retrospective-case-analysis-transnasal-endoscopic-resection-orbital

Retrospective Case Analysis of Transnasal Endoscopic Resection of Orbital Apex Tumor

Endoscopic endonasal surgery has gained increasing recognition as an effective approach for the management of orbital tumors. In this study, we ...

Sun Yat-sen University

With rapid global urbanization, anthropogenic activities alter aquatic biota in urban rivers through inputs of dissolved organic carbon (DOC) and nutrients. Microorganisms-mediated global element cycles provide functions in maintaining microbial ecology stability. The DOC (bottom-up control) and microbial predation (top-down control) may synergistically drive the competition and evolution of aquatic microbial communities, as well as their resistance and resilience, for which experimental evidences remain scarce. In this study, laboratory sediment-water column experiments were employed to mimic the organic carbon-driven water blackening and odorization process in urban rivers and to elucidate the impact of DOC on microbial ecology stability. Results showed that low (25-75 mg/L) and high DOC (100-150 mg/L) changed the aquatic microbial community assemblies in different patterns: (1) the low DOC enriched K-selection microorganisms (e.g., C39, Tolumonas and CR08G) with low biomass and low resilience, as well as high resistance to perturbations in changing microbial community assemblies; (2) the high DOC was associated with r-selection microorganisms (e.g., PSB-M-3 and Clostridium) with high biomass and improved resilience, together with low resistance detrimental to microbial ecology stability. Overall, this study provided new insight into the impact of DOC on aquatic microbial community stability, which may help guide sustainable urban river management.

Organic carbon and eukaryotic predation synergistically change resistance and resilience of aquatic microbial communities.

To investigate the clinical efficacy and prognostic factors of transnasal endoscopic optic decompression in the treatment of traumatic optic neuropathy (TON).

Diagnosis and treatment of transnasal endoscopic optic canal decompression for traumatic optic neuropathy.

Genetic testing for pathogenic DNA damage repair gene (pDDRg) mutations has clinical benefits for prostate cancer (PCa) patients, but its real-world application faces challenges due to its high associated costs. We sought to develop a magnetic resonance imaging (MRI)-based radiomics model capable of assessing the likelihood of PCa patients harboring pDDRg mutations. We then rigorously validated its predictive value in two external validation cohorts.

Predicting pathogenic DNA damage repair gene mutations in prostate cancer patients: a multi-center magnetic resonance imaging radiomics study.

This study aimed to develop a hybrid deep learning model for classifying multiple fundus diseases using ultra-widefield (UWF) images, thereby improving diagnostic efficiency and accuracy while providing an auxiliary tool for clinical decision-making.

Article	Year
Organic carbon and eukaryotic predation synergistically change resistance and resilience of aquatic microbial communities. The Science of the total environment\| PubMed ID: 35331758	2022
Diagnosis and treatment of transnasal endoscopic optic canal decompression for traumatic optic neuropathy. Frontiers in neuroscience\| PubMed ID: 37260841	2023
Predicting pathogenic DNA damage repair gene mutations in prostate cancer patients: a multi-center magnetic resonance imaging radiomics study. Quantitative imaging in medicine and surgery\| PubMed ID: 40727372	2025
Deep learning-based classification of multiple fundus diseases using ultra-widefield images. Frontiers in cell and developmental biology\| PubMed ID: 40746855	2025

Xiang Tu

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