Deborah L. French

Deborah L. French

Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia

Affiliated withChildren's Hospital of PhiladelphiaThe Children's Hospital of PhiladelphiaUniversity of Pennsylvania

Research Area

Biography

Deborah French is a Research Professor in the Department of Pathology and Laboratory Medicine, Perelman School of Medicine University of Pennsylvania. She is Director of the Human Pluripotent Stem Cell Core in the Center for Cellular and Molecular Therapeutics at The Children's Hospital of Philadelphia (CHOP).

Dr. French received her undergraduate degree from Purdue University and her graduate degree from Rush University. She completed her post-doctoral training in the laboratory of Dr. Matthew Scharff at the Albert Einstein College of Medicine.

In 2008, Dr. French established a core infrastructure at CHOP enabling investigators to work with pluripotent stem cells. She is a major collaborator of multi-investigator teams that are utilizing pluripotent stem cells for modeling human disease to study mechanism, development, and establish new therapeutic modalities.

JoVE Journal Publications

ArticleTotal : 2
Year
Generation of Human Induced Pluripotent Stem Cells from Peripheral Blood Using the STEMCCA Lentiviral Vector
Publication title

Cited by 80

2012
2019

Other Publications

Article
Year
Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells.

Cell stem cell| PubMed ID: 26607381

2016
2015
Monoclonal Antibodies by Somatic Cell Fusion.

ILAR journal / National Research Council, Institute of Laboratory Animal Resources| PubMed ID: 11528032

1995
2002
2003
2003
Integrin beta3 regions controlling binding of murine mAb 7E3: implications for the mechanism of integrin alphaIIbbeta3 activation.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 15277669

2004
2004
2006
2006
2010
2010
2011
2012
2012
Trisomy 21-associated defects in human primitive hematopoiesis revealed through induced pluripotent stem cells.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 23045704

2012
2013
2013
2013
2013
2013
2013
2014
2014
2014
Hematopoietic differentiation of pluripotent stem cells in culture.

Methods in molecular biology (Clifton, N.J.)| PubMed ID: 25062629

2014
2015
Pluripotent stem cells reveal erythroid-specific activities of the GATA1 N-terminus.

The Journal of clinical investigation| PubMed ID: 25621499

2015
A Doxycycline-Inducible System for Genetic Correction of iPSC Disease Models.

Methods in molecular biology (Clifton, N.J.)| PubMed ID: 25630922

2016
2015
2015
2015
2015
2016
2016
2016
2016
2017
2017
2018
GATA6 suppression enhances lung specification from human pluripotent stem cells.

The Journal of clinical investigation| PubMed ID: 29889101

2018
2018
Highly Efficient CRISPR-Cas9-Mediated Genome Editing in Human Pluripotent Stem Cells.

Current protocols in stem cell biology| PubMed ID: 30358158

2019
2019
2019