gray zone lymphoma: chromosomal aberrations with immunophenotypic and clinical correlations. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc\| PubMed ID: 21822207	2011
Wilms tumor-1, claudin-1 and ezrin are useful immunohistochemical markers that help to distinguish schwannoma from fibroblastic meningioma. Pathology oncology research : POR\| PubMed ID: 21909685	2012
Evaluation of eIF4E expression in an osteosarcoma-specific tissue microarray. Journal of pediatric hematology/oncology\| PubMed ID: 21941146	2011
Tissue microarrays as a tool in the discovery and validation of predictive biomarkers. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 22081347	2012
The role of secreted frizzled-related protein 2 expression in prostate cancer. Histopathology\| PubMed ID: 22175903	2011
Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group. NPJ breast cancer\| PubMed ID: 32411818	2020
Impact of preanalytic factors on the design and application of integral biomarkers for directing patient therapy. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 22422404	2012
A pressure cooking-based DNA extraction from archival formalin-fixed, paraffin-embedded tissue. Analytical biochemistry\| PubMed ID: 22449494	2012
Analysis of terminal duct lobular unit involution in luminal A and basal breast cancers. Breast cancer research : BCR\| PubMed ID: 22513288	2012
Human CCR4+ CCR6+ Th17 cells suppress autologous CD8+ T cell responses. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 22615204	2012
Gene expression and epigenetic discovery screen reveal methylation of SFRP2 in prostate cancer. International journal of cancer\| PubMed ID: 22915211	2013
Image microarrays derived from tissue microarrays (IMA-TMA): New resource for computer-aided diagnostic algorithm development. Journal of pathology informatics\| PubMed ID: 22934237	2012
HER3 overexpression is a prognostic indicator of extrahepatic cholangiocarcinoma. Virchows Archiv : an international journal of pathology\| PubMed ID: 23052372	2012
Synaptonemal complex protein 3 as a novel prognostic marker in early stage non-small cell lung cancer. Human pathology\| PubMed ID: 23069255	2013
Follicular lymphomas in children and young adults: a comparison of the pediatric variant with usual follicular lymphoma. The American journal of surgical pathology\| PubMed ID: 23108024	2013
Genetic variant as a selection marker for anti-prostate stem cell antigen immunotherapy of bladder cancer. Journal of the National Cancer Institute\| PubMed ID: 23266392	2013
Estrogen receptor and progesterone receptor expression in normal terminal duct lobular units surrounding invasive breast cancer. Breast cancer research and treatment\| PubMed ID: 23271326	2013
Digital pathology evaluation in the multicenter Nephrotic Syndrome Study Network (NEPTUNE). Clinical journal of the American Society of Nephrology : CJASN\| PubMed ID: 23393107	2013
Functional activity and tumor-specific expression of dual oxidase 2 in pancreatic cancer cells and human malignancies characterized with a novel monoclonal antibody. International journal of oncology\| PubMed ID: 23404210	2013
Improved survival of gastric cancer with tumour Epstein-Barr virus positivity: an international pooled analysis. Gut\| PubMed ID: 23580779	2014
Characterization of NADPH oxidase 5 expression in human tumors and tumor cell lines with a novel mouse monoclonal antibody. Free radical biology & medicine\| PubMed ID: 23851018	2013
Prognostic assessment of hypoxia and metabolic markers in cervical cancer using automated digital image analysis of immunohistochemistry. Journal of translational medicine\| PubMed ID: 23927384	2013
Reproducibility in the automated quantitative assessment of HER2/neu for breast cancer. Journal of pathology informatics\| PubMed ID: 23967384	2013
Validation of esophageal squamous cell carcinoma candidate genes from high-throughput transcriptomic studies. American journal of cancer research\| PubMed ID: 23977449	2013
