Xiaofei Shen

TCM Prevention and Treatment of Metabolic and Chronic Diseases Key Laboratory of Sichuan Province, Chengdu University of Traditional Chinese Medicine

Affiliated withChengdu University of Traditional Chinese Medicine

Research Area

Medicine

Biography

Xiaofei Shen has not added Biography.
If you are Xiaofei Shen and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2026

Other Publications

Article	Year
Analgesic effect and mechanism of the three TCM-herbal drug-combination Tou Feng Yu pill on treatment of migraine. Phytomedicine : international journal of phytotherapy and phytopharmacology\| PubMed ID: 21315572	2011
Emodin potentiates the antiproliferative effect of interferon α/β by activation of JAK/STAT pathway signaling through inhibition of the 26S proteasome. Oncotarget\| PubMed ID: 26683360	2016
Dietary apigenin potentiates the inhibitory effect of interferon-α on cancer cell viability through inhibition of 26S proteasome-mediated interferon receptor degradation. Food & nutrition research\| PubMed ID: 27356910	2016
The anti-arthritic activity of total glycosides from Pterocephalus hookeri, a traditional Tibetan herbal medicine. Pharmaceutical biology\| PubMed ID: 27937009	2017
Astragalus polysaccharides exerts anti-infective activity by inducing human cathelicidin antimicrobial peptide LL-37 in respiratory epithelial cells. Phytotherapy research : PTR\| PubMed ID: 29672953	2018
A new xanthatin analogue 1β-hydroxyl-5α-chloro-8-epi-xanthatin induces apoptosis through ROS-mediated ERK/p38 MAPK activation and JAK2/STAT3 inhibition in human hepatocellular carcinoma. Biochimie\| PubMed ID: 29960031	2018
The total alkaloids from Franch improve cognitive deficits in type 2 diabetic rats. Drug design, development and therapy\| PubMed ID: 30214157	2018
A new abietane diterpenoid glycoside from var. . Natural product research\| PubMed ID: 30422013	2019
Pseudolaric acid B exhibits anti-cancer activity on human hepatocellular carcinoma through inhibition of multiple carcinogenic signaling pathways. Phytomedicine : international journal of phytotherapy and phytopharmacology\| PubMed ID: 31004883	2019
Ajudecumin A from Ajuga ovalifolia var. calantha exhibits anti-inflammatory activity in lipopolysaccharide-activated RAW264.7 murine macrophages and animal models of acute inflammation. Pharmaceutical biology\| PubMed ID: 31070535	2018
Total flavonoids from sea buckthorn ameliorates lipopolysaccharide/cigarette smoke-induced airway inflammation. Phytotherapy research : PTR\| PubMed ID: 31209984	2019
Anticancer activity of dietary xanthone α-mangostin against hepatocellular carcinoma by inhibition of STAT3 signaling via stabilization of SHP1. Cell death & disease\| PubMed ID: 31980595	2020
Corrigendum to "A new xanthatin analogue 1β-hydroxyl-5α-chloro-8-epi-xanthatin induces apoptosis through ROS-mediated ERK/p38 MAPK activation and JAK2/STAT3 inhibition in human hepatocellula... Biochimie\| PubMed ID: 32058161	2020
Ferroptosis inhibitory constituents from the fruits of . Natural product research\| PubMed ID: 32375513	2021
Costunolide improved dextran sulfate sodium-induced acute ulcerative colitis in mice through NF-κB, STAT1/3, and Akt signaling pathways. International immunopharmacology\| PubMed ID: 32413737	2020
Terpenoid and phenolic derivatives from the aerial parts of Elsholtzia rugulosa and their anti-inflammatory activity. Phytochemistry\| PubMed ID: 33161176	2021
Targeting Endosomal Recycling Pathways by Bacterial and Viral Pathogens. Frontiers in cell and developmental biology\| PubMed ID: 33748141	2021
Steroidal alkaloids from the bulbs of Fritillaria pallidiflora Schrenk and their anti-inflammatory activity. Bioorganic chemistry\| PubMed ID: 33812268	2021
Anti-Apoptotic Role of Sanhuang Xiexin Decoction and Anisodamine in Endotoxemia. Frontiers in pharmacology\| PubMed ID: 33967742	2021
Model-based analysis uncovers mutations altering autophagy selectivity in human cancer. Nature communications\| PubMed ID: 34059679	2021
Sesquiterpene Lactones from Possessing Potent Anti-inflammatory Activity by Directly Binding to IKKα/β. Journal of natural products\| PubMed ID: 34726063	2021
Dehydrocostus Lactone Suppresses Dextran Sulfate Sodium-Induced Colitis by Targeting the IKKα/β-NF-κB and Keap1-Nrf2 Signalling Pathways. Frontiers in pharmacology\| PubMed ID: 35321327	2022
Discovery of diarylheptanoids that activate α7 nAchR-JAK2-STAT3 signaling in macrophages with anti-inflammatory activity in vitro and in vivo. Bioorganic & medicinal chemistry\| PubMed ID: 35576655	2022
