Horst Schroten

Department of Pediatrics, Heidelberg University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 15	2019

Other Publications

Article	Year
Severe gastroenteritis with secondary fever in a 10-month-old boy. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology\| PubMed ID: 19875333	2010
TNFalpha induces choroid plexus epithelial cell barrier alterations by apoptotic and nonapoptotic mechanisms. Journal of biomedicine & biotechnology\| PubMed ID: 20369072	2010
Correlation of viral load of respiratory pathogens and co-infections with disease severity in children hospitalized for lower respiratory tract infection. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology\| PubMed ID: 20646956	2010
Transcellular migration of neutrophil granulocytes through the blood-cerebrospinal fluid barrier after infection with Streptococcus suis. Journal of neuroinflammation\| PubMed ID: 21592385	2011
In vitro transcriptome analysis of porcine choroid plexus epithelial cells in response to Streptococcus suis: release of pro-inflammatory cytokines and chemokines. Microbes and infection / Institut Pasteur\| PubMed ID: 21683799	2011
Polar invasion and translocation of Neisseria meningitidis and Streptococcus suis in a novel human model of the blood-cerebrospinal fluid barrier. PloS one\| PubMed ID: 22253884	2012
Pseudomonas aeruginosa outbreak in a pediatric oncology care unit caused by an errant water jet into contaminated siphons. The Pediatric infectious disease journal\| PubMed ID: 22333699	2012
Ultra late onset group B streptococcal sepsis with acute renal failure in a child with urethral obstruction: a case report. Journal of medical case reports\| PubMed ID: 22348641	2012
Candidiasis caused by Candida kefyr in a neonate: case report. BMC infectious diseases\| PubMed ID: 22424058	2012
The role of prebiotics and probiotics in prevention and treatment of childhood infectious diseases. The Pediatric infectious disease journal\| PubMed ID: 22801095	2012
Chemotaxis of T-cells after infection of human choroid plexus papilloma cells with Echovirus 30 in an in vitro model of the blood-cerebrospinal fluid barrier. Virus research\| PubMed ID: 23000117	2012
Clinical characteristics of children with viral single- and co-infections and a petechial rash. The Pediatric infectious disease journal\| PubMed ID: 23249918	2013
Culture models to study leukocyte trafficking across the choroid plexus. Fluids and barriers of the CNS\| PubMed ID: 23305147	2013
The surface proteins InlA and InlB are interdependently required for polar basolateral invasion by Listeria monocytogenes in a human model of the blood-cerebrospinal fluid barrier. Microbes and infection / Institut Pasteur\| PubMed ID: 23376167	2013
Transmigration of polymorphnuclear neutrophils and monocytes through the human blood-cerebrospinal fluid barrier after bacterial infection in vitro. Journal of neuroinflammation\| PubMed ID: 23448224	2013
Bioengineered 2'-fucosyllactose and 3-fucosyllactose inhibit the adhesion of Pseudomonas aeruginosa and enteric pathogens to human intestinal and respiratory cell lines. Nutrition research (New York, N.Y.)\| PubMed ID: 24074741	2013
Prevalence of hepatitis E virus antibodies in children in Germany. The Pediatric infectious disease journal\| PubMed ID: 24168981	2014
Multiple aseptic splenic abscesses in a 15 year old patient. BMC gastroenterology\| PubMed ID: 24502393	2014
Human trefoil factor 2 is a lectin that binds α-GlcNAc-capped mucin glycans with antibiotic activity against Helicobacter pylori. The Journal of biological chemistry\| PubMed ID: 25124036	2014
Neisseria meningitidis elicits a pro-inflammatory response involving IκBζ in a human blood-cerebrospinal fluid barrier model. Journal of neuroinflammation\| PubMed ID: 25347003	2014
Impact of calcium signaling during infection of Neisseria meningitidis to human brain microvascular endothelial cells. PloS one\| PubMed ID: 25464500	2014
The choroid plexus-a multi-role player during infectious diseases of the CNS. Frontiers in cellular neuroscience\| PubMed ID: 25814932	2015
Severe Upper Extremity Dysfunction After 4CMenB Vaccination in a Young Infant. The Pediatric infectious disease journal\| PubMed ID: 26379162	2016
