the-impact-cyp3a4-comt-v158m-oprm-a118g-gene-polymorphisms-on

The Impact of CYP3A4, COMT V158M, and OPRM A118G Gene Polymorphisms on the Effectiveness of Sufentanil in Labor Analgesia

Genetic polymorphisms in CYP3A4, COMT V158M, and OPRM A118G may influence analgesic response, hemodynamic regulation, and postpartum recovery, while ...

Xiamen University

To explore whether resveratrol can reduce intestinal damage in hemorrhagic shock rats and the underlying mechanism.

[Resveratrol improves intestinal injury in hemorrhagic shock rats by protection of mitochondria and reduction of oxidative stress].

The aim of this study was to evaluate the effect of isoflurane + NO inhalation and propofol + fentanyl anesthesia on myocardial function as assessed by cardiac troponin T (cTnT). A total of 60 patients were randomized into two groups: isoflurane + NO inhalation (n=30) and propofol + fentanyl anesthesia (n=30). The findings demonstrated that there was no significant difference between the two experimental groups in terms of cTnT levels, demographic properties or hemodynamic parameters. Isoflurane + NO inhalation and propofol + fentanyl anesthesia, respectively, were also investigated in a rat model of myocardial infarction. Myocardial cell damage, inflammation and oxidative stress levels, caspase-3/9 activities and cyclooxygenase-2 protein expression were markedly decreased, although there was no statistical significance difference between the two experimental groups. Notably, inducible nitric oxide synthase protein expression in the isoflurane + NO inhalation group was significantly higher than that of the propofol + fentanyl anesthesia group (P<0.01). In conclusion, isoflurane + NO inhalation and propofol + fentanyl anesthesia are not associated with risks for myocardial function.

Effect of isoflurane + NO inhalation and propofol + fentanyl anesthesia on myocardial function as assessed by cardiac troponin, caspase-3, cyclooxygenase-2 and inducible nitric oxide synthase expression.

To analyze the outcome of 147 cases of type B aortic dissection with thoracic endovascular aortic repair (TEVAR).

Article	Year
[Resveratrol improves intestinal injury in hemorrhagic shock rats by protection of mitochondria and reduction of oxidative stress]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences\| PubMed ID: 25544172	2014
Effect of isoflurane + NO inhalation and propofol + fentanyl anesthesia on myocardial function as assessed by cardiac troponin, caspase-3, cyclooxygenase-2 and inducible nitric oxide synthas... Experimental and therapeutic medicine\| PubMed ID: 29067116	2017
Complications after treatment of type B aortic dissection with TEVAR stent-graft deployment in zone 2. BMC cardiovascular disorders\| PubMed ID: 39934656	2025

Zhuanghui Zhu

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