Dongsheng Duan

Department of Molecular Microbiology and Immunology, University of Missouri

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 75	2013

Other Publications

Article	Year
Modular flexibility of dystrophin: implications for gene therapy of Duchenne muscular dystrophy. Nature medicine\| PubMed ID: 11875496	2002
Recombinant AAV-mediated gene delivery using dual vector heterodimerization. Methods in enzymology\| PubMed ID: 11883078	2002
Development of multiple cloning site cis-vectors for recombinant adeno-associated virus production. BioTechniques\| PubMed ID: 12238777	2002
Trans-splicing vectors expand the packaging limits of adeno-associated virus for gene therapy applications. Methods in molecular medicine\| PubMed ID: 12526170	2003
Dual vector expansion of the recombinant AAV packaging capacity. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 12596997	2003
Consequences of DNA-dependent protein kinase catalytic subunit deficiency on recombinant adeno-associated virus genome circularization and heterodimerization in muscle tissue. Journal of virology\| PubMed ID: 12663782	2003
Adenovirus-mediated gene transfer to adult mouse cardiomyocytes is selectively influenced by culture medium. The journal of gene medicine\| PubMed ID: 12950067	2003
Double strand interaction is the predominant pathway for intermolecular recombination of adeno-associated viral genomes. Virology\| PubMed ID: 12951015	2003
Microdystrophin gene therapy of cardiomyopathy restores dystrophin-glycoprotein complex and improves sarcolemma integrity in the mdx mouse heart. Circulation\| PubMed ID: 12952841	2003
Full-length dystrophin expression in half of the heart cells ameliorates beta-isoproterenol-induced cardiomyopathy in mdx mice. Human molecular genetics\| PubMed ID: 15190010	2004
Trans-splicing adeno-associated viral vector-mediated gene therapy is limited by the accumulation of spliced mRNA but not by dual vector coinfection efficiency. Human gene therapy\| PubMed ID: 15353044	2004
Adeno-associated virus-mediated microdystrophin expression protects young mdx muscle from contraction-induced injury. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 15668136	2005
Efficient in vivo gene expression by trans-splicing adeno-associated viral vectors. Nature biotechnology\| PubMed ID: 16244658	2005
Viral serotype and the transgene sequence influence overlapping adeno-associated viral (AAV) vector-mediated gene transfer in skeletal muscle. The journal of gene medicine\| PubMed ID: 16385549	2006
C-terminal-truncated microdystrophin recruits dystrobrevin and syntrophin to the dystrophin-associated glycoprotein complex and reduces muscular dystrophy in symptomatic utrophin/dystrophin ... Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 16563874	2006
Challenges and opportunities in dystrophin-deficient cardiomyopathy gene therapy. Human molecular genetics\| PubMed ID: 16987891	2006
Synthetic intron improves transduction efficiency of trans-splicing adeno-associated viral vectors. Human gene therapy\| PubMed ID: 17007565	2006
From the smallest virus to the biggest gene: marching towards gene therapy for duchenne muscular dystrophy. Discovery medicine\| PubMed ID: 17234143	2006
Efficient whole-body transduction with trans-splicing adeno-associated viral vectors. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 17264855	2007
Catalase overexpression does not impair extensor digitorum longus muscle function in normal mice. Muscle & nerve\| PubMed ID: 17696155	2007
Prevention of dystrophin-deficient cardiomyopathy in twenty-one-month-old carrier mice by mosaic dystrophin expression or complementary dystrophin/utrophin expression. Circulation research\| PubMed ID: 17967782	2008
A hybrid vector system expands adeno-associated viral vector packaging capacity in a transgene-independent manner. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 17984978	2008
Expanding adeno-associated viral vector capacity: a tale of two vectors. Biotechnology & genetic engineering reviews\| PubMed ID: 18059632	2007
Myodys, a full-length dystrophin plasmid vector for Duchenne and Becker muscular dystrophy gene therapy. Current opinion in molecular therapeutics\| PubMed ID: 18228186	2008
Preservation of muscle force in Mdx3cv mice correlates with low-level expression of a near full-length dystrophin protein. The American journal of pathology\| PubMed ID: 18385524	2008
Adeno-associated virus serotype-9 microdystrophin gene therapy ameliorates electrocardiographic abnormalities in mdx mice. Human gene therapy\| PubMed ID: 18666839	2008
Design of trans-splicing adeno-associated viral vectors for Duchenne muscular dystrophy gene therapy. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 18679629	2008
Dystrophin knockdown mice suggest that early, transient dystrophin expression might be enough to prevent later pathology. Neuromuscular disorders : NMD\| PubMed ID: 18818078	2008
A single intravenous injection of adeno-associated virus serotype-9 leads to whole body skeletal muscle transduction in dogs. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 18827804	2008
Cardiac expression of a mini-dystrophin that normalizes skeletal muscle force only partially restores heart function in aged Mdx mice. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 19066599	2009
Sub-physiological sarcoglycan expression contributes to compensatory muscle protection in mdx mice. Human molecular genetics\| PubMed ID: 19131360	2009
Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy. The Journal of clinical investigation\| PubMed ID: 19229108	2009
