Roland E. Akhigbe

Department of Physiology, Ladoke Akintola University of Technology

Affiliated withLadoke Akintola University of Technology Oasis of Grace Hospital

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
Testicular toxicity and sperm quality following cadmium exposure in rats: Ameliorative potentials of Allium cepa. Journal of human reproductive sciences\| PubMed ID: 22870013	2012
Antifertility activity of Cryptolepis sanguinolenta leaf ethanolic extract in male rats. Journal of human reproductive sciences\| PubMed ID: 22870014	2012
Scientific journals: Indexation and impact factor. Lung India : official organ of Indian Chest Society\| PubMed ID: 22919179	2012
The role of Allium cepa on aluminum-induced reproductive dysfunction in experimental male rat models. Journal of human reproductive sciences\| PubMed ID: 23162360	2012
Exposure to petroleum hydrocarbon: implications in lung lipid peroxidation and antioxidant defense system in rat. Toxicology international\| PubMed ID: 23293471	2012
Oxidative status in rat kidney exposed to petroleum hydrocarbons. Journal of natural science, biology, and medicine\| PubMed ID: 23633852	2013
Prevalence and pattern of utilization of voluntary counseling and testing services and HIV infection in Ogbomoso, southwestern Nigeria. Journal of natural science, biology, and medicine\| PubMed ID: 23633855	2013
Antispermatogenic Mechanism of Trona is Associated with Lipid Peroxidation but Not Testosterone Suppression. Journal of human reproductive sciences\| PubMed ID: 28904502	2017
Staging of the estrous cycle and induction of estrus in experimental rodents: an update. Fertility research and practice\| PubMed ID: 32190339	2020
Codeine-induced sperm DNA damage is mediated predominantly by oxidative stress rather than apoptosis. Redox report : communications in free radical research\| PubMed ID: 32290793	2020
The physiology of male reproduction: Impact of drugs and their abuse on male fertility. Andrologia\| PubMed ID: 32542870	2020
seed oil partially abrogates 2,3-dichlorovinyl dimethyl phosphate (Dichlorvos)-induced cardiac injury in rats: evidence for the role of oxidative stress. Journal of basic and clinical physiology and pharmacology\| PubMed ID: 33141105	2020
Rohypnol-induced sexual dysfunction is via suppression of hypothalamic-pituitary-testicular axis: An experimental study in rats. Andrologia\| PubMed ID: 33378084	2021
HAART and anti-Koch's impair sexual competence, sperm quality and offspring quality when used singly and in combination in male Wistar rats. Andrologia\| PubMed ID: 33400320	2021
Irisin, Energy Homeostasis and Male Reproduction. Frontiers in physiology\| PubMed ID: 34621189	2021
Oxidative Stress and Cardiometabolic Disorders. BioMed research international\| PubMed ID: 34790826	2021
Restoration of Hepatic and Intestinal Integrity by Is Dependent on Bax/Caspase 3 Modulation in Intestinal Ischemia-/Reperfusion-Induced Injury. Molecules (Basel, Switzerland)\| PubMed ID: 36014309	2022
Influence of ejaculatory abstinence period on semen quality of 5165 normozoospermic and oligozoospermic Nigerian men: A retrospective study. Health science reports\| PubMed ID: 36032514	2022
Predictors of Sex-Induced Crisis, Sexual Function and Marital Satisfaction in Women With Sickle Cell Disease. The journal of sexual medicine\| PubMed ID: 36088276	2022
L-Arginine reverses maternal and pre-pubertal codeine exposure-induced sexual dysfunction via upregulation of androgen receptor gene and NO/cGMP signaling. PloS one\| PubMed ID: 36099318	2022
Viral Infections and Male Infertility: A Comprehensive Review of the Role of Oxidative Stress. Frontiers in reproductive health\| PubMed ID: 36303638	2022
Progress in research on the reproductive function in the sand rat (Psammomys obesus): A review. General and comparative endocrinology\| PubMed ID: 36368440	2023
Zinc improves sexual performance and erectile function by preventing penile oxidative injury and upregulating circulating testosterone in lead-exposed rats. Redox report : communications in free radical research\| PubMed ID: 37345699	2023
Psychoactive drugs and male fertility: impacts and mechanisms. Reproductive biology and endocrinology : RB&E\| PubMed ID: 37507788	2023
L-Arginine abrogates maternal and pre-pubertal codeine exposure-induced impaired spermatogenesis and sperm quality by modulating the levels of mRNA encoding spermatogenic genes. Frontiers in endocrinology\| PubMed ID: 37529606	2023
Impact of organophosphate pesticides exposure on human semen parameters and testosterone: a systematic review and meta-analysis. Frontiers in endocrinology\| PubMed ID: 37964951	2023
Glutamine Alleviates I/R-Induced Intestinal Injury and Dysmotility Via the Downregulation of Xanthine Oxidase/Uric Acid Signaling and Lactate Generation in Wistar Rats. The Journal of surgical research\| PubMed ID: 38070257	2024
Histopathological evaluation of infertility: Lessons from laboratory rodents. Histology and histopathology\| PubMed ID: 38088133	2024
Impact of stress on male fertility: role of gonadotropin inhibitory hormone. Frontiers in endocrinology\| PubMed ID: 38260147	2023
Gut microbiota-gonadal axis: the impact of gut microbiota on reproductive functions. Frontiers in immunology\| PubMed ID: 38482009	2024
