Haoyu Chen

Joint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong

Affiliated withJoint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong The Chinese University of Hong Kong

Research Area

Medicine

Biography

Haoyu Chen has not added Biography.
If you are Haoyu Chen and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2026

Other Publications

Article	Year
KIF21A mutations in two Chinese families with congenital fibrosis of the extraocular muscles (CFEOM). Molecular vision\| PubMed ID: 21042561	2010
Imaging inadvertent Desçemet's membrane break secondary to cataract surgery. Clinical & experimental optometry\| PubMed ID: 21198838	2011
Interactive effects of ATOH7 and RFTN1 in association with adult-onset primary open-angle glaucoma. Investigative ophthalmology & visual science\| PubMed ID: 22222511	2012
Prediction of visual prognosis with spectral-domain optical coherence tomography in outer retinal atrophy secondary to closed globe trauma. Retina (Philadelphia, Pa.)\| PubMed ID: 23508077	2013
Quantitative analysis of retinal layer optical intensities on three-dimensional optical coherence tomography. Investigative ophthalmology & visual science\| PubMed ID: 24045992	2013
Serological association of Chlamydia pneumoniae infection with age-related macular degeneration: a systematic review and meta-analysis. PloS one\| PubMed ID: 25062085	2014
Antagonist of GH-releasing hormone receptors alleviates experimental ocular inflammation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25489106	2014
Quantitative analysis of retinal layers' optical intensities on 3D optical coherence tomography for central retinal artery occlusion. Scientific reports\| PubMed ID: 25784298	2015
Comparison of Retinal Thickness Measurements between the Topcon Algorithm and a Graph-Based Algorithm in Normal and Glaucoma Eyes. PloS one\| PubMed ID: 26042671	2015
Association of Genetic Variants with Polypoidal Choroidal Vasculopathy: A Systematic Review and Updated Meta-analysis. Ophthalmology\| PubMed ID: 26081444	2015
Prediction of spontaneous closure of traumatic macular hole with spectral domain optical coherence tomography. Scientific reports\| PubMed ID: 26196460	2015
Profile and Determinants of Retinal Optical Intensity in Normal Eyes with Spectral Domain Optical Coherence Tomography. PloS one\| PubMed ID: 26863010	2016
Optical Intensities of Different Compartments of Subretinal Fluid in Acute Vogt-Koyanagi-Harada Disease. PloS one\| PubMed ID: 26871896	2016
An automated framework for 3D serous pigment epithelium detachment segmentation in SD-OCT images. Scientific reports\| PubMed ID: 26899236	2016
CORRELATION OF OPTICAL INTENSITY ON OPTICAL COHERENCE TOMOGRAPHY AND VISUAL OUTCOME IN CENTRAL RETINAL ARTERY OCCLUSION. Retina (Philadelphia, Pa.)\| PubMed ID: 26966866	2016
Automatic Three-dimensional Detection of Photoreceptor Ellipsoid Zone Disruption Caused by Trauma in the OCT. Scientific reports\| PubMed ID: 27157473	2016
Risk factors for endophthalmitis requiring evisceration or enucleation. Scientific reports\| PubMed ID: 27302573	2016
HTRA1 promoter variant differentiates polypoidal choroidal vasculopathy from exudative age-related macular degeneration. Scientific reports\| PubMed ID: 27338780	2016
Protective effects of an HTRA1 insertion-deletion variant against age-related macular degeneration in the Chinese populations. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 27841854	2017
Reply. Retina (Philadelphia, Pa.)\| PubMed ID: 28358753	2017
Longitudinal Evaluation of Wound Healing after Penetrating Corneal Injury: Anterior Segment Optical Coherence Tomography Study. Current eye research\| PubMed ID: 28632029	2017
Automated framework for intraretinal cystoid macular edema segmentation in three-dimensional optical coherence tomography images with macular hole. Journal of biomedical optics\| PubMed ID: 28732095	2017
Prevalence and risk factors for diabetic retinopathy in China: a multi-hospital-based cross-sectional study. The British journal of ophthalmology\| PubMed ID: 28855195	2017
Profiling and characterization of microRNAs responding to sodium butyrate treatment in A549 cells. Journal of cellular biochemistry\| PubMed ID: 29231270	2018
Novel Mutations in PRPF31 Causing Retinitis Pigmentosa Identified Using Whole-Exome Sequencing. Investigative ophthalmology & visual science\| PubMed ID: 29260190	2017
Human Periodontal Ligament-Derived Stem Cells Promote Retinal Ganglion Cell Survival and Axon Regeneration After Optic Nerve Injury. Stem cells (Dayton, Ohio)\| PubMed ID: 29476565	2018
