Bruce A. Vallance

Division of Gastroenterology, BC Children's Hospital

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 65	2013
Publication title Cited by 92	2014

Other Publications

Article	Year
Mice lacking T and B lymphocytes develop transient colitis and crypt hyperplasia yet suffer impaired bacterial clearance during Citrobacter rodentium infection. Infection and immunity\| PubMed ID: 11895973	2002
Salmonella effectors within a single pathogenicity island are differentially expressed and translocated by separate type III secretion systems. Molecular microbiology\| PubMed ID: 11918798	2002
Modulation of inducible nitric oxide synthase expression by the attaching and effacing bacterial pathogen citrobacter rodentium in infected mice. Infection and immunity\| PubMed ID: 12379723	2002
Host-pathogen interactions: Host resistance factor Nramp1 up-regulates the expression of Salmonella pathogenicity island-2 virulence genes. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12441401	2002
Enteropathogenic and enterohemorrhagic Escherichia coli infections: emerging themes in pathogenesis and prevention. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 12464970	2002
SopD2 is a novel type III secreted effector of Salmonella typhimurium that targets late endocytic compartments upon delivery into host cells. Traffic (Copenhagen, Denmark)\| PubMed ID: 12535274	2003
Citrobacter rodentium translocated intimin receptor (Tir) is an essential virulence factor needed for actin condensation, intestinal colonization and colonic hyperplasia in mice. Molecular microbiology\| PubMed ID: 12657048	2003
Host susceptibility to the attaching and effacing bacterial pathogen Citrobacter rodentium. Infection and immunity\| PubMed ID: 12761129	2003
SseA is required for translocation of Salmonella pathogenicity island-2 effectors into host cells. Microbes and infection / Institut Pasteur\| PubMed ID: 12787732	2003
Salmonella type III effectors PipB and PipB2 are targeted to detergent-resistant microdomains on internal host cell membranes. Molecular microbiology\| PubMed ID: 12864852	2003
Current progress in enteropathogenic and enterohemorrhagic Escherichia coli vaccines. Expert review of vaccines\| PubMed ID: 12901587	2002
Dissecting virulence: systematic and functional analyses of a pathogenicity island. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14988506	2004
Toll-like receptor 4 dependence of innate and adaptive immunity to Salmonella: importance of the Kupffer cell network. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15128808	2004
Clearance of Citrobacter rodentium requires B cells but not secretory immunoglobulin A (IgA) or IgM antibodies. Infection and immunity\| PubMed ID: 15155635	2004
Relative contributions of NOS isoforms during experimental colitis: endothelial-derived NOS maintains mucosal integrity. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 15217783	2004
SseK1 and SseK2 are novel translocated proteins of Salmonella enterica serovar typhimurium. Infection and immunity\| PubMed ID: 15322005	2004
Myenteric plexus injury and apoptosis in experimental colitis. Autonomic neuroscience : basic & clinical\| PubMed ID: 15620569	2005
TGF-beta1 gene transfer to the mouse colon leads to intestinal fibrosis. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 15778431	2005
Modulation of host cytoskeleton function by the enteropathogenic Escherichia coli and Citrobacter rodentium effector protein EspG. Infection and immunity\| PubMed ID: 15845460	2005
Salmonella enterica serovar Typhimurium pathogenicity island 2 is necessary for complete virulence in a mouse model of infectious enterocolitis. Infection and immunity\| PubMed ID: 15908346	2005
Cloning vectors and fluorescent proteins can significantly inhibit Salmonella enterica virulence in both epithelial cells and macrophages: implications for bacterial pathogenesis studies. Infection and immunity\| PubMed ID: 16177386	2005
Salmonella pathogenicity island 2 is expressed prior to penetrating the intestine. PLoS pathogens\| PubMed ID: 16304611	2005
Noradrenergic and cholinergic neural pathways mediate stress-induced reactivation of colitis in the rat. Autonomic neuroscience : basic & clinical\| PubMed ID: 16464645	2006
Toll-like receptor 4 contributes to colitis development but not to host defense during Citrobacter rodentium infection in mice. Infection and immunity\| PubMed ID: 16622187	2006
Citrobacter rodentium infection causes both mitochondrial dysfunction and intestinal epithelial barrier disruption in vivo: role of mitochondrial associated protein (Map). Cellular microbiology\| PubMed ID: 16759225	2006