Glutamine-mediated Modulation of XO/uric acid/NF-kB Signaling Pathway Ameliorates Intestinal I/R-induced Bacterial Translocation and Cardiorenal Inflammatory Injury. Cell biochemistry and biophysics\| PubMed ID: 38530591	2024
-based feed supplement protects against renal ischaemia/reperfusion injury via downregulation of Bax/caspase 3 signaling. Frontiers in nutrition\| PubMed ID: 38716072	2024
Sodium acetate prevents testicular damage in Wistar rats subjected to testicular ischaemia/reperfusion injury. Experimental and molecular pathology\| PubMed ID: 38749364	2024
Molecular mechanisms underpinning the protection against antiretroviral drug-induced sperm-endocrine aberrations and testicular toxicity: A review. Reproductive toxicology (Elmsford, N.Y.)\| PubMed ID: 38825169	2024
Does pyrethroid exposure lower human semen quality? a systematic review and meta-analysis. Frontiers in toxicology\| PubMed ID: 38919453	2024
Toxic impacts of arsenic bioaccumulation on urinary arsenic metabolites and semen quality: A systematic and meta-analysis. Ecotoxicology and environmental safety\| PubMed ID: 38941661	2024
Testicular toxicity in cisplatin-treated Wistar rats is mitigated by Daflon and associated with modulation of Nrf2/HO-1 and TLR4/NF-kB signaling. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)\| PubMed ID: 38943836	2024
Comparison of the effectiveness of levonorgestrel intrauterine system and dienogest in the management of adenomyosis: A systematic review and meta-analysis. European journal of obstetrics, gynecology, and reproductive biology\| PubMed ID: 39032312	2024
Omega-3 fatty acids abrogates oxido-inflammatory and mitochondrial dysfunction-associated apoptotic responses in testis of tamoxifen-treated rats. Frontiers in nutrition\| PubMed ID: 39149552	2024
Impact of arsenic on male and female reproductive function: a review of the pathophysiology and potential therapeutic strategies. Naunyn-Schmiedeberg's archives of pharmacology\| PubMed ID: 39287676	2025
Acetate attenuates lead-induced dysregulation of testicular steroidogenesis and spermatogenesis by targeting oxidative stress, inflammatory cytokines, and apoptosis. Toxicological research\| PubMed ID: 39345745	2024
Understanding the intricate impacts and mechanism of actions of adaptogens on reproductive function. Cell biochemistry and biophysics\| PubMed ID: 39369159	2025
A systematic review and meta-analysis of the impact of triclosan exposure on human semen quality. Frontiers in toxicology\| PubMed ID: 39483697	2024
Estrogen replacement therapy reverses spatial memory loss and pyramidal cell neurodegeneration in the prefrontal cortex of lead-exposed ovariectomized Wistar rats. Current research in toxicology\| PubMed ID: 39583742	2024
Mechanisms of ferroptotic and non-ferroptotic organ toxicity of chemotherapy: protective and therapeutic effects of ginger, 6-gingerol and zingerone in preclinical studies. Naunyn-Schmiedeberg's archives of pharmacology\| PubMed ID: 39636404	2025
Editorial: Environmental threats to human reproduction. Frontiers in endocrinology\| PubMed ID: 39687077	2024
Unraveling the complexity of the impact of physical exercise on male reproductive functions: a review of both sides of a coin. Frontiers in physiology\| PubMed ID: 39726860	2024
Does coenzyme Q10 improve semen quality and circulating testosterone level? a systematic review and meta-analysis of randomized controlled trials. Frontiers in pharmacology\| PubMed ID: 39830337	2024
Re: Letter to the editor: Comparison of the effectiveness of levonorgestrel intrauterine system and dienogest in the management of adenomyosis: A systematic review and meta-analysis. European journal of obstetrics, gynecology, and reproductive biology\| PubMed ID: 39952810	2025
Silymarin attenuates post-weaning bisphenol A-induced renal injury by suppressing ferroptosis and amyloidosis through Kim-1/Nrf2/HO-1 signaling modulation in male Wistar rats. Biochemical and biophysical research communications\| PubMed ID: 40120348	2025
Ureaplasma urealyticum upregulates seminal fluid leukocytes and lowers human semen quality: a systematic review and meta-analysis. Basic and clinical andrology\| PubMed ID: 40247169	2025
Corrigendum to "Comparison of effectiveness of the levonorgestrel intrauterine system and dienogest in the management of adenomyosis: A systematic review and meta-analysis" [Eur. J. Obstetr.... European journal of obstetrics, gynecology, and reproductive biology\| PubMed ID: 40347859	2025
Micronized Purified Flavonoid Fraction (Diosmin/Hesperidin) Ameliorates Cardiac Structural and Functional Integrity in Cisplatin-treated Male Wistar Rats by Modulating NLRP3/Caspase-1/-3 Sig... Cell biochemistry and biophysics\| PubMed ID: 40358918	2025
Omega-3 fatty acids improves tamoxifen-induced sexual dysfunction in male Wistar rats by modulating NO/cGMP signaling and monoamine neurotransmitters activities. Psychopharmacology\| PubMed ID: 40528104	2025
Editorial: Oxidative stress and male fertility. Frontiers in reproductive health\| PubMed ID: 40792308	2025
Neurotoxic effects of acyclovir: impacts on oxidative stress, inflammation, and neurotransmitter dynamics in male Wistar rats. Metabolic brain disease\| PubMed ID: 40892179	2025