Nanping Wang

Advanced Institute for Medical Sciences, Dalian Medical University

Affiliated withDalian Medical University East China Normal University Health Science Center

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title	2025
Publication title	2026

Other Publications

Article	Year
Pro-inflammatory Macrophages suppress PPARγ activity in Adipocytes via S-nitrosylation. Free radical biology & medicine\| PubMed ID: 26475041	2015
Plasticizer DBP Activates NLRP3 Inflammasome through the P2X7 Receptor in HepG2 and L02 Cells. Journal of biochemical and molecular toxicology\| PubMed ID: 26586371	2016
Homocysteine upregulates hepcidin expression through BMP6/SMAD signaling pathway in hepatocytes. Biochemical and biophysical research communications\| PubMed ID: 26855134	2016
PPARgene: A Database of Experimentally Verified and Computationally Predicted PPAR Target Genes. PPAR research\| PubMed ID: 27148361	2016
GHSR deficiency suppresses neointimal formation in injured mouse arteries. Biochemical and biophysical research communications\| PubMed ID: 27404127	2016
Prostaglandin E2 receptor EP3 regulates both adipogenesis and lipolysis in mouse white adipose tissue. Journal of molecular cell biology\| PubMed ID: 27436752	2016
Adipocyte-specific loss of PPAR attenuates cardiac hypertrophy. JCI insight\| PubMed ID: 27734035	2016
Retinoid acid receptor-related orphan receptor alpha (RORα) regulates macrophage M2 polarization via activation of AMPKα. Molecular immunology\| PubMed ID: 27788394	2016
MTUS1 silencing promotes E-selectin production through p38 MAPK-dependent CREB ubiquitination in endothelial cells. Journal of molecular and cellular cardiology\| PubMed ID: 27789289	2016
PPARδ Is Required for Exercise to Attenuate Endoplasmic Reticulum Stress and Endothelial Dysfunction in Diabetic Mice. Diabetes\| PubMed ID: 27856609	2017
Peroxisome proliferator-activated receptor α ligands and modulators from dietary compounds: Types, screening methods and functions. Journal of diabetes\| PubMed ID: 27863018	2017
Systematic Characterization and Prediction of Human Hypertension Genes. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 27895194	2017
Integrin-YAP/TAZ-JNK cascade mediates atheroprotective effect of unidirectional shear flow. Nature\| PubMed ID: 27926730	2016
Liver X receptor β increases aquaporin 2 protein level via a posttranscriptional mechanism in renal collecting ducts. American journal of physiology. Renal physiology\| PubMed ID: 28052875	2017
Oleanolic acid ameliorates high glucose-induced endothelial dysfunction via PPARδ activation. Scientific reports\| PubMed ID: 28067284	2017
Tripartite motif-containing 28 bridges endothelial inflammation and angiogenic activity by retaining expression of TNFR-1 and -2 and VEGFR2 in endothelial cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 28159803	2017
Statins Attenuate Activation of the NLRP3 Inflammasome by Oxidized LDL or TNF in Vascular Endothelial Cells through a PXR-Dependent Mechanism. Molecular pharmacology\| PubMed ID: 28546421	2017
Inhibition of 5-Hydroxytryptamine Receptor 2B Reduced Vascular Restenosis and Mitigated the β-Arrestin2-Mammalian Target of Rapamycin/p70S6K Pathway. Journal of the American Heart Association\| PubMed ID: 29382665	2018
Microtubule associated tumor suppressor 1 interacts with mitofusins to regulate mitochondrial morphology in endothelial cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 29558204	2018
Inhibition of mTOR ameliorates bleomycin-induced pulmonary fibrosis by regulating epithelial-mesenchymal transition. Biochemical and biophysical research communications\| PubMed ID: 29704504	2018
Farnesoid X receptor is essential for the survival of renal medullary collecting duct cells under hypertonic stress. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 29739889	2018
Cornulin Is Induced in Psoriasis Lesions and Promotes Keratinocyte Proliferation via Phosphoinositide 3-Kinase/Akt Pathways. The Journal of investigative dermatology\| PubMed ID: 30009832	2019
Nuciferine ameliorates hepatic steatosis in high-fat diet/streptozocin-induced diabetic mice through a PPARα/PPARγ coactivator-1α pathway. British journal of pharmacology\| PubMed ID: 30129056	2018
