the-impact-cyp3a4-comt-v158m-oprm-a118g-gene-polymorphisms-on

The Impact of CYP3A4, COMT V158M, and OPRM A118G Gene Polymorphisms on the Effectiveness of Sufentanil in Labor Analgesia

Genetic polymorphisms in CYP3A4, COMT V158M, and OPRM A118G may influence analgesic response, hemodynamic regulation, and postpartum recovery, while ...

Xiamen University

To investigate the relationship between intrapartum maternal fever and the duration and dosage of patient-controlled epidural analgesia (PCEA).

Time- and dose-dependent correlations between patient-controlled epidural analgesia and intrapartum maternal fever.

This study aims to analyze the influence of different dexmedetomidine doses on cognitive function. It works on early periods of patients undergoing laparoscopic extensive total hysterectomy.

The Influence of Different Dexmedetomidine Doses on Cognitive Function at Early Period of Patients Undergoing Laparoscopic Extensive Total Hysterectomy.

The aim of the study was to estimate the impact of epidural analgesia (EA) during delivery on maternal and infant outcomes.

Effects of Using Epidural Analgesia during Delivery on Maternal and Infant Outcomes.

We aimed to explore the association between epidural-related maternal fever (ERMF) and prognosis of parturients. 159 parturients who underwent vaginal delivery under labor epidural analgesia (LEA) received noninvasive continuous core body temperature monitoring. 122 of them completed the 42-day postpartum follow-up. Parturients with body temperature ≥38°C during labor were categorized as the Fever group, while the others were categorized as the No-Fever group. Compared to No-Fever group, Fever group had a greater proportion of primiparas, greater gestational age of parturients, and longer third stage of labor. The cesarean section and forceps delivery rates, and the amount of intrapartum hemorrhage in Fever group were significantly higher. There were no significant between-group differences with respect to puerperal infection, and amniotic fluid turbidity degree, neither significant between-group difference at 42-days postpartum. We found that ERMF was associated with some short-term outcomes. However, it showed no relation with long-term prognosis of the parturients at 42-days postpartum.

Association between epidural-related maternal fever and short-and long-term prognosis of parturients: A prospective observational study.

Epidural-related maternal fever increases the incidence of Category II fetal tracings. To compare the effectiveness of low-flow oxygen inhalation and cooling treatment for parturients with Category II fetal tracings caused by epidural-related maternal fever.

Cooling treatment on the reduction of category II fetal tracings.

Erythrocytes from patients with thalassemia might be susceptible to hemolysis during recycling and washing. Therefore, autologous erythrocyte transfusion using erythrocytes from parturient women with thalassemia has been suggested as a relative contraindication. Only a limited number of successful cases have been documented to date, and few clinical studies with large sample sizes are available as evidence to support this practice. This study aimed to assess the intraoperative safety and the degree of postoperative anemia correction in women with thalassemia receiving erythrocyte transfusions during cesarean section.

Article	Year
Time- and dose-dependent correlations between patient-controlled epidural analgesia and intrapartum maternal fever. BMC anesthesiology\| PubMed ID: 33514322	2021
The Influence of Different Dexmedetomidine Doses on Cognitive Function at Early Period of Patients Undergoing Laparoscopic Extensive Total Hysterectomy. Journal of healthcare engineering\| PubMed ID: 34621501	2021
Effects of Using Epidural Analgesia during Delivery on Maternal and Infant Outcomes. Gynecologic and obstetric investigation\| PubMed ID: 35294944	2022
Association between epidural-related maternal fever and short-and long-term prognosis of parturients: A prospective observational study. Frontiers in surgery\| PubMed ID: 36704517	2022
Cooling treatment on the reduction of category II fetal tracings. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians\| PubMed ID: 38199819	2024
Twenty-eight cases of thalassemia: A retrospective study of autologous and allogeneic erythrocyte transfusions during cesarean section. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics\| PubMed ID: 40817720	2025

Junxiang Jia

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