a-novel-high-resolution-vivo-imaging-technique-to-study-dynamic

A Novel High-resolution <em>In vivo</em> Imaging Technique to Study the Dynamic Response of Intracranial Structures to Tumor Growth and Therapeutics

We have successfully integrated previously established Intracranial window (ICW) technology 1-4 with intravital 2-photon confocal microscopy to develop a ...

targeted-muscle-reinnervation-surgical-protocol-for-randomized

Targeted Muscle Reinnervation: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain

Over the past decade, the field of prosthetics has witnessed significant progress, particularly in the development of surgical techniques to enhance the ...

regenerative-peripheral-nerve-interface-surgical-protocol-for

Regenerative Peripheral Nerve Interface: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain

Surgical procedures, including nerve reconstruction and end-organ muscle reinnervation, have become more prominent in the prosthetic field over the past ...

Princess Margaret Hospital

Monash Health

The goal of this study was to compare the diagnostic accuracy of combined computed tomography perfusion (CTP) + computed tomography angiography (CTA), transluminal attenuation gradient by 320-detector row computed tomography (TAG320) + CTA, and CTP + TAG320 + CTA (multidetector computed tomography-integrated protocol [MDCT-IP]) assessment in predicting significant fractional flow reserve (FFR).

Comparison of diagnostic accuracy of combined assessment using adenosine stress computed tomography perfusion + computed tomography angiography with transluminal attenuation gradient + computed tomography angiography against invasive fractional flow reserve.

The systolic forward travelling compression wave (sFCW) and diastolic backward travelling decompression waves (dBEW) predominantly accelerate coronary blood flow. The effect of a coronary stenosis on the intensity of these waves in the distal vessel is unknown. We investigated the relationship between established physiological indices of hyperemic coronary flow and the intensity of the two major accelerative coronary waves identified by Coronary Wave Intensity analysis (CWIA).

Percutaneous Coronary Intervention Enhances Accelerative Wave Intensity in Coronary Arteries.

This study describes the feasibility and accuracy of a novel computed tomography (CT) fractional flow reserve (FFR) technique based on alternative boundary conditions.

Noninvasive CT-Derived FFR Based on Structural and Fluid Analysis: A Comparison With Invasive FFR for Detection of Functionally Significant Stenosis.

Changing epidemiology of candidaemia in Australia.

Knowledge of contemporary epidemiology of candidaemia is essential. We aimed to identify changes since 2004 in incidence, species epidemiology and antifungal susceptibilities of Candida spp. causing candidaemia in Australia.

To assess the impact of elevated heart rate (HR) on the diagnostic accuracy and image quality of second-generation 320-detector computed tomography coronary angiography (320-CTCA).

Impact of heart rate on diagnostic accuracy of second generation 320-detector computed tomography coronary angiography.

The presence and extent of myocardial ischaemia is a major determinant of prognosis and benefit from revascularisation in patients with stable coronary artery disease. Fractional Flow Reserve (FFR) is accepted as the reference standard for invasive assessment of ischaemia. Its ability to detect lesion specific ischaemia makes it a useful test in a wide range of patient and lesion subsets, with FFR guided intervention improving clinical outcomes and reducing health care costs compared to assessment with coronary angiography alone. This article will review the basic principles in FFR, practical tips in FFR guided revascularisation and the role of emerging non-hyperaemic indices of ischaemia.

A Practical Guide for Fractional Flow Reserve Guided Revascularisation.

Surgery has been the standard of care in managing Dupuytren's disease (DD). Recently collagenase of  (CCH) has provided a less invasive alternative. The purpose of the current study is to present the early outcomes of a protocol for CCH involving treatment of multi-cord disease, and large patient cohorts.

Collagenase Management of Multicord Dupuytren's Disease under Intravenous Sedation: A Prospective Cohort Study.

Although many surgical centers perform microsurgery routinely in developed countries, performing microsurgery is challenging in resource-poor developing countries, such as Myanmar. With the establishment of educational training programs and the assistance of volunteer plastic surgical teams, local plastic surgeons can learn the techniques of microsurgery and apply them clinically. The purpose of this study was to establish baseline data and define the challenges of performing microsurgery in Yangon General Hospital, Myanmar. Sixty-four patients underwent reconstruction with free flaps from January 2015 to January 2018. All clinical records of these cases were assessed. The number of free flap reconstructions performed increased from 11 in the first year to 24 in the third year. The anterolateral thigh flap was the most commonly used (42%). The most common sites of reconstruction were mandible and intraoral defects. Total flap survival occurred in 58 of 64 patients (89%). The total salvageable flap rate for revision surgery was 66.6%; the successful revision rate was highest in 2017, with fewer complications. The flap salvage rates increased and the operative duration decreased as clinical experience improved. Establishing a microsurgical center requires a strong multidisciplinary team, clinical experience, continuous learning, sensible clinical application, and effective interdepartmental and intradepartmental cooperation.

Developing Microsurgery through Experience in Yangon General Hospital, Myanmar.

Symptomatic sciatic nerve schwannoma: the challenges of management.

Nocardia is a ubiquitous saprophyte capable of causing human disease. Disease is primarily respiratory or cutaneous, usually acquired via inhalation or inoculation. Under the influence of environmental and host factors, Nocardia incidence and species distribution demonstrate geographical variation.

ArticleTotal : 3	Year
Publication title Cited by 14	2013
Publication title Cited by 5	2024
Publication title Cited by 5	2024

Article	Year
Comparison of diagnostic accuracy of combined assessment using adenosine stress computed tomography perfusion + computed tomography angiography with transluminal attenuation gradient + compu... Journal of the American College of Cardiology\| PubMed ID: 24657696	2014
Percutaneous Coronary Intervention Enhances Accelerative Wave Intensity in Coronary Arteries. PloS one\| PubMed ID: 26658896	2015
Noninvasive CT-Derived FFR Based on Structural and Fluid Analysis: A Comparison With Invasive FFR for Detection of Functionally Significant Stenosis. JACC. Cardiovascular imaging\| PubMed ID: 27771399	2017
Changing epidemiology of candidaemia in Australia. The Journal of antimicrobial chemotherapy\| PubMed ID: 28204502	2017
Changing epidemiology of candidaemia in Australia. The Journal of antimicrobial chemotherapy\| PubMed ID: 28364558	2017
Impact of heart rate on diagnostic accuracy of second generation 320-detector computed tomography coronary angiography. Cardiovascular diagnosis and therapy\| PubMed ID: 28567355	2017
A Practical Guide for Fractional Flow Reserve Guided Revascularisation. Heart, lung & circulation\| PubMed ID: 29191506	2018
Collagenase Management of Multicord Dupuytren's Disease under Intravenous Sedation: A Prospective Cohort Study. Plastic and reconstructive surgery. Global open\| PubMed ID: 30881844	2019
Developing Microsurgery through Experience in Yangon General Hospital, Myanmar. Acta medica Okayama\| PubMed ID: 31649365	2019
Symptomatic sciatic nerve schwannoma: the challenges of management. ANZ journal of surgery\| PubMed ID: 34752680	2022
Nocardia species distribution and antimicrobial susceptibility within Australia. Internal medicine journal\| PubMed ID: 37929813	2023

Michael Leung

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