Birgit Schilling

Buck Institute for Age Research

Affiliated withBuck Institute for Age Research Buck Institute for Research on Aging

Research Area

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JoVE Journal Publications

ArticleTotal : 4	Year
Publication title Cited by 13	2009
Publication title Cited by 11	2018
Publication title Cited by 9	2020
Publication title Cited by 6	2020

Other Publications

Article	Year
Characterization of lipooligosaccharides from Haemophilus ducreyi containing polylactosamine repeats. Journal of the American Society for Mass Spectrometry\| PubMed ID: 12056572	2002
Metabolic incorporation of unnatural sialic acids into Haemophilus ducreyi lipooligosaccharides. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12615992	2003
Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12869695	2003
MS2Assign, automated assignment and nomenclature of tandem mass spectra of chemically crosslinked peptides. Journal of the American Society for Mass Spectrometry\| PubMed ID: 12892908	2003
Phosphospecific proteolysis for mapping sites of protein phosphorylation. Nature biotechnology\| PubMed ID: 12923550	2003
Molecular components of a cell death pathway activated by endoplasmic reticulum stress. The Journal of biological chemistry\| PubMed ID: 14561754	2004
Isotopically labeled crosslinking reagents: resolution of mass degeneracy in the identification of crosslinked peptides. Bioorganic & medicinal chemistry letters\| PubMed ID: 14592499	2003
Proteomic and immunochemical characterization of a role for stathmin in adult neurogenesis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 14769823	2004
A novel lectin, DltA, is required for expression of a full serum resistance phenotype in Haemophilus ducreyi. Infection and immunity\| PubMed ID: 15155648	2004
Novel modification of lipid A of Francisella tularensis. Infection and immunity\| PubMed ID: 15322031	2004
Rapid purification and mass spectrometric characterization of mitochondrial NADH dehydrogenase (Complex I) from rodent brain and a dopaminergic neuronal cell line. Molecular & cellular proteomics : MCP\| PubMed ID: 15591592	2005
Mass spectrometric identification of a novel phosphorylation site in subunit NDUFA10 of bovine mitochondrial complex I. FEBS letters\| PubMed ID: 15848193	2005
A pilot proteomic study of amyloid precursor interactors in Alzheimer's disease. Annals of neurology\| PubMed ID: 16049941	2005
Proteomic analysis of succinate dehydrogenase and ubiquinol-cytochrome c reductase (Complex II and III) isolated by immunoprecipitation from bovine and mouse heart mitochondria. Biochimica et biophysica acta\| PubMed ID: 16120479	2006
Huntingtin phosphorylation sites mapped by mass spectrometry. Modulation of cleavage and toxicity. The Journal of biological chemistry\| PubMed ID: 16782707	2006
Novel pathways associated with quinone-induced stress in breast cancer cells. Drug metabolism reviews\| PubMed ID: 17145690	2006
Characterization of lipid A acylation patterns in Francisella tularensis, Francisella novicida, and Francisella philomiragia using multiple-stage mass spectrometry and matrix-assisted laser ... Analytical chemistry\| PubMed ID: 17263332	2007
Small-scale immunopurification of cytochrome c oxidase for a high-throughput multiplexing analysis of enzyme activity and amount. Biotechnology and applied biochemistry\| PubMed ID: 17508937	2007
Mitochondrial oxidative stress causes hyperphosphorylation of tau. PloS one\| PubMed ID: 17579710	2007
Identification of LpxL, a late acyltransferase of Francisella tularensis. Infection and immunity\| PubMed ID: 17724076	2007
Partial acetylation of lysine residues improves intraprotein cross-linking. Analytical chemistry\| PubMed ID: 18201069	2008
A novel serine phosphorylation site detected in the N-terminal domain of estrogen receptor isolated from human breast cancer cells. Journal of the American Society for Mass Spectrometry\| PubMed ID: 18367407	2008
Systematic mapping of posttranslational modifications in human estrogen receptor-alpha with emphasis on novel phosphorylation sites. Molecular & cellular proteomics : MCP\| PubMed ID: 18984578	2009
IDPicker 2.0: Improved protein assembly with high discrimination peptide identification filtering. Journal of proteome research\| PubMed ID: 19522537	2009
Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma. Nature biotechnology\| PubMed ID: 19561596	2009
Preferentially increased nitration of alpha-synuclein at tyrosine-39 in a cellular oxidative model of Parkinson's disease. Analytical chemistry\| PubMed ID: 19697948	2009
The Mycobacterium bovis bacille Calmette-Guerin phagosome proteome. Molecular & cellular proteomics : MCP\| PubMed ID: 19815536	2010
Performance metrics for liquid chromatography-tandem mass spectrometry systems in proteomics analyses. Molecular & cellular proteomics : MCP\| PubMed ID: 19837981	2010
