Meng Wu

My primary research interests focused on molecular probe/drug lead discovery via the high-throughput screening and assay development, based on my earlier fluorescent and chemo- and bio-sensor expertise, i.e. fluorescent chemical sensors/nanosensors or label-free high throughput screening Epic platform. Furthermore, we have reputable expertise supporting assay design and development (see PubChem). Through innovative assay development and collaboration with medicinal chemists, my lab aims to discover novel potent and specific molecular probes, as well as therapeutic leads for their associated diseases.

The University of Iowa High Throughput Screening Facility (UIHTS) is a high throughput platform that integrates robotics, detection systems and chemical /biologics libraries. UIHTS enables scalable screening approaches, not only to foster hit and lead generation for drug discovery and development through screening of large chemical/biologics libraries; but also to facilitate molecular probe discovery for mechanism of action (MOA) studies of chemical biology through screening of focused intellectually-designed compound collections. As a university core facility, UIHTS provides highly flexible screening services, project management, and assay/technology development for investigators across campus as well as off-campus.