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Evaluation of Muscle Function of the Extensor Digitorum Longus Muscle Ex vivo and Tibialis Anterior Muscle In situ in Mice
JoVE Journal
Biology
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JoVE Journal Biology
Evaluation of Muscle Function of the Extensor Digitorum Longus Muscle Ex vivo and Tibialis Anterior Muscle In situ in Mice

Evaluation of Muscle Function of the Extensor Digitorum Longus Muscle Ex vivo and Tibialis Anterior Muscle In situ in Mice

DOI:
10.3791/50183-v

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14:36 min

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February 09, 2013

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, ,
1Department of Molecular Microbiology and Immunology, School of Medicine,University of Missouri

Chapters

  • 00:05Title
  • 01:57Equipment Preparation and Extensor Digitorum Longus Muscle Dissection
  • 05:50Measuring the Contractile and Passive Properties of the EDL Muscle
  • 08:44Evaluation of the Contractile Properties of the TA Muscle In situ
  • 11:52Representative Contractile and Passive Muscle Measurements
  • 13:40Conclusion

Summary

Automatic Translation

Automatic Translation

Changes in limb muscle contractile and passive mechanical properties are important biomarkers for muscle diseases. This manuscript describes physiological assays to measure these properties in the murine extensor digitorum longus and tibialis anterior muscles.

Tags

Keywords: Muscle FunctionExtensor Digitorum LongusTibialis AnteriorSkeletal MuscleContractile PropertiesPassive PropertiesDuchenne Muscular DystrophyDystrophinSarcolemmaMuscle ForceFibrosis

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