Shared-hole graph search with adaptive constraints for 3D optic nerve head optical coherence tomography image segmentation. Biomedical optics express\| PubMed ID: 29541497	2018
Relationship between Optical Intensity on Optical Coherence Tomography and Retinal Ischemia in Branch Retinal Vein Occlusion. Scientific reports\| PubMed ID: 29942024	2018
Effect of optic disc-fovea distance on the normative classifications of macular inner retinal layers as assessed with OCT in healthy subjects. The British journal of ophthalmology\| PubMed ID: 30100556	2019
Intravitreal Injection of Hydrogen Peroxide Induces Acute Retinal Degeneration, Apoptosis, and Oxidative Stress in Mice. Oxidative medicine and cellular longevity\| PubMed ID: 30533172	2018
Whole exome sequencing reveals novel mutations in Chinese patients with autosomal recessive retinitis pigmentosa. Molecular vision\| PubMed ID: 30804660	2019
Whole exome sequencing identifies novel USH2A mutations and confirms Usher syndrome 2 diagnosis in Chinese retinitis pigmentosa patients. Scientific reports\| PubMed ID: 30948794	2019
Performance of Topcon 3D optical coherence tomography-2000 in re-analyzing OCT-1000 raw data. Experimental and therapeutic medicine\| PubMed ID: 31086574	2019
Identification and characterization of a novel promoter variant in placental growth factor for neovascular age-related macular degeneration. Experimental eye research\| PubMed ID: 31377148	2019
Sodium butyrate-activated TRAF6-TXNIP pathway affects A549 cells proliferation and migration. Cancer medicine\| PubMed ID: 31578830	2020
Exome Sequencing Reveals a Heterozygous OAS3 Mutation in a Chinese Family With Juvenile-Onset Open-Angle Glaucoma. Investigative ophthalmology & visual science\| PubMed ID: 31618764	2019
Reliability of foveal avascular zone metrics automatically measured by Cirrus optical coherence tomography angiography in healthy subjects. International ophthalmology\| PubMed ID: 31792852	2020
COL2A1 protective variant reduces sporadic rhegmatogenous retinal detachment severity. Experimental eye research\| PubMed ID: 31899252	2020
ROBO4 deletion ameliorates PAF-mediated skin inflammation via regulating the mRNA translation efficiency of LPCAT1/LPCAT2 and the expression of PAF receptor. International journal of biological sciences\| PubMed ID: 32140075	2020
Retrospective analysis of the possibility of predicting the COVID-19 outbreak from Internet searches and social media data, China, 2020. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin\| PubMed ID: 32183935	2020
Correlation between sub-Tenon's anesthesia and transient amaurosis during ophthalmic surgery. International ophthalmology\| PubMed ID: 32318938	2020
Surgical outcomes of macular hole and epimacular membrane treatment in patients with intraoperative amaurosis under sub-Tenon's anesthesia. The Journal of international medical research\| PubMed ID: 32436475	2020
Different effect of media opacity on automated and manual measurement of foveal avascular zone of optical coherence tomography angiographies. The British journal of ophthalmology\| PubMed ID: 32703785	2021
Hyperreflective Foci Enhancement in a Combined Spatial-Transform Domain for SD-OCT Images. Translational vision science & technology\| PubMed ID: 32714645	2020
Different Effect of Media Opacity on Vessel Density Measured by Different Optical Coherence Tomography Angiography Algorithms. Translational vision science & technology\| PubMed ID: 32855866	2020
Retrospective analysis of the accuracy of predicting the alert level of COVID-19 in 202 countries using Google Trends and machine learning. Journal of global health\| PubMed ID: 33110594	2020
Improved Automated Foveal Avascular Zone Measurement in Cirrus Optical Coherence Tomography Angiography Using the Level Sets Macro. Translational vision science & technology\| PubMed ID: 33240573	2020
Sodium Butyrate Inhibits Neovascularization Partially via TNXIP/VEGFR2 Pathway. Oxidative medicine and cellular longevity\| PubMed ID: 33274003	2020
Fenofibrate Inhibits Subretinal Fibrosis Through Suppressing TGF-β-Smad2/3 signaling and Wnt signaling in Neovascular Age-Related Macular Degeneration. Frontiers in pharmacology\| PubMed ID: 33442383	2020
Whole exome sequencing analysis identifies novel Stargardt disease-related gene mutations in Chinese Stargardt disease and retinitis pigmentosa patients. Eye (London, England)\| PubMed ID: 33846575	2022