Interlaboratory study characterizing a yeast performance standard for benchmarking LC-MS platform performance. Molecular & cellular proteomics : MCP\| PubMed ID: 19858499	2010
Repeatability and reproducibility in proteomic identifications by liquid chromatography-tandem mass spectrometry. Journal of proteome research\| PubMed ID: 19921851	2010
Targeted quantitation of site-specific cysteine oxidation in endogenous proteins using a differential alkylation and multiple reaction monitoring mass spectrometry approach. Molecular & cellular proteomics : MCP\| PubMed ID: 20233844	2010
A lectin affinity workflow targeting glycosite-specific, cancer-related carbohydrate structures in trypsin-digested human plasma. Analytical biochemistry\| PubMed ID: 20705048	2011
Identification of new modulators and protein alterations in non-apoptotic programmed cell death. Journal of cellular biochemistry\| PubMed ID: 20830744	2010
Confident identification of 3-nitrotyrosine modifications in mass spectral data across multiple mass spectrometry platforms. Journal of proteomics\| PubMed ID: 21514405	2011
ScanRanker: Quality assessment of tandem mass spectra via sequence tagging. Journal of proteome research\| PubMed ID: 21520941	2011
Mass spectrometric identification of novel lysine acetylation sites in huntingtin. Molecular & cellular proteomics : MCP\| PubMed ID: 21685499	2011
A lectin chromatography/mass spectrometry discovery workflow identifies putative biomarkers of aggressive breast cancers. Journal of proteome research\| PubMed ID: 22309216	2012
Platform-independent and label-free quantitation of proteomic data using MS1 extracted ion chromatograms in skyline: application to protein acetylation and phosphorylation. Molecular & cellular proteomics : MCP\| PubMed ID: 22454539	2012
Ubiquitin-specific peptidase 9, X-linked (USP9X) modulates activity of mammalian target of rapamycin (mTOR). The Journal of biological chemistry\| PubMed ID: 22544753	2012
Ligand binding promotes CDK-dependent phosphorylation of ER-alpha on hinge serine 294 but inhibits ligand-independent phosphorylation of serine 305. Molecular cancer research : MCR\| PubMed ID: 22669764	2012
Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23576753	2013
Label-Free Quantitation and Mapping of the ErbB2 Tumor Receptor by Multiple Protease Digestion with Data-Dependent (MS1) and Data-Independent (MS2) Acquisitions. International journal of proteomics\| PubMed ID: 23710360	2013
Site-specific acylation changes in the lipid A of Escherichia coli lpxL mutants grown at high temperatures. Innate immunity\| PubMed ID: 23812252	2014
Phosphoprotein secretome of tumor cells as a source of candidates for breast cancer biomarkers in plasma. Molecular & cellular proteomics : MCP\| PubMed ID: 24505115	2014
Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation. PloS one\| PubMed ID: 24756028	2014
Variation and quantification among a target set of phosphopeptides in human plasma by multiple reaction monitoring and SWATH-MS2 data-independent acquisition. Electrophoresis\| PubMed ID: 24853916	2014
RPL24: a potential therapeutic target whose depletion or acetylation inhibits polysome assembly and cancer cell growth. Oncotarget\| PubMed ID: 24970821	2014
Panorama: a targeted proteomics knowledge base. Journal of proteome research\| PubMed ID: 25102069	2014
Iron promotes protein insolubility and aging in C. elegans. Aging\| PubMed ID: 25554795	2014
Large-Scale Interlaboratory Study to Develop, Analytically Validate and Apply Highly Multiplexed, Quantitative Peptide Assays to Measure Cancer-Relevant Proteins in Plasma. Molecular & cellular proteomics : MCP\| PubMed ID: 25693799	2015
SIRT1 deacetylates RORγt and enhances Th17 cell generation. The Journal of experimental medicine\| PubMed ID: 25918343	2015
Protein acetylation dynamics in response to carbon overflow in Escherichia coli. Molecular microbiology\| PubMed ID: 26264774	2015
Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits. Nature medicine\| PubMed ID: 26390242	2015
Multiplexed, Scheduled, High-Resolution Parallel Reaction Monitoring on a Full Scan QqTOF Instrument with Integrated Data-Dependent and Targeted Mass Spectrometric Workflows. Analytical chemistry\| PubMed ID: 26398777	2015
Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss. Neuron\| PubMed ID: 27041503	2016
Gadd45a Protein Promotes Skeletal Muscle Atrophy by Forming a Complex with the Protein Kinase MEKK4. The Journal of biological chemistry\| PubMed ID: 27358404	2016
Quantification of Lysine Acetylation and Succinylation Stoichiometry in Proteins Using Mass Spectrometric Data-Independent Acquisitions (SWATH). Journal of the American Society for Mass Spectrometry\| PubMed ID: 27590315	2016
Stable nuclear expression of ATP8 and ATP6 genes rescues a mtDNA Complex V null mutant. Nucleic acids research\| PubMed ID: 27596602	2016