Breast cancer susceptibility risk associations and heterogeneity by E-cadherin tumor tissue expression. Breast cancer research and treatment\| PubMed ID: 24292867	2014
Expression of stress-induced phosphoprotein1 (STIP1) is associated with tumor progression and poor prognosis in epithelial ovarian cancer. Genes, chromosomes & cancer\| PubMed ID: 24488757	2014
CLPTM1L promotes growth and enhances aneuploidy in pancreatic cancer cells. Cancer research\| PubMed ID: 24648346	2014
PLCE1 mRNA and protein expression and survival of patients with esophageal squamous cell carcinoma and gastric adenocarcinoma. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology\| PubMed ID: 24867265	2014
Assessment of vascular endothelial growth factor in formalin fixed, paraffin embedded colon cancer specimens by means of a well-based reverse phase protein array. Proteome science\| PubMed ID: 24883046	2014
Synaptonemal complex protein 3 is a prognostic marker in cervical cancer. PloS one\| PubMed ID: 24905095	2014
The role of S100A14 in epithelial ovarian tumors. Oncotarget\| PubMed ID: 24939856	2014
microRNA alterations driving acute and late stages of radiation-induced fibrosis in a murine skin model. International journal of radiation oncology, biology, physics\| PubMed ID: 24986745	2014
Controls for immunohistochemistry: the Histochemical Society's standards of practice for validation of immunohistochemical assays. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society\| PubMed ID: 25023613	2014
Improving the state of the science of immunohistochemistry: the Histochemical Society's standards of practice. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society\| PubMed ID: 25085896	2014
The 19q12 bladder cancer GWAS signal: association with cyclin E function and aggressive disease. Cancer research\| PubMed ID: 25320178	2014
MICA/B and ULBP1 NKG2D ligands are independent predictors of good prognosis in cervical cancer. BMC cancer\| PubMed ID: 25510288	2014
Greater absolute risk for all subtypes of breast cancer in the US than Malaysia. Breast cancer research and treatment\| PubMed ID: 25537643	2015
The evolution of pre-analytic factors in Anatomic Pathology. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer\| PubMed ID: 25636426	2015
Expression of stanniocalcin 1 in thyroid side population cells and thyroid cancer cells. Thyroid : official journal of the American Thyroid Association\| PubMed ID: 25647164	2015
Cell-cycle protein expression in a population-based study of ovarian and endometrial cancers. Frontiers in oncology\| PubMed ID: 25709969	2015
Observer performance in the use of digital and optical microscopy for the interpretation of tissue-based biomarkers. Analytical cellular pathology (Amsterdam)\| PubMed ID: 25763314	2014
Evaluating whole slide imaging: A working group opportunity. Journal of pathology informatics\| PubMed ID: 25774315	2015
CDK4 Amplification Reduces Sensitivity to CDK4/6 Inhibition in Fusion-Positive Rhabdomyosarcoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 25810375	2015
HER-2 assessment in formalin-fixed paraffin-embedded breast cancer tissue by well-based reverse phase protein array. Clinical proteomics\| PubMed ID: 25838812	2014
Pancreatic adenocarcinoma up-regulated factor expression is associated with disease-specific survival in cervical cancer patients. Human pathology\| PubMed ID: 25870121	2015
Assessment of a panel of tumor markers for the differential diagnosis of benign and malignant effusions by well-based reverse phase protein array. Diagnostic pathology\| PubMed ID: 26022333	2015
Stain-less staining for computed histopathology. Technology\| PubMed ID: 26029735	2015
A well-based reverse-phase protein array of formalin-fixed paraffin-embedded tissue. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 26043998	2015
Proteomic expressional profiling of a paraffin-embedded tissue by multiplex tissue immunoblotting. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 26044002	2015
