Shengdian Wang

Laboratory of Biomacromolecules, Chinese Academy of Sciences

Affiliated withChinese Academy of Sciences

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2026

Other Publications

Article	Year
B7-H1 up-regulation on myeloid dendritic cells significantly suppresses T cell immune function in patients with chronic hepatitis B. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17475895	2007
Immunobiology of cancer therapies targeting CD137 and B7-H1/PD-1 cosignal pathways. Current topics in microbiology and immunology\| PubMed ID: 20582531	2011
Structural immunology of costimualtory and coinhibitory molecules. Science China. Life sciences\| PubMed ID: 20596825	2010
The therapeutic effect of anti-HER2/neu antibody depends on both innate and adaptive immunity. Cancer cell\| PubMed ID: 20708157	2010
Development and characterization of monoclonal antibodies against mouse TSLP. Hybridoma (2005)\| PubMed ID: 21050044	2010
CD137-mediated pathogenesis from chronic hepatitis to hepatocellular carcinoma in hepatitis B virus-transgenic mice. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21059892	2010
Interleukin-6 induces Gr-1+CD11b+ myeloid cells to suppress CD8+ T cell-mediated liver injury in mice. PloS one\| PubMed ID: 21394214	2011
The development and functions of CD4(+) T cells expressing a transgenic TCR specific for an MHC-I-restricted tumor antigenic epitope. Cellular & molecular immunology\| PubMed ID: 21643003	2011
The tumor immunosuppressive microenvironment impairs the therapy of anti-HER2/neu antibody. Protein & cell\| PubMed ID: 22717982	2012
Effective anti-neu-initiated antitumor responses require the complex role of CD4+ T cells. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 23363817	2013
Induction of regulatory T cells by high-dose gp96 suppresses murine liver immune hyperactivation. PloS one\| PubMed ID: 23874845	2013
IL-21 accelerates xenogeneic graft-versus-host disease correlated with increased B-cell proliferation. Protein & cell\| PubMed ID: 24214876	2013
Transthyretin as a novel candidate biomarker for preeclampsia. Experimental and therapeutic medicine\| PubMed ID: 24940434	2014
Hyper-IL-15 suppresses metastatic and autochthonous liver cancer by promoting tumour-specific CD8+ T cell responses. Journal of hepatology\| PubMed ID: 25016226	2014
S100A4 promotes liver fibrosis via activation of hepatic stellate cells. Journal of hepatology\| PubMed ID: 25111176	2015
Proteomics analysis for finding serum markers of ovarian cancer. BioMed research international\| PubMed ID: 25250314	2014
A vaccinia virus armed with interleukin-10 is a promising therapeutic agent for treatment of murine pancreatic cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 25416195	2015
Granzyme M expressed by tumor cells promotes chemoresistance and EMT in vitro and metastasis in vivo associated with STAT3 activation. Oncotarget\| PubMed ID: 25788270	2015
Intratumoral Delivery of IL-21 Overcomes Anti-Her2/Neu Resistance through Shifting Tumor-Associated Macrophages from M2 to M1 Phenotype. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 25876763	2015
Immunotherapy of metastatic and autochthonous liver cancer with IL-15/IL-15Rα fusion protein. Oncoimmunology\| PubMed ID: 25941592	2014
Expression of the galectin-9-Tim-3 pathway in glioma tissues is associated with the clinical manifestations of glioma. Oncology letters\| PubMed ID: 26998085	2016
Antibody Therapies in Cancer. Advances in experimental medicine and biology\| PubMed ID: 27240456	2016
A novel peptide targeting Clec9a on dendritic cell for cancer immunotherapy. Oncotarget\| PubMed ID: 27250027	2016
The efficacy of oncolytic adenovirus is mediated by T cell responses against virus and tumor in Syrian hamster model. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 27435398	2016
B7-DC (PD-L2) costimulation of CD4 T-helper 1 response via RGMb. Cellular & molecular immunology\| PubMed ID: 28479601	2018
Author Correction: Re-designing Interleukin-12 to enhance its safety and potential as an anti-tumor immunotherapeutic agent. Nature communications\| PubMed ID: 29321470	2018