Vitamin D Promotes Protein Homeostasis and Longevity via the Stress Response Pathway Genes skn-1, ire-1, and xbp-1. Cell reports\| PubMed ID: 27783938	2016
Generation of High-Quality SWATHAcquisition Data for Label-free Quantitative Proteomics Studies Using TripleTOFMass Spectrometers. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 28188533	2017
Clinical applications of quantitative proteomics using targeted and untargeted data-independent acquisition techniques. Expert review of proteomics\| PubMed ID: 28436239	2017
MSstatsQC: Longitudinal System Suitability Monitoring and Quality Control for Targeted Proteomic Experiments. Molecular & cellular proteomics : MCP\| PubMed ID: 28483925	2017
Identification and characterization of AckA-dependent protein acetylation in Neisseria gonorrhoeae. PloS one\| PubMed ID: 28654654	2017
PIQED: automated identification and quantification of protein modifications from DIA-MS data. Nature methods\| PubMed ID: 28661500	2017
Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry. Nature communications\| PubMed ID: 28827567	2017
Characterization of Inner and Outer Membrane Proteins fromStrains LVS and Schu S4 and Identification of Potential Subunit Vaccine Candidates. mBio\| PubMed ID: 29018123	2017
An acetylatable lysine controls CRP function in E. coli. Molecular microbiology\| PubMed ID: 29105190	2018
Ancient Regulatory Role of Lysine Acetylation in Central Metabolism. mBio\| PubMed ID: 29184018	2017
Protein Turnover in Aging and Longevity. Proteomics\| PubMed ID: 29453826	2018
Removing 4E-BP Enables Synapses to Refine without Postsynaptic Activity. Cell reports\| PubMed ID: 29617653	2018
Simultaneous Quantification of the Acetylome and Succinylome by 'One-Pot' Affinity Enrichment. Proteomics\| PubMed ID: 30035354	2018
Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation. Cell metabolism\| PubMed ID: 30146486	2018
Identifying ubiquitinated proteins and aggregates. Aging\| PubMed ID: 30335616	2018
Identification of Novel Protein Lysine Acetyltransferases in Escherichia coli. mBio\| PubMed ID: 30352934	2018
Temporal dynamics of liver mitochondrial protein acetylation and succinylation and metabolites due to high fat diet and/or excess glucose or fructose. PloS one\| PubMed ID: 30586434	2018
Global Lysine Acetylation in Results from Growth Conditions That Favor Acetate Fermentation. Journal of bacteriology\| PubMed ID: 30782634	2019
JNK modifies neuronal metabolism to promote proteostasis and longevity. Aging cell\| PubMed ID: 30810280	2019
Correction for Christensen et al., "Identification of Novel Protein Lysine Acetyltransferases in Escherichia coli". mBio\| PubMed ID: 30967468	2019
Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation. Molecular cell\| PubMed ID: 31000437	2019
High-Resolution Mass Spectrometry to Identify and Quantify Acetylation Protein Targets. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 31087289	2019
Post-translational Protein Acetylation: An Elegant Mechanism for Bacteria to Dynamically Regulate Metabolic Functions. Frontiers in microbiology\| PubMed ID: 31354686	2019
Accumulation of "Old Proteins" and the Critical Need for MS-based Protein Turnover Measurements in Aging and Longevity. Proteomics\| PubMed ID: 31408259	2019
SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells. Cell reports\| PubMed ID: 31553904	2019
Sirtuin 5 Regulates Proximal Tubule Fatty Acid Oxidation to Protect against AKI. Journal of the American Society of Nephrology : JASN\| PubMed ID: 31575700	2019
Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins. Cell metabolism\| PubMed ID: 31577934	2019
Proteome and Secretome Dynamics of Human Retinal Pigment Epithelium in Response to Reactive Oxygen Species. Scientific reports\| PubMed ID: 31659173	2019
A proteomic atlas of senescence-associated secretomes for aging biomarker development. PLoS biology\| PubMed ID: 31945054	2020
Activating transcription factor 4 (ATF4) promotes skeletal muscle atrophy by forming a heterodimer with the transcriptional regulator C/EBPβ. The Journal of biological chemistry\| PubMed ID: 31953319	2020
Skyline for Small Molecules: A Unifying Software Package for Quantitative Metabolomics. Journal of proteome research\| PubMed ID: 31984744	2020
Abundances of transcripts, proteins, and metabolites in the cell cycle of budding yeast reveal coordinate control of lipid metabolism. Molecular biology of the cell\| PubMed ID: 32129706	2020
The power of proteomics to monitor senescence-associated secretory phenotypes and beyond: toward clinical applications. Expert review of proteomics\| PubMed ID: 32425074	2020
Translational control of one-carbon metabolism underpins ribosomal protein phenotypes in cell division and longevity. eLife\| PubMed ID: 32432546	2020
Cytotrophoblast extracellular vesicles enhance decidual cell secretion of immune modulators via TNF-alpha. Development (Cambridge, England)\| PubMed ID: 32747437	2020