Evaluation environment for digital and analog pathology: a platform for validation studies. Journal of medical imaging (Bellingham, Wash.)\| PubMed ID: 26158076	2014
Prognostic Significance of AMP-Dependent Kinase Alpha Expression in Cervical Cancer. Pathobiology : journal of immunopathology, molecular and cellular biology\| PubMed ID: 26337566	2015
A Novel Quantitative Multiplex Tissue Immunoblotting for Biomarkers Predicts a Prostate Cancer Aggressive Phenotype. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology\| PubMed ID: 26404961	2015
Relationship of Terminal Duct Lobular Unit Involution of the Breast with Area and Volume Mammographic Densities. Cancer prevention research (Philadelphia, Pa.)\| PubMed ID: 26645278	2016
Clinical significance of OCT4 and SOX2 protein expression in cervical cancer. BMC cancer\| PubMed ID: 26706028	2015
The TRAIL receptor agonist drozitumab targets basal B triple-negative breast cancer cells that express vimentin and Axl. Breast cancer research and treatment\| PubMed ID: 26759246	2016
Circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3 and terminal duct lobular unit involution of the breast: a cross-sectional study of women with benign b... Breast cancer research : BCR\| PubMed ID: 26893016	2016
Targeting a Cancer-Specific Epitope of the Epidermal Growth Factor Receptor in Triple-Negative Breast Cancer. Journal of the National Cancer Institute\| PubMed ID: 27075852	2016
Expression of fibroblast growth factor receptor family members is associated with prognosis in early stage cervical cancer patients. Journal of translational medicine\| PubMed ID: 27154171	2016
A Buffered Alcohol-Based Fixative for Histomorphologic and Molecular Applications. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society\| PubMed ID: 27221702	2016
Automated prostate tissue referencing for cancer detection and diagnosis. BMC bioinformatics\| PubMed ID: 27247129	2016
The Application of Digital Pathology to Improve Accuracy in Glomerular Enumeration in Renal Biopsies. PloS one\| PubMed ID: 27310011	2016
Prognostic significance of annexin A2 and annexin A4 expression in patients with cervical cancer. BMC cancer\| PubMed ID: 27402115	2016
A melanin-bleaching methodology for molecular and histopathological analysis of formalin-fixed paraffin-embedded tissue. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 27548802	2016
Relationships between mammographic density, tissue microvessel density, and breast biopsy diagnosis. Breast cancer research : BCR\| PubMed ID: 27552842	2016
Reduced expression of FILIP1L, a novel WNT pathway inhibitor, is associated with poor survival, progression and chemoresistance in ovarian cancer. Oncotarget\| PubMed ID: 27776341	2016
Relationship between crown-like structures and sex-steroid hormones in breast adipose tissue and serum among postmenopausal breast cancer patients. Breast cancer research : BCR\| PubMed ID: 28103902	2017
PAX3-FOXO1 is essential for tumour initiation and maintenance but not recurrence in a human myoblast model of rhabdomyosarcoma. The Journal of pathology\| PubMed ID: 28138962	2017
Computational analysis of the mesenchymal signature landscape in gliomas. BMC medical genomics\| PubMed ID: 28279210	2017
Multiview boosting digital pathology analysis of prostate cancer. Computer methods and programs in biomedicine\| PubMed ID: 28325451	2017
Interstitial fibrosis scored on whole-slide digital imaging of kidney biopsies is a predictor of outcome in proteinuric glomerulopathies. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association\| PubMed ID: 28339906	2018
Editor's Note. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society\| PubMed ID: 28347263	2017
Formulation and pH of the Buffered Ethanol Fixative BE70. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society\| PubMed ID: 28347266	2017
Synaptonemal complex protein 3 is associated with lymphangiogenesis in non-small cell lung cancer patients with lymph node metastasis. Journal of translational medicine\| PubMed ID: 28623914	2017