Genetic profiling of dendritic cells exposed to live- or ultraviolet-irradiated Chlamydia muridarum reveals marked differences in CXC chemokine profiles. Immunology\| PubMed ID: 17073942	2007
IL-4 gene transfer to the small bowel serosa leads to intestinal inflammation and smooth muscle hyperresponsiveness. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 17215437	2007
The Toll-interleukin-1 receptor member SIGIRR regulates colonic epithelial homeostasis, inflammation, and tumorigenesis. Immunity\| PubMed ID: 17398123	2007
Toll-like receptor 2 plays a critical role in maintaining mucosal integrity during Citrobacter rodentium-induced colitis. Cellular microbiology\| PubMed ID: 17910742	2008
Modulation of intestinal goblet cell function during infection by an attaching and effacing bacterial pathogen. Infection and immunity\| PubMed ID: 17984203	2008
Role of M-CSF-dependent macrophages in colitis is driven by the nature of the inflammatory stimulus. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 18202111	2008
Flagellin-dependent and -independent inflammatory responses following infection by enteropathogenic Escherichia coli and Citrobacter rodentium. Infection and immunity\| PubMed ID: 18227166	2008
Chronic enteric salmonella infection in mice leads to severe and persistent intestinal fibrosis. Gastroenterology\| PubMed ID: 18325390	2008
A novel secretion pathway of Salmonella enterica acts as an antivirulence modulator during salmonellosis. PLoS pathogens\| PubMed ID: 18389060	2008
Nramp1 expression by dendritic cells modulates inflammatory responses during Salmonella Typhimurium infection. Cellular microbiology\| PubMed ID: 18397382	2008
Nramp1 drives an accelerated inflammatory response during Salmonella-induced colitis in mice. Cellular microbiology\| PubMed ID: 19016783	2009
Intestinal microbiota are transiently altered during Salmonella-induced gastroenteritis. Expert review of gastroenterology & hepatology\| PubMed ID: 19072400	2008
Absence of stearoyl-CoA desaturase-1 does not promote DSS-induced acute colitis. Biochimica et biophysica acta\| PubMed ID: 19695343	2009
Salmonella infection of gallbladder epithelial cells drives local inflammation and injury in a model of acute typhoid fever. The Journal of infectious diseases\| PubMed ID: 19852670	2009
The single IgG IL-1-related receptor controls TLR responses in differentiated human intestinal epithelial cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20130217	2010
Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases. Immunity\| PubMed ID: 20226691	2010
The pathogenic E. coli type III effector EspZ interacts with host CD98 and facilitates host cell prosurvival signalling. Cellular microbiology\| PubMed ID: 20374249	2010
Loss of single immunoglobulin interlukin-1 receptor-related molecule leads to enhanced colonic polyposis in Apc(min) mice. Gastroenterology\| PubMed ID: 20416302	2010
Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa. PLoS pathogens\| PubMed ID: 20485566	2010
Epithelial p38alpha controls immune cell recruitment in the colonic mucosa. PLoS pathogens\| PubMed ID: 20532209	2010
Interleukin-11 reduces TLR4-induced colitis in TLR2-deficient mice and restores intestinal STAT3 signaling. Gastroenterology\| PubMed ID: 20600022	2010
Dissemination of invasive Salmonella via bacterial-induced extrusion of mucosal epithelia. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20876119	2010
Citrobacter rodentium infection induces MyD88-dependent formation of ubiquitinated protein aggregates in the intestinal epithelium. Journal of innate immunity\| PubMed ID: 20962508	2011
Attaching and effacing bacterial effector NleC suppresses epithelial inflammatory responses by inhibiting NF-ÎºB and p38 mitogen-activated protein kinase activation. Infection and immunity\| PubMed ID: 21746856	2011
Innate host responses to enteric bacterial pathogens: a balancing act between resistance and tolerance. Cellular microbiology\| PubMed ID: 22233392	2012
Regulated virulence controls the ability of a pathogen to compete with the gut microbiota. Science (New York, N.Y.)\| PubMed ID: 22582016	2012
MyD88 signaling promotes both mucosal homeostatic and fibrotic responses during Salmonella-induced colitis. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 22679002	2012
Active vitamin D (1,25-dihydroxyvitamin D3) increases host susceptibility to Citrobacter rodentium by suppressing mucosal Th17 responses. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 23019194	2012
Resistin-like Molecule Î± Promotes Pathogenic Th17 Cell Responses and Bacterial-Induced Intestinal Inflammation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23355735	2013