Adeno-associated virus serotype-9 efficiently transduces the retinal outer plexiform layer. Molecular vision\| PubMed ID: 19626133	2009
Systemic Trans-splicing adeno-associated viral delivery efficiently transduces the heart of adult mdx mouse, a model for duchenne muscular dystrophy. Human gene therapy\| PubMed ID: 19627234	2009
Ectopic catalase expression in mitochondria by adeno-associated virus enhances exercise performance in mice. PloS one\| PubMed ID: 19690612	2009
Evidence for the failure of adeno-associated virus serotype 5 to package a viral genome > or = 8.2 kb. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 19904238	2010
Adeno-associated virus serotype-9 mediated retinal outer plexiform layer transduction is mainly through the photoreceptors. Advances in experimental medicine and biology\| PubMed ID: 20238072	2010
Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin. Journal of cell science\| PubMed ID: 20483958	2010
Adeno-associated virus serotype 6 capsid tyrosine-to-phenylalanine mutations improve gene transfer to skeletal muscle. Human gene therapy\| PubMed ID: 20497037	2010
Efficient transgene reconstitution with hybrid dual AAV vectors carrying the minimized bridging sequences. Human gene therapy\| PubMed ID: 20662564	2011
An intronic LINE-1 element insertion in the dystrophin gene aborts dystrophin expression and results in Duchenne-like muscular dystrophy in the corgi breed. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 20714321	2011
Gender influences cardiac function in the mdx model of Duchenne cardiomyopathy. Muscle & nerve\| PubMed ID: 20878741	2010
Evidence for impaired neurovascular transmission in a murine model of Duchenne muscular dystrophy. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 21109597	2011
Nitrosative stress elicited by nNOSÂµ delocalization inhibits muscle force in dystrophin-null mice. The Journal of pathology\| PubMed ID: 21125668	2011
Marginal level dystrophin expression improves clinical outcome in a strain of dystrophin/utrophin double knockout mice. PloS one\| PubMed ID: 21187970	2010
Monitoring murine skeletal muscle function for muscle gene therapy. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21194022	2011
Phenotyping cardiac gene therapy in mice. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21194023	2011
Whole body skeletal muscle transduction in neonatal dogs with AAV-9. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21194038	2011
Genotyping mdx, mdx3cv, and mdx4cv mice by primer competition polymerase chain reaction. Muscle & nerve\| PubMed ID: 21254096	2011
The passive mechanical properties of the extensor digitorum longus muscle are compromised in 2- to 20-mo-old mdx mice. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 21415170	2011
Age-matched comparison reveals early electrocardiography and echocardiography changes in dystrophin-deficient dogs. Neuromuscular disorders : NMD\| PubMed ID: 21570848	2011
Duchenne muscular dystrophy gene therapy: Lost in translation? Research and reports in biology\| PubMed ID: 21691429	2011
iNOS ablation does not improve specific force of the extensor digitorum longus muscle in dystrophin-deficient mdx4cv mice. PloS one\| PubMed ID: 21738735	2011
AAV-microdystrophin therapy improves cardiac performance in aged female mdx mice. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 21811246	2011
SERCA2a gene transfer improves electrocardiographic performance in aged mdx mice. Journal of translational medicine\| PubMed ID: 21834967	2011
The evolution of heart gene delivery vectors. The journal of gene medicine\| PubMed ID: 21837689	2011
Novel mini-dystrophin gene dual adeno-associated virus vectors restore neuronal nitric oxide synthase expression at the sarcolemma. Human gene therapy\| PubMed ID: 21933029	2012
A Simplified Immune Suppression Scheme Leads to Persistent Micro-dystrophin Expression in Duchenne Muscular Dystrophy Dogs. Human gene therapy\| PubMed ID: 21967249	2012
Gene delivery to the heart: an updated review on vectors and methods. The journal of gene medicine\| PubMed ID: 22025443	2011
Humoral immunity to AAV-6, 8, and 9 in normal and dystrophic dogs. Human gene therapy\| PubMed ID: 22040468	2012
Recombinant adeno-associated viral vector production and purification. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 22130842	2012
Gender differences in contractile and passive properties of mdx extensor digitorum longus muscle. Muscle & nerve\| PubMed ID: 22246882	2012
AAV micro-dystrophin gene therapy alleviates stress-induced cardiac death but not myocardial fibrosis in >21-m-old mdx mice, an end-stage model of Duchenne muscular dystrophy cardiomyopathy. Journal of molecular and cellular cardiology\| PubMed ID: 22587991	2012
Dystrophin deficiency compromises force production of the extensor carpi ulnaris muscle in the canine model of Duchenne muscular dystrophy. PloS one\| PubMed ID: 22973449	2012
Î±2 and Î±3 helices of dystrophin R16 and R17 frame a microdomain in the Î±1 helix of dystrophin R17 for neuronal NOS binding. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23185009	2013
Truncated dystrophins reduce muscle stiffness in the extensor digitorum longus muscle of mdx mice. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 23221959	2012
A marginal level of dystrophin partially ameliorates hindlimb muscle passive mechanical properties in dystrophin-null mice. Muscle & nerve\| PubMed ID: 23225385	2012
Microdystrophin Ameliorates Muscular Dystrophy in the Canine Model of Duchenne Muscular Dystrophy. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 23319056	2013