The Impact Factor Is a 20th-Century Relic in an Electronic Journal World of Instant Citation Counts. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society\| PubMed ID: 28651472	2017
HDAC1 Upregulation by NANOG Promotes Multidrug Resistance and a Stem-like Phenotype in Immune Edited Tumor Cells. Cancer research\| PubMed ID: 28716899	2017
Therapeutically targeting glypican-2 via single-domain antibody-based chimeric antigen receptors and immunotoxins in neuroblastoma. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 28739923	2017
The anti-cancer effects of itraconazole in epithelial ovarian cancer. Scientific reports\| PubMed ID: 28747628	2017
eeDAP: An Evaluation Environment for Digital and Analog Pathology. Proceedings of SPIE--the International Society for Optical Engineering\| PubMed ID: 28845079	2014
Bcl-2-like Protein 11 (BIM) Expression Is Associated with Favorable Prognosis for Patients with Cervical Cancer. Anticancer research\| PubMed ID: 28870908	2017
Histomorphological and Molecular Assessments of the Fixation Times Comparing Formalin and Ethanol-Based Fixatives. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society\| PubMed ID: 29125916	2018
Aberrant tRNA processing causes an autoinflammatory syndrome responsive to TNF inhibitors. Annals of the rheumatic diseases\| PubMed ID: 29358286	2018
Urine: Waste product or biologically active tissue? Neurourology and urodynamics\| PubMed ID: 29464759	2018
Oncogene-induced senescence mediated by c-Myc requires USP10 dependent deubiquitination and stabilization of p14ARF. Cell death and differentiation\| PubMed ID: 29472714	2018
RE: Elevated Bladder Cancer in Northern New England: The Role of Drinking Water and Arsenic. Journal of the National Cancer Institute\| PubMed ID: 29548022	2018
Clinically Relevant Cytotoxic Immune Cell Signatures and Clonal Expansion of T-Cell Receptors in High-Risk -Not-Amplified Human Neuroblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 29784674	2018
A multiprotein supercomplex controlling oncogenic signalling in lymphoma. Nature\| PubMed ID: 29925955	2018
Elevated expression of pancreatic adenocarcinoma upregulated factor (PAUF) is associated with poor prognosis and chemoresistance in epithelial ovarian cancer. Scientific reports\| PubMed ID: 30111860	2018
Genomic Network-Based Analysis Reveals Pancreatic Adenocarcinoma Up-Regulating Factor-Related Prognostic Markers in Cervical Carcinoma. Frontiers in oncology\| PubMed ID: 30406031	2018
APOL1 risk allele RNA contributes to renal toxicity by activating protein kinase R. Communications biology\| PubMed ID: 30417125	2018
Immunophenotypic Characterization of Canine Splenic Follicular-Derived B-Cell Lymphoma. Veterinary pathology\| PubMed ID: 30636524	2019
APOBEC Mutagenesis and Copy-Number Alterations Are Drivers of Proteogenomic Tumor Evolution and Heterogeneity in Metastatic Thoracic Tumors. Cell reports\| PubMed ID: 30840888	2019
Combination immunotherapy with IL-4 Pseudomonas exotoxin and IFN-α and IFN-γ mediate antitumor effects in vitro and in a mouse model of human ovarian cancer. Immunotherapy\| PubMed ID: 30860437	2019
Hepatitis B Surface Antigen Activates Unfolded Protein Response in Forming Ground Glass Hepatocytes of Chronic Hepatitis B. Viruses\| PubMed ID: 31027244	2019
A mouse model of Proteus syndrome. Human molecular genetics\| PubMed ID: 31194862	2019
Forkhead box protein O1 (FOXO1) and paired box gene 3 (PAX3) overexpression is associated with poor prognosis in patients with cervical cancer. International journal of clinical oncology\| PubMed ID: 31302815	2019
Agreement in Histological Assessment of Mitotic Activity Between Microscopy and Digital Whole Slide Images Informs Conversion for Clinical Diagnosis. Academic pathology\| PubMed ID: 31321298	2019
A Pilot Study of Sirolimus in Subjects with Cowden Syndrome or Other Syndromes Characterized by Germline Mutations in . The oncologist\| PubMed ID: 31350329	2019
T-Cell Receptor Gene Therapy for Human Papillomavirus-Associated Epithelial Cancers: A First-in-Human, Phase I/II Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 31408414	2019