Optical Coherence Tomography Angiography Compared with Multimodal Imaging for Diagnosing Neovascular Central Serous Chorioretinopathy. American journal of ophthalmology\| PubMed ID: 34116008	2021
Comparison of Digital Camera Real-Time Display with Conventional Teaching Tube for Slit Lamp Microscopy Teaching. Current eye research\| PubMed ID: 34224279	2022
Agonist of growth hormone-releasing hormone enhances retinal ganglion cell protection induced by macrophages after optic nerve injury. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 34244423	2021
Correlation Between Electroretinogram and Visual Prognosis in Metallic Intraocular Foreign Body Injury. Frontiers in medicine\| PubMed ID: 34249977	2021
Optical coherence tomography biomarkers of photoreceptor degeneration in retinitis pigmentosa. International ophthalmology\| PubMed ID: 34304340	2021
A Multitask Deep-Learning System to Classify Diabetic Macular Edema for Different Optical Coherence Tomography Devices: A Multicenter Analysis. Diabetes care\| PubMed ID: 34315698	2021
Risk Factors for Band Keratopathy in Aphakic Eyes With Silicone Oil Tamponade for Open-Globe Injuries: A Multicenter Case-Control Study. Frontiers in medicine\| PubMed ID: 34368200	2021
A simple eye model for objectively assessing the competency of direct ophthalmoscopy. Eye (London, England)\| PubMed ID: 34373614	2022
Automatic detection of 39 fundus diseases and conditions in retinal photographs using deep neural networks. Nature communications\| PubMed ID: 34376678	2021
Algorithm for Detection and Quantification of Hyperreflective Dots on Optical Coherence Tomography in Diabetic Macular Edema. Frontiers in medicine\| PubMed ID: 34485331	2021
MODIFIED DEVICE FOR SUBRETINAL INJECTION. Retina (Philadelphia, Pa.)\| PubMed ID: 34743131	2022
Optical Coherence Tomography Classification Systems for Diabetic Macular Edema and Their Associations With Visual Outcome and Treatment Responses - An Updated Review. Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)\| PubMed ID: 34923521	2022
Inter-eye Differences in Ocular Biometric Parameters of Concomitant Exotropia. Frontiers in medicine\| PubMed ID: 35059408	2021
COMPARISON OF INTERNAL LIMITING MEMBRANE PEELING WITH THE INVERTED INTERNAL LIMITING MEMBRANE FLAP TECHNIQUE FOR RHEGMATOGENOUS RETINAL DETACHMENT COEXISTING WITH MACULAR HOLE. Retina (Philadelphia, Pa.)\| PubMed ID: 35350048	2022
EFFICIENCY OF LASER PHOTOCOAGULATION ON THE PREVENTION OF RETINAL DETACHMENT IN ACUTE RETINAL NECROSIS: A Systematic Review and Meta-Analysis. Retina (Philadelphia, Pa.)\| PubMed ID: 35576609	2022
Diabetic retinopathy with extensively large area of capillary non-perfusion: characteristics and treatment outcomes. BMC ophthalmology\| PubMed ID: 35787271	2022
Reduction of Laser-Induced Choroidal Neovascularization in Mice With Erythropoietin RNA Interference. Translational vision science & technology\| PubMed ID: 35913417	2022
Mechanisms of Chinese Medicine in Gastroesophageal Reflux Disease Treatment: Data Mining and Systematic Pharmacology Study. Chinese journal of integrative medicine\| PubMed ID: 35997858	2022
Integration of Massive Open Online Course (MOOC) in Ophthalmic Skills Training for Medical Students: Outcomes and Perspectives. Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)\| PubMed ID: 36417679	2022
An interpretable model predicts visual outcomes of no light perception eyes after open globe injury. The British journal of ophthalmology\| PubMed ID: 36596662	2023
Smartphone ophthalmoscope as a tool in teaching direct ophthalmoscopy: a crossover randomized controlled trial. Medical education online\| PubMed ID: 36762913	2023
Response to Letter to the Editor: "Integration of Massive Open Online Course (MOOC) in Ophthalmic Skills Training for Medical Students: Outcomes and Perspectives". Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)\| PubMed ID: 37057751	2023
Multi-Polymorphism Analysis Reveals Joint Effects in Males With Chronic Central Serous Chorioretinopathy. Investigative ophthalmology & visual science\| PubMed ID: 37067365	2023
Changes in the salivary metabolome in patients with chronic erosive gastritis. BMC gastroenterology\| PubMed ID: 37208605	2023
Response to Letter to the Editor: "Integration of Massive Open Online Course (MOOC) in Ophthalmic Skills Training for Medical Students: Outcomes and Perspectives". Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)\| PubMed ID: 38237777	2024