Xenobiotic pregnane X receptor promotes neointimal formation in balloon-injured rat carotid arteries. Journal of cellular physiology\| PubMed ID: 30132884	2019
Stachydrine protects eNOS uncoupling and ameliorates endothelial dysfunction induced by homocysteine. Molecular medicine (Cambridge, Mass.)\| PubMed ID: 30134790	2018
Peroxisome proliferator-activated receptor γ (PPARγ) induces the gene expression of integrin αβ to promote macrophage M2 polarization. The Journal of biological chemistry\| PubMed ID: 30181212	2018
Nuciferine Inhibits Proinflammatory Cytokines via the PPARs in LPS-Induced RAW264.7 Cells. Molecules (Basel, Switzerland)\| PubMed ID: 30360404	2018
Resveratrol ameliorates endothelial dysfunction in diabetic and obese mice through sirtuin 1 and peroxisome proliferator-activated receptor δ. Pharmacological research\| PubMed ID: 30503839	2019
Sonic hedgehog signaling instigates high-fat diet-induced insulin resistance by targeting PPARγ stability. The Journal of biological chemistry\| PubMed ID: 30573683	2019
S-nitrosation impairs KLF4 activity and instigates endothelial dysfunction in pulmonary arterial hypertension. Redox biology\| PubMed ID: 30660098	2019
VSMC-specific EP4 deletion exacerbates angiotensin II-induced aortic dissection by increasing vascular inflammation and blood pressure. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 30948641	2019
PPARδ agonist prevents endothelial dysfunction via induction of dihydrofolate reductase gene and activation of tetrahydrobiopterin salvage pathway. British journal of pharmacology\| PubMed ID: 31144304	2019
NR6A1 regulates lipid metabolism through mammalian target of rapamycin complex 1 in HepG2 cells. Cell communication and signaling : CCS\| PubMed ID: 31315616	2019
PPARγ induces NEDD4 gene expression to promote autophagy and insulin action. The FEBS journal\| PubMed ID: 31423749	2020
Procyanidin B2 Activates PPARγ to Induce M2 Polarization in Mouse Macrophages. Frontiers in immunology\| PubMed ID: 31440258	2019
APC/Cdh1 targets PECAM-1 for ubiquitination and degradation in endothelial cells. Journal of cellular physiology\| PubMed ID: 31489637	2020
GHSR deficiency exacerbates cardiac fibrosis: role in macrophage inflammasome activation and myofibroblast differentiation. Cardiovascular research\| PubMed ID: 31790138	2020
TRIM28 and TRIM27 are required for expressions of PDGFRβ and contractile phenotypic genes by vascular smooth muscle cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 32162409	2020
Endothelial cell prostaglandin E2 receptor EP4 is essential for blood pressure homeostasis. JCI insight\| PubMed ID: 32641583	2020
TRIM28 regulates sprouting angiogenesis through VEGFR-DLL4-Notch signaling circuit. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 32918765	2020
Procyanidin B2 mitigates endothelial endoplasmic reticulum stress through a PPARδ-Dependent mechanism. Redox biology\| PubMed ID: 32961442	2020
Xenobiotic Receptor CAR Is Highly Induced in Psoriasis and Promotes Keratinocyte Proliferation. The Journal of investigative dermatology\| PubMed ID: 34097921	2021
TRIM28 regulates SARS-CoV-2 cell entry by targeting ACE2. Cellular signalling\| PubMed ID: 34146659	2021
Sodium-Glucose Cotransporter-2 Inhibitors in Vascular Biology: Cellular and Molecular Mechanisms. Cardiovascular drugs and therapy\| PubMed ID: 34273091	2021
Procyanidin B2 Attenuates Nicotine-Induced Hepatocyte Pyroptosis through a PPARγ-Dependent Mechanism. Nutrients\| PubMed ID: 35565726	2022
CCN1/Integrin αβ Instigates Free Fatty Acid-Induced Hepatocyte Lipid Accumulation and Pyroptosis through NLRP3 Inflammasome Activation. Nutrients\| PubMed ID: 36145246	2022
Free fatty acids stabilize integrin βvia S-nitrosylation to promote monocyte-endothelial adhesion. The Journal of biological chemistry\| PubMed ID: 36470423	2023
A critical role of the endothelial S-phase kinase-associated protein 2/phosphatase and tensin homologue axis in angiogenesis and psoriasis. The British journal of dermatology\| PubMed ID: 37850885	2024
S-nitrosylation attenuates pregnane X receptor hyperactivity and acetaminophen-induced liver injury. JCI insight\| PubMed ID: 38032737	2024
Deficiency of 5-HT receptors alleviates atherosclerosis by regulating macrophage phenotype through inhibiting interferon signalling. British journal of pharmacology\| PubMed ID: 39232850	2024