The choroid plexus may be an underestimated site of tumor invasion to the brain: an in vitro study using neuroblastoma cell lines. Cancer cell international\| PubMed ID: 26500454	2015
Anaphylaxis After Immunization of Children and Adolescents in Germany. The Pediatric infectious disease journal\| PubMed ID: 26835973	2016
Enterovirus Infections of the Central Nervous System in Children: An Update. The Pediatric infectious disease journal\| PubMed ID: 26862675	2016
Neuroinvasion and Inflammation in Viral Central Nervous System Infections. Mediators of inflammation\| PubMed ID: 27313404	2016
Biological activities of suilysin: role in Streptococcus suis pathogenesis. Future microbiology\| PubMed ID: 27357518	2016
Neutrophil extracellular trap formation in the Streptococcus suis-infected cerebrospinal fluid compartment. Cellular microbiology\| PubMed ID: 27450700	2017
Prevalence of Multidrug-Resistant Organisms in Hospitalized Pediatric Refugees in an University Children's Hospital in Germany 2015-2016. Infection control and hospital epidemiology\| PubMed ID: 27523304	2016
Neutral oligosaccharides in feces of breastfed and formula-fed infants at different ages. Glycobiology\| PubMed ID: 27613801	2016
Mitogen-activated protein kinases are required for effective infection of human choroid plexus epithelial cells by Listeria monocytogenes. Microbes and infection\| PubMed ID: 27671041	2017
Sequential transmigration of polymorphonuclear cells and naive CD3 T lymphocytes across the blood-cerebrospinal-fluid barrier in vitro following infection with Echovirus 30. Virus research\| PubMed ID: 28161477	2017
Loss of Mpdz impairs ependymal cell integrity leading to perinatal-onset hydrocephalus in mice. EMBO molecular medicine\| PubMed ID: 28500065	2017
Experimental Porcine Infection as a Representative Model for Human Toxoplasmosis. Mediators of inflammation\| PubMed ID: 28883687	2017
Interactions of antisera to different Chlamydia and Chlamydophila species with the ribosomal protein RPS27a correlate with impaired protein synthesis in a human choroid plexus papilloma cell... Immunologic research\| PubMed ID: 28913776	2017
The diverse cellular responses of the choroid plexus during infection of the central nervous system. American journal of physiology. Cell physiology\| PubMed ID: 29070490	2018
Strain-dependent effects of clinical echovirus 30 outbreak isolates at the blood-CSF barrier. Journal of neuroinflammation\| PubMed ID: 29463289	2018
Pediatric acute lymphoblastic leukemia-Conquering the CNS across the choroid plexus. Leukemia research\| PubMed ID: 30005184	2018
Capsule and fimbriae modulate the invasion of Haemophilus influenzae in a human blood-cerebrospinal fluid barrier model. International journal of medical microbiology : IJMM\| PubMed ID: 30049648	2018
Virulence factor-dependent basolateral invasion of choroid plexus epithelial cells by pathogenic Escherichia coli in vitro. FEMS microbiology letters\| PubMed ID: 30476042	2018
Murine -linked hydrocephalus is caused by hyperpermeability of the choroid plexus. EMBO molecular medicine\| PubMed ID: 30518636	2019
Pandemic GII.4 Sydney and Epidemic GII.17 Kawasaki308 Noroviruses Display Distinct Specificities for Histo-Blood Group Antigens Leading to Different Transmission Vector Dynamics in Pacific O... Frontiers in microbiology\| PubMed ID: 30542329	2018
Optimized cultivation of porcine choroid plexus epithelial cells, a blood-cerebrospinal fluid barrier model, for studying granulocyte transmigration. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 30996296	2019
Infectious causes of peripheral facial nerve palsy in children-a retrospective cohort study with long-term follow-up. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology\| PubMed ID: 31372902	2019
Review of functional in vitro models of the blood-cerebrospinal fluid barrier in leukaemia research. Journal of neuroscience methods\| PubMed ID: 31669338	2020
Virulence Factors of Meningitis-Causing Bacteria: Enabling Brain Entry across the Blood-Brain Barrier. International journal of molecular sciences\| PubMed ID: 31671896	2019
Distinct migratory pattern of naive and effector T cells through the blood-CSF barrier following Echovirus 30 infection. Journal of neuroinflammation\| PubMed ID: 31752904	2019
