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JoVE Journal
Immunology and Infection

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The Citrobacter rodentium Mouse Model

The Citrobacter rodentium Mouse Model: Studying Pathogen and Host Contributions to Infectious Colitis

Article DOI: 10.3791/50222
February 19th, 2013


Summary February 19th, 2013

Citrobacter rodentium infection provides a valuable model to study enteric bacterial infections as well as host immune responses and colitis in mice. This protocol outlines the measurement of barrier integrity, pathogen load and histological damage allowing for the thorough characterization of pathogen and host contributions to murine infectious colitis.

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