Deubiquitylation and stabilization of Notch1 intracellular domain by ubiquitin-specific protease 8 enhance tumorigenesis in breast cancer. Cell death and differentiation\| PubMed ID: 31527799	2020
Enlightening kidney pathophysiology. Nature materials\| PubMed ID: 31537941	2019
ALDH1A2 Is a Candidate Tumor Suppressor Gene in Ovarian Cancer. Cancers\| PubMed ID: 31615043	2019
Efficacy and tolerability of anti-programmed death-ligand 1 (PD-L1) antibody (Avelumab) treatment in advanced thymoma. Journal for immunotherapy of cancer\| PubMed ID: 31639039	2019
CDK7 is a reliable prognostic factor and novel therapeutic target in epithelial ovarian cancer. Gynecologic oncology\| PubMed ID: 31776040	2020
Diesel exhaust and bladder cancer risk by pathologic stage and grade subtypes. Environment international\| PubMed ID: 31864026	2020
Racial Differences in the Association Between Luminal Master Regulator Gene Expression Levels and Breast Cancer Survival. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 31911546	2020
Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis. Nature communications\| PubMed ID: 31949145	2020
HSP90A inhibition promotes anti-tumor immunity by reversing multi-modal resistance and stem-like property of immune-refractory tumors. Nature communications\| PubMed ID: 31992715	2020
Persistent Polyfunctional Chimeric Antigen Receptor T Cells That Target Glypican 3 Eliminate Orthotopic Hepatocellular Carcinomas in Mice. Gastroenterology\| PubMed ID: 32060001	2020
Chemoradiotherapy response prediction model by proteomic expressional profiling in patients with locally advanced cervical cancer. Gynecologic oncology\| PubMed ID: 32107047	2020
The Challenges of Optimizing Biomarkers to Guide Clinical Decision Making. Journal of the National Cancer Institute\| PubMed ID: 32129860	2020
Identification of Candidate Genes Associated with Susceptibility to Ovarian Clear Cell Adenocarcinoma Using -eQTL Analysis. Journal of clinical medicine\| PubMed ID: 32316112	2020
Low Epstein-Barr Virus Prevalence in Cardia Gastric Cancer Among a High-Incidence Chinese Population. Digestive diseases and sciences\| PubMed ID: 32367248	2021
LC3B upregulation by NANOG promotes immune resistance and stem-like property through hyperactivation of EGFR signaling in immune-refractory tumor cells. Autophagy\| PubMed ID: 32762616	2021
Development and evaluation of deep learning-based segmentation of histologic structures in the kidney cortex with multiple histologic stains. Kidney international\| PubMed ID: 32835732	2021
4-HNE Immunohistochemistry and Image Analysis for Detection of Lipid Peroxidation in Human Liver Samples Using Vitamin E Treatment in NAFLD as a Proof of Concept. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society\| PubMed ID: 32867573	2020
Loss of HES-1 Expression Predicts a Poor Prognosis for Small Intestinal Adenocarcinoma Patients. Frontiers in oncology\| PubMed ID: 32974155	2020
In Utero Severe Acute Respiratory Syndrome Coronavirus 2 Infection. Journal of the Pediatric Infectious Diseases Society\| PubMed ID: 33089311	2020
Prognostic implication of SOX2 expression in small intestinal adenocarcinoma. Virchows Archiv : an international journal of pathology\| PubMed ID: 33103210	2021
Development of CAR T Cells Expressing a Suicide Gene Plus a Chimeric Antigen Receptor Targeting Signaling Lymphocytic-Activation Molecule F7. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 33129371	2021
Tumor-associated macrophage, angiogenesis and lymphangiogenesis markers predict prognosis of non-small cell lung cancer patients. Journal of translational medicine\| PubMed ID: 33228719	2020
IGF-1 Receptor Signaling Regulates Type II Pneumocyte Senescence and Resulting Macrophage Polarization in Lung Fibrosis. International journal of radiation oncology, biology, physics\| PubMed ID: 33385497	2021
Network for Biomarker Immunoprofiling for Cancer Immunotherapy: Cancer Immune Monitoring and Analysis Centers and Cancer Immunologic Data Commons (CIMAC-CIDC). Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 33419780	2021