Brevilin A Ameliorates Acute Lung Injury and Inflammation Through Inhibition of NF-κB Signaling Targeting IKKα/β. Frontiers in pharmacology\| PubMed ID: 35774606	2022
The use of traditional Chinese medicines in relieving exercise-induced fatigue. Frontiers in pharmacology\| PubMed ID: 35935864	2022
Eupalinolide B attenuates lipopolysaccharide-induced acute lung injury through inhibition of NF-κB and MAPKs signaling by targeting TAK1 protein. International immunopharmacology\| PubMed ID: 35988521	2022
Searching for Novel Noncovalent Nuclear Export Inhibitors through a Drug Repurposing Approach. Journal of medicinal chemistry\| PubMed ID: 36622814	2023
A natural chalcone cardamonin inhibits necroptosis and ameliorates dextran sulfate sodium (DSS)-induced colitis by targeting RIPK1/3 kinases. European journal of pharmacology\| PubMed ID: 37302524	2023
Scutellarein alleviates chronic obstructive pulmonary disease through inhibition of ferroptosis by chelating iron and interacting with arachidonate 15-lipoxygenase. Phytotherapy research : PTR\| PubMed ID: 37353982	2023
Discovery of Aminoratjadone Derivatives as Potent Noncovalent CRM1 Inhibitors. Journal of medicinal chemistry\| PubMed ID: 37595020	2023
A natural sesquiterpene lactone isolinderalactone attenuates lipopolysaccharide-induced inflammatory response and acute lung injury through inhibition of NF-κB pathway and activation Nrf2 pa... International immunopharmacology\| PubMed ID: 37741124	2023
Mollugin prevents CLP-induced sepsis in mice by inhibiting TAK1-NF-κB/MAPKs pathways and activating Keap1-Nrf2 pathway in macrophages. International immunopharmacology\| PubMed ID: 38149576	2023
Arteannuin B, a sesquiterpene lactone from Artemisia annua, attenuates inflammatory response by inhibiting the ubiquitin-conjugating enzyme UBE2D3-mediated NF-κB activation. Phytomedicine : international journal of phytotherapy and phytopharmacology\| PubMed ID: 38181532	2024
TBK1, a prioritized drug repurposing target for amyotrophic lateral sclerosis: evidence from druggable genome Mendelian randomization and pharmacological verification in vitro. BMC medicine\| PubMed ID: 38443977	2024
Echinatin attenuates acute lung injury and inflammatory responses via TAK1-MAPK/NF-κB and Keap1-Nrf2-HO-1 signaling pathways in macrophages. PloS one\| PubMed ID: 38753858	2024
The potential application and molecular mechanisms of natural products in the treatment of allergic rhinitis: A review. Phytomedicine : international journal of phytotherapy and phytopharmacology\| PubMed ID: 38759345	2024
The cellular and molecular targets of natural products against metabolic disorders: a translational approach to reach the bedside. MedComm\| PubMed ID: 39049964	2024
Sea buckthorn extract mitigates chronic obstructive pulmonary disease by suppression of ferroptosis via scavenging ROS and blocking p53/MAPK pathways. Journal of ethnopharmacology\| PubMed ID: 39181279	2025
Demethylzeylasteral alleviates inflammation and colitis via dual suppression of NF-κB and STAT3/5 by targeting IKKα/β and JAK2. International immunopharmacology\| PubMed ID: 39340986	2024
Protein kinase a suppresses antiproliferative effect of interferon-α in hepatocellular carcinoma by activation of protein tyrosine phosphatase SHP2. The Journal of biological chemistry\| PubMed ID: 39826687	2025
Sesquiterpene lactones from Cichorium intybus exhibit potent anti-inflammatory and hepatoprotective effects by repression of NF-κB and enhancement of NRF2. Journal of ethnopharmacology\| PubMed ID: 39904423	2025
Network pharmacology integrated with experimental validation reveals the mechanism of Xanthii Fructus against allergic rhinitis via JAK2/STAT3/HIF-1α signaling pathway. Journal of ethnopharmacology\| PubMed ID: 39923957	2025
Senkyunolide I alleviates allergic rhinitis by inhibiting JAK1/3-STAT3/6 and JNK signalings. International immunopharmacology\| PubMed ID: 40911991	2025
Phytochemical and biological studies on rare and endangered plants endemic to China. Part XLVII. Sesquiterpene lactones from the leaves of Michelia opipara and their anti-inflammation effect... Phytochemistry\| PubMed ID: 41015070	2026
Toosendanin inhibits STING signaling pathway to alleviate ulcerative colitis via blocking LYN kinase and STING protein. Biochemical pharmacology\| PubMed ID: 41187884	2026
Covalently targeting HSP90 with a natural small-molecule costunolide to inhibit necroptosis and ulcerative colitis. International immunopharmacology\| PubMed ID: 41687519	2026