Mikala Egeblad

Cold Spring Harbor Laboratory

Affiliated withCold Spring Harbor Laboratory

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 15	2013
Publication title Cited by 9	2022

Other Publications

Article	Year
New functions for the matrix metalloproteinases in cancer progression. Nature reviews. Cancer\| PubMed ID: 11990853	2002
Ets2-dependent stromal regulation of mouse mammary tumors. Molecular and cellular biology\| PubMed ID: 14612405	2003
Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14668450	2003
Truncation of activated leukocyte cell adhesion molecule: a gateway to melanoma metastasis. The Journal of investigative dermatology\| PubMed ID: 15140234	2004
Coevolution of cancer and stromal cellular responses. Cancer cell\| PubMed ID: 15950897	2005
Proteolytic cleavage and phosphorylation of a tumor-associated ErbB4 isoform promote ligand-independent survival and cancer cell growth. Molecular biology of the cell\| PubMed ID: 16251361	2006
Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer. Neoplasia (New York, N.Y.)\| PubMed ID: 16331886	2005
Type I collagen is a genetic modifier of matrix metalloproteinase 2 in murine skeletal development. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 17440987	2007
GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model. Cancer cell\| PubMed ID: 18242514	2008
Matrix metalloproteinase 13 is induced in fibroblasts in polyomavirus middle T antigen-driven mammary carcinoma without influencing tumor progression. PloS one\| PubMed ID: 18698413	2008
Visualizing stromal cell dynamics in different tumor microenvironments by spinning disk confocal microscopy. Disease models & mechanisms\| PubMed ID: 19048079	2008
Matrix crosslinking forces tumor progression by enhancing integrin signaling. Cell\| PubMed ID: 19931152	2009
Stromal regulation of vessel stability by MMP14 and TGFbeta. Disease models & mechanisms\| PubMed ID: 20223936	2010
Tumors as organs: complex tissues that interface with the entire organism. Developmental cell\| PubMed ID: 20627072	2010
Dynamic interplay between the collagen scaffold and tumor evolution. Current opinion in cell biology\| PubMed ID: 20822891	2010
Preparation of mice for long-term intravital imaging of the mammary gland. Cold Spring Harbor protocols\| PubMed ID: 21285262	2011
Monitoring of vital signs for long-term survival of mice under anesthesia. Cold Spring Harbor protocols\| PubMed ID: 21285263	2011
Dynamic, long-term in vivo imaging of tumor-stroma interactions in mouse models of breast cancer using spinning-disk confocal microscopy. Cold Spring Harbor protocols\| PubMed ID: 21285277	2011
Innate immune cells in breast cancer--from villains to heroes? Journal of mammary gland biology and neoplasia\| PubMed ID: 21789554	2011
Marginating dendritic cells of the tumor microenvironment cross-present tumor antigens and stably engage tumor-specific T cells. Cancer cell\| PubMed ID: 22439936	2012
Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance. Cancer cell\| PubMed ID: 22516258	2012
Caught in the act: revealing the metastatic process by live imaging. Disease models & mechanisms\| PubMed ID: 23616077	2013
System-wide analysis reveals a complex network of tumor-fibroblast interactions involved in tumorigenicity. PLoS genetics\| PubMed ID: 24068959	2013
Cancer: Sugar-coated cell signalling. Nature\| PubMed ID: 25030162	2014
Presence of insulin-like growth factor binding proteins correlates with tumor-promoting effects of matrix metalloproteinase 9 in breast cancer. Neoplasia (New York, N.Y.)\| PubMed ID: 26025665	2015
Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss. Genes & development\| PubMed ID: 26701265	2016
Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps. Science translational medicine\| PubMed ID: 27798263	2016
EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth. Journal of hematology & oncology\| PubMed ID: 28103946	2017
Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer. The Journal of experimental medicine\| PubMed ID: 28232471	2017
Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis. Cell\| PubMed ID: 28757253	2017
Re-cyclin' Cell-Cycle Components to Make NETs. Developmental cell\| PubMed ID: 29161586	2017
Bone Talk: Activated Osteoblasts Promote Lung Cancer Growth. Trends in molecular medicine\| PubMed ID: 29402707	2018
Unresolved endoplasmic reticulum stress engenders immune-resistant, latent pancreatic cancer metastases. Science (New York, N.Y.)\| PubMed ID: 29773669	2018
POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer. Genes & development\| PubMed ID: 29945888	2018
Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice. Science (New York, N.Y.)\| PubMed ID: 30262472	2018
Transcriptomic profiles conducive to immune-mediated tumor rejection in human breast cancer skin metastases treated with Imiquimod. Scientific reports\| PubMed ID: 31189943	2019
Tumours pick the path to cancer inflammation. Nature cell biology\| PubMed ID: 31451769	2019
Stressing Out about Cancer Immunotherapy. Cancer cell\| PubMed ID: 31715130	2019
Communication in tiny packages: Exosomes as means of tumor-stroma communication. Biochimica et biophysica acta. Reviews on cancer\| PubMed ID: 31926290	2020
The entry of nanoparticles into solid tumours. Nature materials\| PubMed ID: 31932672	2020
A framework for advancing our understanding of cancer-associated fibroblasts. Nature reviews. Cancer\| PubMed ID: 31980749	2020
Targeting potential drivers of COVID-19: Neutrophil extracellular traps. The Journal of experimental medicine\| PubMed ID: 32302401	2020
Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation. eLife\| PubMed ID: 32329713	2020
Neutrophil extracellular traps in COVID-19. JCI insight\| PubMed ID: 32329756	2020
Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: A case series. medRxiv : the preprint server for health sciences\| PubMed ID: 32511514	2020
Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome. Blood\| PubMed ID: 32597954	2020
Cancer cell CCR2 orchestrates suppression of the adaptive immune response. The Journal of experimental medicine\| PubMed ID: 32667673	2020
A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis. Nature communications\| PubMed ID: 32788676	2020
Gut Feelings Block the Flow: Microbiota Links Stress to Vascular Disease. Immunity\| PubMed ID: 32814021	2020
Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: a case series. Molecular medicine (Cambridge, Mass.)\| PubMed ID: 32993479	2020
Frontiers in cancer immunotherapy-a symposium report. Annals of the New York Academy of Sciences\| PubMed ID: 33184911	2021
Patients with COVID-19: in the dark-NETs of neutrophils. Cell death and differentiation\| PubMed ID: 34031543	2021
Multi-color Flow Cytometry for Comprehensive Analysis of the Tumor Immune Infiltrate in a Murine Model of Breast Cancer. Bio-protocol\| PubMed ID: 34250200	2021
Treatment with Granulocyte-colony Stimulating Factor (G-CSF) is not associated with Increased Risk of Brain Metastasis in Patients with Stage IV Breast Cancer. Journal of Cancer\| PubMed ID: 34405029	2021
Activating a collaborative innate-adaptive immune response to control metastasis. Cancer cell\| PubMed ID: 34478639	2021
A Bivalent Activatable Fluorescent Probe for Screening and Intravital Imaging of Chemotherapy-Induced Cancer Cell Death. Angewandte Chemie (International ed. in English)\| PubMed ID: 34762762	2021
Innate Immunity and Cancer Pathophysiology. Annual review of pathology\| PubMed ID: 34788549	2021