MEK/ERK signaling is a critical regulator of high-risk human papillomavirus oncogene expression revealing therapeutic targets for HPV-induced tumors. PLoS pathogens\| PubMed ID: 33481911	2021
Kaiso (ZBTB33) subcellular partitioning functionally links LC3A/B, the tumor microenvironment, and breast cancer survival. Communications biology\| PubMed ID: 33526872	2021
SARS-CoV-2 infection of the oral cavity and saliva. Nature medicine\| PubMed ID: 33767405	2021
Crosstalk between WNT and STAT3 is mediated by galectin-3 in tumor progression. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association\| PubMed ID: 33834359	2021
Improving data quality in observational research studies: Report of the Cure Glomerulonephropathy (CureGN) network. Contemporary clinical trials communications\| PubMed ID: 33851061	2021
Clinical Significance of Tumor Infiltrating Lymphocytes in Association with Hormone Receptor Expression Patterns in Epithelial Ovarian Cancer. International journal of molecular sciences\| PubMed ID: 34071938	2021
CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice. Cell reports. Medicine\| PubMed ID: 34195677	2021
Regulates Chemoresistance in Association With by Inhibiting Apoptosis Pathway in Patients With Cervical Cancer. Cancer genomics & proteomics\| PubMed ID: 34697063	2021
Spatial mapping of protein composition and tissue organization: a primer for multiplexed antibody-based imaging. Nature methods\| PubMed ID: 34811556	2022
Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation. Science immunology\| PubMed ID: 34932384	2021
Evidence of SARS-CoV-2-Specific T-Cell-Mediated Myocarditis in a MIS-A Case. Frontiers in immunology\| PubMed ID: 34956207	2021
Multicenter analysis of neutrophil extracellular trap dysregulation in adult and pediatric COVID-19. medRxiv : the preprint server for health sciences\| PubMed ID: 35262093	2022
Reproducible, high-dimensional imaging in archival human tissue by multiplexed ion beam imaging by time-of-flight (MIBI-TOF). Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 35351966	2022
Locoregional tumor burden and risk of mortality in metastatic breast cancer. NPJ precision oncology\| PubMed ID: 35383277	2022
Prevalence and Mechanisms of Mucus Accumulation in COVID-19 Lung Disease. American journal of respiratory and critical care medicine\| PubMed ID: 35816430	2022
Precocious Puberty in a Boy With Bilateral Leydig Cell Tumors due to a Somatic Gain-of-Function Variant. Journal of the Endocrine Society\| PubMed ID: 36111273	2022
The role of FXR and TGR5 in reversing and preventing progression of Western diet-induced hepatic steatosis, inflammation, and fibrosis in mice. The Journal of biological chemistry\| PubMed ID: 36209823	2022
Quality Assessment of Proteins and RNA Following Storage in Archival Formalin-Fixed Paraffin-Embedded Human Breast Cancer Tissue Microarray Sections. Biopreservation and biobanking\| PubMed ID: 36264172	2023
Variant APOL1 protein in plasma associates with larger particles in humans and mouse models of kidney injury. PloS one\| PubMed ID: 36279295	2022
Systemic Nos2 Depletion and Cox inhibition limits TNBC disease progression and alters lymphoid cell spatial orientation and density. Redox biology\| PubMed ID: 36375380	2022
SARS-CoV-2 infection and persistence in the human body and brain at autopsy. Nature\| PubMed ID: 36517603	2022
Cell-specific cargo delivery using synthetic bacterial spores. Cell reports\| PubMed ID: 36640333	2023
Successful lung transplantation using an allograft from a COVID-19-recovered donor: a potential role for subgenomic RNA to guide organ utilization. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 36695611	2023
Extrachromosomal DNA Amplification Contributes to Small Cell Lung Cancer Heterogeneity and Is Associated with Worse Outcomes. Cancer discovery\| PubMed ID: 36715552	2023