Human CD4 T cell subsets differ in their abilities to cross endothelial and epithelial brain barriers in vitro. Fluids and barriers of the CNS\| PubMed ID: 32008573	2020
Altered secretory and neuroprotective function of the choroid plexus in progressive multiple sclerosis. Acta neuropathologica communications\| PubMed ID: 32192527	2020
Bitter taste receptors profiling in the human blood-cerebrospinal fluid-barrier. Biochemical pharmacology\| PubMed ID: 32251676	2020
The bitter taste receptor TAS2R14 regulates resveratrol transport across the human blood-cerebrospinal fluid barrier. Biochemical pharmacology\| PubMed ID: 32272108	2020
Zika virus infects pericytes in the choroid plexus and enters the central nervous system through the blood-cerebrospinal fluid barrier. PLoS pathogens\| PubMed ID: 32357162	2020
Potential Roles and Functions of Listerial Virulence Factors during Brain Entry. Toxins\| PubMed ID: 32380697	2020
From Gene to Protein-How Bacterial Virulence Factors Manipulate Host Gene Expression During Infection. International journal of molecular sciences\| PubMed ID: 32466312	2020
Rapid spread of OXA-244-producing ST38 in Germany: insights from an integrated molecular surveillance approach; 2017 to January 2020. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin\| PubMed ID: 32613940	2020
Role of Bacterial and Host DNases on Host-Pathogen Interaction during Meningitis. International journal of molecular sciences\| PubMed ID: 32722502	2020
A 28-Day-Old Boy with Multifocal Osteomyelitis Mimicking Non-Accidental Injury. Klinische Padiatrie\| PubMed ID: 32767295	2021
Localization of ZIP14 and ZIP8 in HIBCPP Cells. Brain sciences\| PubMed ID: 32784388	2020
Non-Typeable Invade Choroid Plexus Epithelial Cells in a Polar Fashion. International journal of molecular sciences\| PubMed ID: 32785145	2020
Antibiotic utilization in hospitalized children under 2 years of age with influenza or respiratory syncytial virus infection - a comparative, retrospective analysis. BMC infectious diseases\| PubMed ID: 32807104	2020
Cadaverine and Spermine Elicit Ca Uptake in Human CP Cells via a Trace Amine-Associated Receptor 1 Dependent Pathway. Journal of molecular neuroscience : MN\| PubMed ID: 32816235	2021
Polar Infection of Echovirus-30 Causes Differential Barrier Affection and Gene Regulation at the Blood-Cerebrospinal Fluid Barrier. International journal of molecular sciences\| PubMed ID: 32872518	2020
Peripheral Facial Nerve Palsy in Children With Enterovirus Infection. The Pediatric infectious disease journal\| PubMed ID: 32932336	2020
Interactions and Signal Transduction Pathways Involved during Central Nervous System Entry by across the Blood-Brain Barriers. International journal of molecular sciences\| PubMed ID: 33233688	2020
Echovirus-30 Infection Alters Host Proteins in Lipid Rafts at the Cerebrospinal Fluid Barrier In Vitro. Microorganisms\| PubMed ID: 33321840	2020
The Choroid Plexus Is Permissive for a Preactivated Antigen-Experienced Memory B-Cell Subset in Multiple Sclerosis. Frontiers in immunology\| PubMed ID: 33574821	2020
Emergence of Macrolide-Resistant during an Outbreak in a Primary School: Clinical Characterization of Hospitalized Children. Pathogens (Basel, Switzerland)\| PubMed ID: 33802078	2021
Severe Pneumonia and Sepsis Caused by in an Adolescent. Pathogens (Basel, Switzerland)\| PubMed ID: 34200808	2021
Effect of Lipopolysaccharide-Induced Inflammatory Challenge on β-Glucuronidase Activity and the Concentration of Quercetin and Its Metabolites in the Choroid Plexus, Blood Plasma and Cerebro... International journal of molecular sciences\| PubMed ID: 34281178	2021
Invasion of the choroid plexus epithelium by Neisseria meningitidis is differently mediated by Arp2/3 signaling and possibly by dynamin dependent on the presence of the capsule. Pathogens and disease\| PubMed ID: 34410374	2021
General Characteristics of Children with Single- and Co-Infections and Febrile Seizures with a Main Focus on Respiratory Pathogens: Preliminary Results. Pathogens (Basel, Switzerland)\| PubMed ID: 34451525	2021
Capsule-dependent impact of MAPK signalling on host cell invasion and immune response during infection of the choroid plexus epithelium by Neisseria meningitidis. Fluids and barriers of the CNS\| PubMed ID: 34863201	2021
