Ben Loos

Department of Physiology, Stellenbosch University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
Autophagy in heart disease: a strong hypothesis for an untouched metabolic reserve. Medical hypotheses\| PubMed ID: 21482032	2011
Use of a profluorophore for visualization of the rupture of capsules in self-healing coatings. Macromolecular rapid communications\| PubMed ID: 21590951	2010
Mitochondrial impairment observed in fibroblasts from South African Parkinson's disease patients with parkin mutations. Biochemical and biophysical research communications\| PubMed ID: 24721425	2014
Neurodegenerative disorders: dysregulation of a carefully maintained balance? Experimental gerontology\| PubMed ID: 25219768	2014
Mitochondrial catastrophe during doxorubicin-induced cardiotoxicity: a review of the protective role of melatonin. Journal of pineal research\| PubMed ID: 25230823	2014
Ascribing novel functions to the sarcomeric protein, myosin binding protein H (MyBPH) in cardiac sarcomere contraction. Experimental cell research\| PubMed ID: 25449695	2015
Evidence for a common biological pathway linking three Parkinson's disease-causing genes: parkin, PINK1 and DJ-1. The European journal of neuroscience\| PubMed ID: 25761903	2015
Melatonin: a protective role against doxorubicin-induced cardiotoxicity. Future oncology (London, England)\| PubMed ID: 26198826	2015
Bcl-2 confers survival in cisplatin treated cervical cancer cells: circumventing cisplatin dose-dependent toxicity and resistance. Journal of translational medicine\| PubMed ID: 26474854	2015
Filamin C: a novel component of the KCNE2 interactome during hypoxia. Cardiovascular journal of Africa\| PubMed ID: 26956495	2016
Curcumin Rescues a PINK1 Knock Down SH-SY5Y Cellular Model of Parkinson's Disease from Mitochondrial Dysfunction and Cell Death. Molecular neurobiology\| PubMed ID: 27003823	2017
Altered Mitochondrial Respiration and Other Features of Mitochondrial Function in Parkin-Mutant Fibroblasts from Parkinson's Disease Patients. Parkinson's disease\| PubMed ID: 27034887	2016
Autophagy--A free meal in sickness-associated anorexia. Autophagy\| PubMed ID: 27050464	2016
Caloric restriction and the precision-control of autophagy: A strategy for delaying neurodegenerative disease progression. Experimental gerontology\| PubMed ID: 27473756	2016
Virtual reality assisted microscopy data visualization and colocalization analysis. BMC bioinformatics\| PubMed ID: 28251867	2017
Autophagy and the invisible line between life and death. European journal of cell biology\| PubMed ID: 28340912	2016
Autophagic flux control in neurodegeneration: Progress and precision targeting-Where do we stand? Progress in neurobiology\| PubMed ID: 28385648	2017
Augmenting brain metabolism to increase macro- and chaperone-mediated autophagy for decreasing neuronal proteotoxicity and aging. Progress in neurobiology\| PubMed ID: 28502807	2017
Modulating autophagy in cancer therapy: Advancements and challenges for cancer cell death sensitization. Biochemical pharmacology\| PubMed ID: 29203368	2018
Nutrient excess and autophagic deficiency: explaining metabolic diseases in obesity. Metabolism: clinical and experimental\| PubMed ID: 29289514	2018
Doxorubicin resistance in breast cancer: A novel role for the human protein AHNAK. Biochemical pharmacology\| PubMed ID: 29309757	2018
Autophagy is essential for the maintenance of amino acids and ATP levels during acute amino acid starvation in MDAMB231 cells. Cell biochemistry and function\| PubMed ID: 29399832	2018
New Insights Into Autophagy Dysfunction Related to Amyloid Beta Toxicity and Neuropathology in Alzheimer's Disease. International review of cell and molecular biology\| PubMed ID: 29413893	2018
Melatonin improves cardiac and mitochondrial function during doxorubicin-induced cardiotoxicity: A possible role for peroxisome proliferator-activated receptor gamma coactivator 1-alpha and ... Toxicology and applied pharmacology\| PubMed ID: 29966675	2018
Coordinated autophagy modulation overcomes glioblastoma chemoresistance through disruption of mitochondrial bioenergetics. Scientific reports\| PubMed ID: 29985441	2018
The Precision Control of Autophagic Flux and Vesicle Dynamics-A Micropattern Approach. Cells\| PubMed ID: 30081508	2018
Improved region of interest selection and colocalization analysis in three-dimensional fluorescence microscopy samples using virtual reality. PloS one\| PubMed ID: 30157239	2018
Wild-type and mutant (G2019S) leucine-rich repeat kinase 2 (LRRK2) associate with subunits of the translocase of outer mitochondrial membrane (TOM) complex. Experimental cell research\| PubMed ID: 30597143	2019
The good, the bad and the autophagosome: exploring unanswered questions of autophagy-dependent cell death. Cell death and differentiation\| PubMed ID: 30659234	2019
