Brian Seed

Center for Computational and Integrative Biology, Massachusetts General Hospital

Affiliated withMassachusetts General Hospital

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2012

Other Publications

Article	Year
Identification of a novel Ras-regulated proapoptotic pathway. Current biology : CB\| PubMed ID: 11864565	2002
Site-specific gene targeting in mouse embryonic stem cells with intact bacterial artificial chromosomes. Nature biotechnology\| PubMed ID: 12627171	2003
Selection of oligonucleotide probes for protein coding sequences. Bioinformatics (Oxford, England)\| PubMed ID: 12724288	2003
Dynamic imaging of collagen and its modulation in tumors in vivo using second-harmonic generation. Nature medicine\| PubMed ID: 12754503	2003
The cell adhesion protein P-selectin glycoprotein ligand-1 is a substrate for the aspartyl protease BACE1. The Journal of biological chemistry\| PubMed ID: 14507929	2003
A PCR primer bank for quantitative gene expression analysis. Nucleic acids research\| PubMed ID: 14654707	2003
Epstein-Barr virus latent infection membrane protein 1 TRAF-binding site induces NIK/IKK alpha-dependent noncanonical NF-kappaB activation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14691250	2004
The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death. The Journal of biological chemistry\| PubMed ID: 15075335	2004
Discs large (Dlg1) complexes in lymphocyte activation. The Journal of cell biology\| PubMed ID: 15263016	2004
The knockout mouse project. Nature genetics\| PubMed ID: 15340423	2004
Differential transplantability of tumor-associated stromal cells. Cancer research\| PubMed ID: 15342367	2004
Identification of eosinophil lineage-committed progenitors in the murine bone marrow. The Journal of experimental medicine\| PubMed ID: 15955840	2005
PDZ domains and the politics of polarity in lymphocytes. Immunity\| PubMed ID: 15963778	2005
Large-scale screens for cDNAs with in vivo activity. Novartis Foundation symposium\| PubMed ID: 15999809	2005
B cell maturation antigen, the receptor for a proliferation-inducing ligand and B cell-activating factor of the TNF family, induces antigen presentation in B cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16116167	2005
Expression cloning screen for modifiers of amyloid precursor protein shedding. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience\| PubMed ID: 16446073	2006
CARMA1 is critical for the development of allergic airway inflammation in a murine model of asthma. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16751370	2006
A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies. Nature biotechnology\| PubMed ID: 16823376	2006
Direct stimulation of T lymphocytes by immunosomes: virus-like particles decorated with T cell receptor/CD3 ligands plus costimulatory molecules. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16924110	2006
ABCA3 inactivation in mice causes respiratory failure, loss of pulmonary surfactant, and depletion of lung phosphatidylglycerol. Journal of lipid research\| PubMed ID: 17142808	2007
General strategy for decoration of enveloped viruses with functionally active lipid-modified cytokines. Journal of virology\| PubMed ID: 17537846	2007
Molecular and functional analysis of the antigen receptor of Art v 1-specific helper T lymphocytes. The Journal of allergy and clinical immunology\| PubMed ID: 18037161	2008
A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein. The Journal of biological chemistry\| PubMed ID: 18353773	2008
A pathway sensor for genome-wide screens of intracellular proteolytic cleavage. Genome biology\| PubMed ID: 18387192	2008
Spinophilin and the immune synapse. The Journal of cell biology\| PubMed ID: 18411314	2008
Quantitation of autophagy by luciferase release assay. Autophagy\| PubMed ID: 18641457	2008
A comprehensive collection of experimentally validated primers for Polymerase Chain Reaction quantitation of murine transcript abundance. BMC genomics\| PubMed ID: 19108745	2008
Lack of lymphatic vessel phenotype in LYVE-1/CD44 double knockout mice. Journal of cellular physiology\| PubMed ID: 19170073	2009
Modulation of allergen-specific T-lymphocyte function by virus-like particles decorated with HLA class II molecules. The Journal of allergy and clinical immunology\| PubMed ID: 19500826	2009
O-Spiro C-aryl glucosides as novel sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors. Bioorganic & medicinal chemistry letters\| PubMed ID: 19700318	2009
Exploration of O-spiroketal C-arylglucosides as novel and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors. Bioorganic & medicinal chemistry letters\| PubMed ID: 19896374	2009
PrimerBank: a resource of human and mouse PCR primer pairs for gene expression detection and quantification. Nucleic acids research\| PubMed ID: 19906719	2010
Fluorosomes: a convenient new reagent to detect and block multivalent and complex receptor-ligand interactions. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 20056716	2010
Host-encoded reporters for the detection and purification of multiple enveloped viruses. Journal of virological methods\| PubMed ID: 20399809	2010
Conformationally constrained spiro C-arylglucosides as potent and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors. ChemMedChem\| PubMed ID: 20414917	2010
Activating WASP mutations associated with X-linked neutropenia result in enhanced actin polymerization, altered cytoskeletal responses, and genomic instability in lymphocytes. The Journal of experimental medicine\| PubMed ID: 20513746	2010
Mice lacking Dok-1, Dok-2, and Dok-3 succumb to aggressive histiocytic sarcoma. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 20548287	2010
ortho-Substituted C-aryl glucosides as highly potent and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors. Bioorganic & medicinal chemistry\| PubMed ID: 20576578	2010
The transcription factor MafB antagonizes antiviral responses by blocking recruitment of coactivators to the transcription factor IRF3. Nature immunology\| PubMed ID: 20581830	2010
EGT1442, a potent and selective SGLT2 inhibitor, attenuates blood glucose and HbA(1c) levels in db/db mice and prolongs the survival of stroke-prone rats. Pharmacological research : the official journal of the Italian Pharmacological Society\| PubMed ID: 21215314	2011
C-aryl glucosides substituted at the 4'-position as potent and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes. Bioorganic & medicinal chemistry letters\| PubMed ID: 21737266	2011
Phosphoprotein associated with glycosphingolipid-enriched microdomains differentially modulates SRC kinase activity in brain maturation. PloS one\| PubMed ID: 21915273	2011
PrimerBank: a PCR primer database for quantitative gene expression analysis, 2012 update. Nucleic acids research\| PubMed ID: 22086960	2012
STAT6 phosphorylation inhibitors block eotaxin-3 secretion in bronchial epithelial cells. Bioorganic & medicinal chemistry\| PubMed ID: 22217933	2012
Enhanced tim3 activity improves survival after influenza infection. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 22875804	2012