Kai Yang

Department of Orthopedics, Shanghai Jiao Tong University School of Medicine

Affiliated withShanghai Jiao Tong University School of Medicine

Research Area

Biography

The differentiation, maturation and senescence of osteocytes during pathophysiology.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2023

Other Publications

Article	Year
SUMO2 and SUMO3 transcription is differentially regulated by oxidative stress in an Sp1-dependent manner. The Biochemical journal\| PubMed ID: 21291420	2011
The biphasic redox sensing of SENP3 accounts for the HIF-1 transcriptional activity shift by oxidative stress. Acta pharmacologica Sinica\| PubMed ID: 22684029	2012
Role of M3 mAChR in in vivo and in vitro models of LPS-induced inflammatory response. International immunopharmacology\| PubMed ID: 22910223	2012
Targeted inhibition of KCa3.1 channel attenuates airway inflammation and remodeling in allergic asthma. American journal of respiratory cell and molecular biology\| PubMed ID: 23492185	2013
M3 mAChR-mediated IL-8 expression through PKC/NF-κB signaling pathways. Inflammation research : official journal of the European Histamine Research Society ... [et al.]\| PubMed ID: 24522860	2014
De-SUMOylation of FOXC2 by SENP3 promotes the epithelial-mesenchymal transition in gastric cancer cells. Oncotarget\| PubMed ID: 25216525	2014
SoNar, a Highly Responsive NAD+/NADH Sensor, Allows High-Throughput Metabolic Screening of Anti-tumor Agents. Cell metabolism\| PubMed ID: 25955212	2015
Increased EZH2 and decreased osteoblastogenesis during local irradiation-induced bone loss in rats. Scientific reports\| PubMed ID: 27499068	2016
A redox mechanism underlying nucleolar stress sensing by nucleophosmin. Nature communications\| PubMed ID: 27886181	2016
Nicotinamide Adenine Dinucleotide Protects against Spinal Cord Ischemia Reperfusion Injury-Induced Apoptosis by Blocking Autophagy. Oxidative medicine and cellular longevity\| PubMed ID: 28367271	2017
Hydrogen Sulfide Inhibits Autophagic Neuronal Cell Death by Reducing Oxidative Stress in Spinal Cord Ischemia Reperfusion Injury. Oxidative medicine and cellular longevity\| PubMed ID: 28685010	2017
DeSUMOylation of MKK7 kinase by the SUMO2/3 protease SENP3 potentiates lipopolysaccharide-induced inflammatory signaling in macrophages. The Journal of biological chemistry\| PubMed ID: 29352108	2018
SF-deferoxamine, a bone-seeking angiogenic drug, prevents bone loss in estrogen-deficient mice. Bone\| PubMed ID: 30385424	2019
Vascularized 3D printed scaffolds for promoting bone regeneration. Biomaterials\| PubMed ID: 30415019	2019
Nucleolar Stress: hallmarks, sensing mechanism and diseases. Cell stress\| PubMed ID: 31225478	2018
The first two Chinese Myhre syndrome patients with the recurrent SMAD4 pathogenic variants: Functional consequences and clinical diversity. Clinica chimica acta; international journal of clinical chemistry\| PubMed ID: 31654632	2020
SENP3 Suppresses Osteoclastogenesis by De-conjugating SUMO2/3 from IRF8 in Bone Marrow-Derived Monocytes. Cell reports\| PubMed ID: 32049023	2020
The recombinant Newcastle disease virus Anhinga strain expressing human TRAIL exhibit antitumor effects on a glioma nude mice model. Journal of medical virology\| PubMed ID: 32779745	2021
High Mineralization Capacity of IDG-SW3 Cells in 3D Collagen Hydrogel for Bone Healing in Estrogen-Deficient Mice. Frontiers in bioengineering and biotechnology\| PubMed ID: 32984264	2020
Hypoxia and Porphyromonas gingivalis-lipopolysaccharide synergistically induce NLRP3 inflammasome activation in human gingival fibroblasts. International immunopharmacology\| PubMed ID: 33588175	2021
RXR Blocks Nerve Regeneration after Spinal Cord Injury by Targeting p66shc. Oxidative medicine and cellular longevity\| PubMed ID: 33628383	2021
Expert consensus on the clinical application of recombinant adenovirus human p53 for head and neck cancers. International journal of oral science\| PubMed ID: 34785635	2021
α-Asarone Attenuates Osteoclastogenesis and Prevents Against Oestrogen-Deficiency Induced Osteoporosis. Frontiers in pharmacology\| PubMed ID: 35370648	2022
An 8-year clinical experience with diagnosis and treatment of adrenal lesions with calcification. Scientific reports\| PubMed ID: 35414710	2022
Development of an Orally Active Small-Molecule Inhibitor of Receptor Activator of Nuclear Factor-κB Ligand. Journal of medicinal chemistry\| PubMed ID: 35960655	2022
A deep learning approach for anterior cruciate ligament rupture localization on knee MR images. Frontiers in bioengineering and biotechnology\| PubMed ID: 36246358	2022
Diagnostic Value of CT Window Technique for Primary Omentum Infarction. Computational and mathematical methods in medicine\| PubMed ID: 36267314	2022
Application of metabolomics in osteoporosis research. Frontiers in endocrinology\| PubMed ID: 36452325	2022
[Role of SIRTs in cerebral ischemia reperfusion injury and targeted intervention of Chinese medicine]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica\| PubMed ID: 36471954	2022
Treatment of Advanced Kienböck's Disease Using 3D Printing Assisted Autologous Costochondral Transplantation: A Case Report. JBJS case connector\| PubMed ID: 36732040	2022
3D Biomimetic Calcified Cartilaginous Callus that Induces Type H Vessels Formation and Osteoclastogenesis. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 36999832	2023
MAPK8 and CAPN1 as potential biomarkers of intervertebral disc degeneration overlapping immune infiltration, autophagy, and ceRNA. Frontiers in immunology\| PubMed ID: 37325630	2023
Neuropeptide Y-Mediated Gut Microbiota Alterations Aggravate Postmenopausal Osteoporosis. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 37857552	2023
Identification of potential biomarkers for breast cancer based on salivary metabolomics. Frontiers in oncology\| PubMed ID: 41142631	2025