detecting-inter-individual-contamination-mismatches-multiomics-next

Detecting Inter-Individual Contamination and Mismatches in Multiomics Next-Generation Sequencing Data

High-throughput processing of patient biosamples by next-generation sequencing and the comparison of molecular data with patient-level and sample-level ...

Genentech Research and Early Development

Rancho Biosciences, LLC

PIK3CA mutations frequently drive solid tumors, particularly hormone receptor-positive breast cancer. Inavolisib, an ATP-competitive p110α inhibitor, also promotes the degradation of mutated p110α. PI3K inhibitors have generally shown modest single-agent activity and have safety concerns.

Zachary Whitfield

Biography

JoVE Journal Publications

Other Publications