CD24-p53 axis suppresses diethylnitrosamine-induced hepatocellular carcinogenesis by sustaining intrahepatic macrophages. Cell discovery\| PubMed ID: 29423273	2018
S100A4 blockage alleviates agonistic anti-CD137 antibody-induced liver pathology without disruption of antitumor immunity. Oncoimmunology\| PubMed ID: 29632708	2018
Arthritis of large joints shown as a rare clinical feature of cytokine release syndrome after chimeric antigen receptor T cell therapy: A case report. Medicine\| PubMed ID: 29668614	2018
Vacuolar Protein Sorting 33B Is a Tumor Suppressor in Hepatocarcinogenesis. Hepatology (Baltimore, Md.)\| PubMed ID: 29729199	2018
First-in-class immune-modulating small molecule Icaritin in advanced hepatocellular carcinoma: preliminary results of safety, durable survival and immune biomarkers. BMC cancer\| PubMed ID: 30922248	2019
NKG2A is a NK cell exhaustion checkpoint for HCV persistence. Nature communications\| PubMed ID: 30944315	2019
A Virus-Infected, Reprogrammed Somatic Cell-Derived Tumor Cell (VIReST) Vaccination Regime Can Prevent Initiation and Progression of Pancreatic Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 31767564	2020
S-15 in combination of Akt inhibitor promotes the expansion of CD45RACCR7 tumor infiltrating lymphocytes with high cytotoxic potential and downregulating PD-1Tim-3 cells as well as regulator... Cancer cell international\| PubMed ID: 31827396	2019
A preliminary study on serological assay for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 238 admitted hospital patients. Microbes and infection\| PubMed ID: 32425648	2020
The Prognostic Value of EMT in Glioma and its Role in the Glioma Immune Microenvironment. Journal of molecular neuroscience : MN\| PubMed ID: 32495005	2020
Neutrophil-to-lymphocyte ratio, a critical predictor for assessment of disease severity in patients with COVID-19. International journal of laboratory hematology\| PubMed ID: 33099889	2021
A novel workflow for cancer blood biomarker identification. Annals of translational medicine\| PubMed ID: 33313175	2020
Targeting IL-21 to tumor-reactive T cells enhances memory T cell responses and anti-PD-1 antibody therapy. Nature communications\| PubMed ID: 33574265	2021
Glucose limitation activates AMPK coupled SENP1-Sirt3 signalling in mitochondria for T cell memory development. Nature communications\| PubMed ID: 34272364	2021
Correction to: CD163+CD14+ macrophages, a potential immune biomarker for malignant pleural effusion. Cancer immunology, immunotherapy : CII\| PubMed ID: 34347147	2021
High Mobility Group Protein B1 Decreases Surface Localization of PD-1 to Augment T-cell Activation. Cancer immunology research\| PubMed ID: 35580259	2022
Glucocorticoid-induced expansion of classical monocytes contributes to bone loss. Experimental & molecular medicine\| PubMed ID: 35672449	2022
Epithelial-mesenchymal transition is the main way in which glioma-associated microglia/macrophages promote glioma progression. Frontiers in immunology\| PubMed ID: 36969175	2023
Oncolytic virus Ad-TD-nsIL-12 inhibits glioma growth and reprograms the tumor immune microenvironment. Life sciences\| PubMed ID: 37977355	2024
Tumor-derived IL-6 promotes chordoma invasion by stimulating tumor-associated macrophages M2 polarization and TNFα secretion. International immunopharmacology\| PubMed ID: 39393273	2024
Non-secreting IL12 expressing oncolytic adenovirus Ad-TD-nsIL12 in recurrent high-grade glioma: a phase I trial. Nature communications\| PubMed ID: 39516192	2024
Rs61731397-C in OR2A25 increases the risk of chronic rhinosinusitis in the Chinese population. The Journal of allergy and clinical immunology\| PubMed ID: 40669566	2025
The oncolytic adenovirus Ad-TD-nsIL12 in primary or progressive pediatric IDH wild-type diffuse intrinsic pontine glioma results of two phase I clinical trials. Nature communications\| PubMed ID: 40721414	2025
TCR-NF-κB signaling activates the SENP1-NR4A1 axis to fine-tune effector activation of CD8 T cells. Cell reports\| PubMed ID: 41831233	2026