Inter-Individual Topographic Variation of Choroidal Thickness in Healthy Eyes on Swept-Source Optical Coherence Tomography. Translational vision science & technology\| PubMed ID: 38630469	2024
Risk factors for diabetic retinopathy, diabetic macular edema, and sight-threatening diabetic retinopathy. Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)\| PubMed ID: 38750958	2024
Coefficient of spatial variance of choroidal thickness on swept-source optical coherence tomography in healthy eyes. International ophthalmology\| PubMed ID: 38972925	2024
The output of cataract surgery performed by trained non-ophthalmologist physicians in rural areas: study of cataract outcomes and up-take of services report 7. International ophthalmology\| PubMed ID: 38980416	2024
Genome-wide association and multi-omics analyses provide insights into the disease mechanisms of central serous chorioretinopathy. Scientific reports\| PubMed ID: 40097481	2025
Quantifying retinal size and shape distortion in different ultra-widefield imaging systems. BMJ open ophthalmology\| PubMed ID: 40154565	2025
Genome-wide association study identified novel loci and gene-environment interaction for refractive error in children. NPJ genomic medicine\| PubMed ID: 40410244	2025
Generation of multidisease fundus photographs with code-free platform. The British journal of ophthalmology\| PubMed ID: 40664488	2025
Tear lactate improves the evaluation of proliferative diabetic retinopathy in type-2 diabetes patients. Molecular biomedicine\| PubMed ID: 40676452	2025
An artificial intelligence cloud platform for OCT-based retinal anomalies screening system in real clinical environments. NPJ digital medicine\| PubMed ID: 40883412	2025
Persistent global inequality in eye injury burden: a secondary analysis of the 2021 global burden of disease study (1990-2021). BMJ open\| PubMed ID: 40987721	2025
International Consensuses and Guidelines on the Etiology, Diagnosis and Management of Intraocular Foreign Bodies (IOFBs) by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO), t... American journal of ophthalmology\| PubMed ID: 41067482	2026
A deep learning based automatic report generator for retinal optical coherence tomography images. NPJ digital medicine\| PubMed ID: 41115948	2025
Generative AI in medical education: feasibility and educational value of LLM-generated clinical cases with MCQs. BMC medical education\| PubMed ID: 41146115	2025
Direct retrieval of posteriorly dislocated intraocular lenses via limbal air bubble technique. International ophthalmology\| PubMed ID: 41240158	2025
Comparative Performance Evaluation of Large Language Models and Human Teachers in Answering Optometry Questions from Medical Undergraduates. Journal of medical education and curricular development\| PubMed ID: 41487325	2026
In vivo confocal microscopy findings from full corneal epithelial debridement and local corticosteroid for recurrent corneal erosion. Eye (London, England)\| PubMed ID: 41691067	2026
Metabolic vulnerability index and MetaboHealth score as risk factors for age-related macular degeneration in a large-scale prospective cohort. Journal of translational medicine\| PubMed ID: 41703599	2026
Swept-source OCT characterization of dengue retinopathy: Novel grading system and laminar linear retinal hyperreflectivity. Photodiagnosis and photodynamic therapy\| PubMed ID: 41905657	2026
Noninvasive, in vivo, high-resolution investigation of conjunctival vessels in diabetes and hypertension patients. Microvascular research\| PubMed ID: 42103095	2026
PROGNOSTIC FACTORS FOR SECONDARY MACULAR HOLE DEVELOPMENT AFTER SURGERY FOR FOVEA-OFF RHEGMATOGENOUS RETINAL DETACHMENT AND POSTOPERATIVE VISUAL OUTCOMES. Retina (Philadelphia, Pa.)\| PubMed ID: 42153870	2026
Anterior capsule polishing prevents anterior capsule fibrosis after phacovitrectomy without intraocular lens implantation. BMC ophthalmology\| PubMed ID: 42218440	2026
Associations of Multiomics Biological Aging With Diabetic Retinopathy and Life Expectancy. Investigative ophthalmology & visual science\| PubMed ID: 42307181	2026
Shared Genetic Architecture and Multidimensional Modifiable Correlates between Myopia and Retinal-Optic Nerve Diseases. Ophthalmology science\| PubMed ID: 42437114	2026
Construction and Applications of Knowledge Graphs in Ophthalmology. Ophthalmic research\| PubMed ID: 42461904	2026
A novel technique of magnetically guided single-pass limbal extraction for intraocular foreign bodies: Eliminating the need for intraocular instrument relay. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie\| PubMed ID: 42726115	2026