Characterization of Oxygen Levels in an Uninfected and Infected Human Blood-Cerebrospinal-Fluid-Barrier Model. Cells\| PubMed ID: 35011713	2022
Transmigration of across an blood-cerebrospinal fluid barrier. iScience\| PubMed ID: 35313698	2022
Porcine choroid plexus-Riems cell line demonstrates altered polarization of transport proteins compared with the native epithelium. American journal of physiology. Cell physiology\| PubMed ID: 35508188	2022
Immortalized human choroid plexus endothelial cells enable an advanced endothelial-epithelial two-cell type model of the choroid plexus. iScience\| PubMed ID: 35633941	2022
Oncostatin M triggers brain inflammation by compromising blood-brain barrier integrity. Acta neuropathologica\| PubMed ID: 35666306	2022
Cross-sectional seroprevalence surveys of SARS-CoV-2 antibodies in children in Germany, June 2020 to May 2021. Nature communications\| PubMed ID: 35668073	2022
Characterization of TRPV4-mediated signaling pathways in an optimized human choroid plexus epithelial cell line. American journal of physiology. Cell physiology\| PubMed ID: 35938676	2022
Risk for severe outcomes of COVID-19 and PIMS-TS in children with SARS-CoV-2 infection in Germany. European journal of pediatrics\| PubMed ID: 35962242	2022
In Vitro Models of the Blood-Cerebrospinal Fluid Barrier and Their Applications in the Development and Research of (Neuro)Pharmaceuticals. Pharmaceutics\| PubMed ID: 36015358	2022
Protocol to analyze the transmigration efficiency of T. brucei using an in vitro model of the blood-cerebrospinal fluid barrier. STAR protocols\| PubMed ID: 36103307	2022
Association of SARS-CoV-2 Seropositivity With Myalgic Encephalomyelitis and/or Chronic Fatigue Syndrome Among Children and Adolescents in Germany. JAMA network open\| PubMed ID: 36166227	2022
Different Involvement of Vimentin during Invasion by at the Blood-Brain and the Blood-Cerebrospinal Fluid Barriers In Vitro. International journal of molecular sciences\| PubMed ID: 36361697	2022
Protocol for the setup and use of a human choroid plexus endothelial-epithelial two-cell-type model. STAR protocols\| PubMed ID: 36386888	2022
The role of PLVAP in endothelial cells. Cell and tissue research\| PubMed ID: 36781482	2023
Comparing SARS-CoV-2 variants among children and adolescents in Germany: relative risk of COVID-19-related hospitalization, ICU admission and mortality. Infection\| PubMed ID: 36787015	2023
The phosphoproteome of choroid plexus epithelial cells following infection with Neisseria meningitidis. Frontiers in cellular and infection microbiology\| PubMed ID: 37065199	2023
SARS-CoV-2 sero-immunity and quality of life in children and adolescents in relation to infections and vaccinations: the IMMUNEBRIDGE KIDS cross-sectional study, 2022. Infection\| PubMed ID: 37280412	2023
Corrigendum: The phosphoproteome of choroid plexus epithelial cells following infection with Neisseria meningitidis. Frontiers in cellular and infection microbiology\| PubMed ID: 37637459	2023
SARS-CoV-2 infects epithelial cells of the blood-cerebrospinal fluid barrier rather than endothelial cells or pericytes of the blood-brain barrier. Fluids and barriers of the CNS\| PubMed ID: 37875964	2023
In vitro models of the choroid plexus and the blood-cerebrospinal fluid barrier: advances, applications, and perspectives. Human cell\| PubMed ID: 39103559	2024
Activation of Wnt/β-catenin signaling is critical for the tumorigenesis of choroid plexus. Neuro-oncology\| PubMed ID: 39215664	2025
Characterization of thyroid hormone transport in a human choroid plexus papilloma cell line (HIBCPP) as an in vitro blood-cerebrospinal fluid barrier model. Molecular and cellular endocrinology\| PubMed ID: 39740754	2025
Transcriptome and Functional Comparison of Primary and Immortalized Endothelial Cells of the Human Choroid Plexus at the Blood-Cerebrospinal Fluid Barrier. International journal of molecular sciences\| PubMed ID: 40004242	2025
A pH-sensitive binding modality allows successful transferrin receptor-mediated transcytosis of a bivalent antibody across brain barriers. mAbs\| PubMed ID: 40983601	2025
Genotype-dependent cell tropism of EV-A71 at the human blood cerebrospinal fluid and blood brain barrier. Microbial pathogenesis\| PubMed ID: 41135722	2025