The palladacycle complex AJ-5 induces apoptotic cell death while reducing autophagic flux in rhabdomyosarcoma cells. Cell death discovery\| PubMed ID: 30701092	2019
Ataxia-Telangiectasia Mutated is located in cardiac mitochondria and impacts oxidative phosphorylation. Scientific reports\| PubMed ID: 30886180	2019
Regression adjusted colocalisation colour mapping (RACC): A novel biological visual analysis method for qualitative colocalisation analysis of 3D fluorescence micrographs. PloS one\| PubMed ID: 31710634	2019
Supply and Demand Analysis of Autophagy. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 31893382	2020
Spatially and temporally defined lysosomal leakage facilitates mitotic chromosome segregation. Nature communications\| PubMed ID: 31932607	2020
Identification of a novel WAS mutation in a South African patient presenting with atypical Wiskott-Aldrich syndrome: a case report. BMC medical genetics\| PubMed ID: 32503528	2020
Mitochondrial event localiser (MEL) to quantitativelydescribe fission, fusion and depolarisation in the three-dimensional space. PloS one\| PubMed ID: 33378337	2020
Spermidine and Rapamycin Reveal Distinct Autophagy Flux Response and Cargo Receptor Clearance Profile. Cells\| PubMed ID: 33430464	2021
Can the interplay between autophagy and apoptosis be targeted as a novel therapy for Parkinson's disease? Neurobiology of aging\| PubMed ID: 33516928	2021
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy\| PubMed ID: 33634751	2021
A global view of standards for open image data formats and repositories. Nature methods\| PubMed ID: 33948027	2021
The palladacycle, BTC2, exhibits anti-breast cancer and breast cancer stem cell activity. Biochemical pharmacology\| PubMed ID: 33979647	2021
Interactions between developmental and adult acclimation have distinct consequences for heat tolerance and heat stress recovery. The Journal of experimental biology\| PubMed ID: 34308995	2021
Monitoring autophagy using super-resolution structured illumination and direct stochastic optical reconstruction microscopy. Methods in cell biology\| PubMed ID: 34311863	2021
Neurons die with heightened but functional macro- and chaperone mediated autophagy upon increased amyloid-ß induced toxicity with region-specific protection in prolonged intermittent fasting... Experimental cell research\| PubMed ID: 34624324	2021
Non-invasive monitoring of autophagy. Nature biomedical engineering\| PubMed ID: 36127452	2022
Measurement of Autophagy Activity Reveals Time-Dependent, Bacteria-Specific Turnover during Infection. Pathogens (Basel, Switzerland)\| PubMed ID: 36678372	2022
DRP1 mutations associated with EMPF1 encephalopathy alter mitochondrial membrane potential and metabolic programs. Journal of cell science\| PubMed ID: 36763487	2023
Rooibos tea-in the cross fire of ROS, mitochondrial dysfunction and loss of proteostasis-positioned for healthy aging. Biogerontology\| PubMed ID: 36781516	2023
The Highs and Lows of Memantine-An Autophagy and Mitophagy Inducing Agent That Protects Mitochondria. Cells\| PubMed ID: 37443760	2023
Propionic acid induces alterations in mitochondrial morphology and dynamics in SH-SY5Y cells. Scientific reports\| PubMed ID: 37582965	2023
Neutrophil extracellular trap formation and gene programs distinguish TST/IGRA sensitization outcomes among Mycobacterium tuberculosis exposed persons living with HIV. PLoS genetics\| PubMed ID: 37616312	2023
Exploring the connection between autophagy and heat-stress tolerance in . Proceedings. Biological sciences\| PubMed ID: 37700658	2023
Cogs in the autophagic machine-equipped to combat dementia-prone neurodegenerative diseases. Frontiers in molecular neuroscience\| PubMed ID: 37720551	2023
5-ALA localises to the autophagy compartment and increases its fluorescence upon autophagy enhancement through caloric restriction and spermidine treatment in human glioblastoma. Biochemistry and biophysics reports\| PubMed ID: 38288282	2024
International consensus guidelines for the definition, detection, and interpretation of autophagy-dependent ferroptosis. Autophagy\| PubMed ID: 38442890	2024
Next questions in autophagy. Nature cell biology\| PubMed ID: 38641661	2024
Antisecretory Factor 16 (AF16): A Promising Avenue for the Treatment of Traumatic Brain Injury-An In Vitro Model Approach. Journal of molecular neuroscience : MN\| PubMed ID: 39505761	2024
Correlative 3D imaging method for analysing lesion architecture in susceptible mice infected with Mycobacterium tuberculosis. Disease models & mechanisms\| PubMed ID: 40134379	2025
Favorably against the odds - autophagy control despite advanced amyloid- ß toxicity. Autophagy reports\| PubMed ID: 40396009	2022