Phase I/II study of PexaVec in combination with immune checkpoint inhibition in refractory metastatic colorectal cancer. Journal for immunotherapy of cancer\| PubMed ID: 36754451	2023
Scaffolding Protein Connector Enhancer of Kinase Suppressor of Ras 1 (CNKSR1) Regulates MAPK Inhibition Responsiveness in Pancreas Cancer via Crosstalk with AKT Signaling. Molecular cancer research : MCR\| PubMed ID: 36790955	2023
The Application of Guanidinium to Improve Biomolecule Quality in Fixed, Paraffin-embedded Tissue. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society\| PubMed ID: 36869703	2023
Constitutively active Lyn kinase causes a cutaneous small vessel vasculitis and liver fibrosis syndrome. Nature communications\| PubMed ID: 36932076	2023
Histopathology and SARS-CoV-2 Cellular Localization in Eye Tissues of COVID-19 Autopsies. The American journal of pathology\| PubMed ID: 36963628	2023
The IgG4 hinge with CD28 transmembrane domain improves VH-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer. Nature communications\| PubMed ID: 37031249	2023
Interferon-gamma is quintessential for NOS2 and COX2 expression in ER breast tumors that lead to poor outcome. Cell death & disease\| PubMed ID: 37169743	2023
Tumor biology and immune infiltration define primary liver cancer subsets linked to overall survival after immunotherapy. Cell reports. Medicine\| PubMed ID: 37224815	2023
Clinical and biological heterogeneity of multisystem inflammatory syndrome in adults following SARS-CoV-2 infection: a case series. Frontiers in medicine\| PubMed ID: 37484839	2023
Pulmonary Co-Infections Detected Premortem Underestimate Postmortem Findings in a COVID-19 Autopsy Case Series. Pathogens (Basel, Switzerland)\| PubMed ID: 37513779	2023
NOS2 and COX2 Provide Key Spatial Targets that Determine Outcome in ER- Breast Cancer. bioRxiv : the preprint server for biology\| PubMed ID: 38187532	2023
Spatial analysis of NOS2 and COX2 interaction with T-effector cells reveals immunosuppressive landscapes associated with poor outcome in ER- breast cancer patients. bioRxiv : the preprint server for biology\| PubMed ID: 38187660	2023
ATOH1, TFAP2B, and CEACAM6 as Immunohistochemical Markers to Distinguish Merkel Cell Carcinoma and Small Cell Lung Cancer. Cancers\| PubMed ID: 38398178	2024
SARS-CoV-2 Infection of Salivary Glands Compromises Oral Antifungal Innate Immunity and Predisposes to Oral Candidiasis. bioRxiv : the preprint server for biology\| PubMed ID: 38798323	2024
Spatial Deconvolution of Cell Types and Cell States at Scale Utilizing TACIT. bioRxiv : the preprint server for biology\| PubMed ID: 38895230	2024
Contribution of Prediagnostic Host Factors to Shaping the Stromal Microenvironment of Breast Cancer among Sub-Saharan African Women. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology\| PubMed ID: 38958945	2025
Spatial Deconvolution of Cell Types and Cell States at Scale Utilizing TACIT. Research square\| PubMed ID: 38978567	2024
Initiator cell death event induced by SARS-CoV-2 in the human airway epithelium. Science immunology\| PubMed ID: 38996010	2024
Glypican-3 deficiency in liver cancer upregulates MAPK/ERK pathway but decreases cell proliferation. American journal of cancer research\| PubMed ID: 39113871	2024
Tumor NOS2 and COX2 Spatial Juxtaposition with CD8+ T Cells Promote Metastatic and Cancer Stem Cell Niches that Lead to Poor Outcome in ER- Breast Cancer. Cancer research communications\| PubMed ID: 39356141	2024
SARS-CoV-2 infection of salivary glands compromises the production of a secreted antifungal peptide with potential implications for development of oral candidiasis. PLoS pathogens\| PubMed ID: 39666753	2024
Targeting the SARS-CoV-2 reservoir in long COVID. The Lancet. Infectious diseases\| PubMed ID: 39947217	2025
Deconvolution of cell types and states in spatial multiomics utilizing TACIT. Nature communications\| PubMed ID: 40258827	2025
Clinicopathologic Features, Management, and Outcomes Of Pediatric CRTC1::TRIM11 and MED15::ATF1 Tumors With Spitzoid Morphology: A Case Series. Pediatric blood & cancer\| PubMed ID: 40390195	2025