James Broach

Department of Molecular Biology, Princeton University

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 17	2006
Publication title Cited by 4	2006

Other Publications

Article	Year
A point mutation that confers constitutive activity to CXCR4 reveals that T140 is an inverse agonist and that AMD3100 and ALX40-4C are weak partial agonists. The Journal of biological chemistry\| PubMed ID: 11923301	2002
Directional bias during mating type switching in Saccharomyces is independent of chromosomal architecture. The EMBO journal\| PubMed ID: 11980725	2002
Rap1p and other transcriptional regulators can function in defining distinct domains of gene expression. Nucleic acids research\| PubMed ID: 12582242	2003
Making good neighbors: the right fence for the right job. Nature structural biology\| PubMed ID: 12660719	2003
Multiple roles of Tap42 in mediating rapamycin-induced transcriptional changes in yeast. Molecular cell\| PubMed ID: 12820961	2003
Constitutive activation of CCR5 and CCR2 induced by conformational changes in the conserved TXP motif in transmembrane helix 2. The Journal of biological chemistry\| PubMed ID: 12837756	2003
Molecular-size reduction of a potent CXCR4-chemokine antagonist using orthogonal combination of conformation- and sequence-based libraries. Angewandte Chemie (International ed. in English)\| PubMed ID: 12876735	2003
Theoretical and computational studies of the glucose signaling pathways in yeast using global gene expression data. Biotechnology and bioengineering\| PubMed ID: 14708127	2003
The Ras/protein kinase A pathway acts in parallel with the Mob2/Cbk1 pathway to effect cell cycle progression and proper bud site selection. Eukaryotic cell\| PubMed ID: 14871942	2004
Metastin and its variant forms suppress migration of pancreatic cancer cells. Biochemical and biophysical research communications\| PubMed ID: 15013429	2004
The Saccharomyces cerevisiae recombination enhancer biases recombination during interchromosomal mating-type switching but not in interchromosomal homologous recombination. Genetics\| PubMed ID: 15082540	2004
Ras and Gpa2 mediate one branch of a redundant glucose signaling pathway in yeast. PLoS biology\| PubMed ID: 15138498	2004
A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size. Genes & development\| PubMed ID: 15466158	2004
PP2A phosphatase activity is required for stress and Tor kinase regulation of yeast stress response factor Msn2p. Eukaryotic cell\| PubMed ID: 15470255	2004
Making the right choice--long-range chromosomal interactions in development. Cell\| PubMed ID: 15550239	2004
Sense and sensibility: nutritional response and signal integration in yeast. Current opinion in microbiology\| PubMed ID: 15556035	2004
Mutations in the nucleosome core enhance transcriptional silencing. Molecular and cellular biology\| PubMed ID: 15713639	2005
Design and synthesis of downsized metastin (45-54) analogs with maintenance of high GPR54 agonistic activity. Bioorganic & medicinal chemistry letters\| PubMed ID: 16242330	2006
Creation of GPCR-based chemical sensors by directed evolution in yeast. Protein engineering, design & selection : PEDS\| PubMed ID: 16263727	2006
The dynamics of homologous pairing during mating type interconversion in budding yeast. PLoS genetics\| PubMed ID: 16789829	2006
Single-cell observations reveal intermediate transcriptional silencing states. Molecular cell\| PubMed ID: 16857588	2006
Functional expression of CXCR4 in Saccharomyces cerevisiae in the development of powerful tools for the pharmacological characterization of CXCR4. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 16878688	2006
Cross-talk and decision making in MAP kinase pathways. Nature genetics\| PubMed ID: 17259986	2007
Sch9 is a major target of TORC1 in Saccharomyces cerevisiae. Molecular cell\| PubMed ID: 17560372	2007
Protein kinase A and Sch9 cooperatively regulate induction of autophagy in Saccharomyces cerevisiae. Molecular biology of the cell\| PubMed ID: 17699586	2007
Evaluation of normalization and pre-clustering issues in a novel clustering approach: global optimum search with enhanced positioning. Journal of bioinformatics and computational biology\| PubMed ID: 17787062	2007
How Saccharomyces responds to nutrients. Annual review of genetics\| PubMed ID: 18303986	2008
Microarray data mining: a novel optimization-based approach to uncover biologically coherent structures. BMC bioinformatics\| PubMed ID: 18538024	2008
Ph.D. Training in cancer biology. Cancer research\| PubMed ID: 19010881	2008
Predicting cellular growth from gene expression signatures. PLoS computational biology\| PubMed ID: 19119411	2009
Glucose regulates transcription in yeast through a network of signaling pathways. Molecular systems biology\| PubMed ID: 19225458	2009
Microarray profiling of phage-display selections for rapid mapping of transcription factor-DNA interactions. PLoS genetics\| PubMed ID: 19360118	2009
Expression of CXCR4, a G-protein-coupled receptor for CXCL12 in yeast identification of new-generation inverse agonists. Methods in enzymology\| PubMed ID: 19446737	2009
Chromatin-dependent transcription factor accessibility rather than nucleosome remodeling predominates during global transcriptional restructuring in Saccharomyces cerevisiae. Molecular biology of the cell\| PubMed ID: 19494041	2009
Protein kinase A and TORC1 activate genes for ribosomal biogenesis by inactivating repressors encoded by Dot6 and its homolog Tod6. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19901341	2009
The origin recognition complex interacts with a subset of metabolic genes tightly linked to origins of replication. PLoS genetics\| PubMed ID: 19997491	2009
Initiation of the TORC1-regulated G0 program requires Igo1/2, which license specific mRNAs to evade degradation via the 5'-3' mRNA decay pathway. Molecular cell\| PubMed ID: 20471941	2010
Yeast cells can access distinct quiescent states. Genes & development\| PubMed ID: 21289062	2011
Chromatin remodelers clear nucleosomes from intrinsically unfavorable sites to establish nucleosome-depleted regions at promoters. Molecular biology of the cell\| PubMed ID: 21508315	2011
Decoding complex chemical mixtures with a physical model of a sensor array. PLoS computational biology\| PubMed ID: 22046111	2011
Regulation of yeast pyruvate kinase by ultrasensitive allostery independent of phosphorylation. Molecular cell\| PubMed ID: 22902555	2012
High hydrostatic pressure activates gene expression that leads to ethanol production enhancement in a Saccharomyces cerevisiae distillery strain. Applied microbiology and biotechnology\| PubMed ID: 22915193	2013
Nutritional control of growth and development in yeast. Genetics\| PubMed ID: 22964838	2012
High hydrostatic pressure activates transcription factors involved in Saccharomyces cerevisiae stress tolerance. Current pharmaceutical biotechnology\| PubMed ID: 23072392	2012
Noise and interlocking signaling pathways promote distinct transcription factor dynamics in response to different stresses. Molecular biology of the cell\| PubMed ID: 23615444	2013
Nucleotide degradation and ribose salvage in yeast. Molecular systems biology\| PubMed ID: 23670538	2013
The yeast environmental stress response regulates mutagenesis induced by proteotoxic stress. PLoS genetics\| PubMed ID: 23935537	2013
Genetic heterogeneity of amyotrophic lateral sclerosis: implications for clinical practice and research. Muscle & nerve\| PubMed ID: 24488689	2014
A dynamic interplay of nucleosome and Msn2 binding regulates kinetics of gene activation and repression following stress. Nucleic acids research\| PubMed ID: 24598258	2014