Jaap A. Joles

Department of Nephrology & Hypertension, University Medical Center Utrecht

Affiliated withUniversity Medical Center Utrecht

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 30	2013

Other Publications

Article	Year
Inducible nitric oxide synthase in renal transplantation. Kidney international\| PubMed ID: 11849440	2002
Proteinuria is preceded by decreased nitric oxide synthesis and prevented by a NO donor in cholesterol-fed rats. Kidney international\| PubMed ID: 11967027	2002
Anti-inflammatory effects of tetrahydrobiopterin on early rejection in renal allografts: modulation of inducible nitric oxide synthase. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 12039851	2002
Visualizing tubular lipid peroxidation in intact renal tissue in hypertensive rats. Journal of the American Society of Nephrology : JASN\| PubMed ID: 12444219	2002
Male gender increases sensitivity to renal injury in response to cholesterol loading. American journal of physiology. Renal physiology\| PubMed ID: 12488246	2003
NO dependency of RBF and autoregulation in the spontaneously hypertensive rat. American journal of physiology. Renal physiology\| PubMed ID: 12631552	2003
Hypoxanthine plus xanthine oxidase causes profound natriuresis without affecting renal blood flow autoregulation. Kidney international\| PubMed ID: 12787413	2003
Bone-marrow-derived cells contribute to glomerular endothelial repair in experimental glomerulonephritis. The American journal of pathology\| PubMed ID: 12875975	2003
Hypoalbuminaemia enhances the renal vasoconstrictor effect of lysophosphatidylcholine. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association\| PubMed ID: 12897085	2003
Temporary losartan or captopril in young SHR induces malignant hypertension despite initial normotension. Kidney international\| PubMed ID: 14717927	2004
Sympathetic hyperactivity in chronic renal failure: a wake-up call. Journal of the American Society of Nephrology : JASN\| PubMed ID: 14978154	2004
Causes and consequences of increased sympathetic activity in renal disease. Hypertension\| PubMed ID: 14981063	2004
Broadly altered gene expression in blood leukocytes in essential hypertension is absent during treatment. Hypertension\| PubMed ID: 15007037	2004
Hypercholesterolemia in rats induces podocyte stress and decreases renal cortical nitric oxide synthesis via an angiotensin II type 1 receptor-sensitive mechanism. Journal of the American Society of Nephrology : JASN\| PubMed ID: 15034097	2004
Perinatal L-arginine and antioxidant supplements reduce adult blood pressure in spontaneously hypertensive rats. Hypertension\| PubMed ID: 15184350	2004
The role of nitric oxide in renal transplantation. Seminars in nephrology\| PubMed ID: 15252777	2004
Programming blood pressure in adult SHR by shifting perinatal balance of NO and reactive oxygen species toward NO: the inverted Barker phenomenon. American journal of physiology. Renal physiology\| PubMed ID: 15547115	2005
The severe cardiorenal syndrome: 'Guyton revisited'. European heart journal\| PubMed ID: 15615794	2005
Nitric oxide-dependent and nitric oxide-independent transcriptional responses to high shear stress in endothelial cells. Hypertension\| PubMed ID: 15699468	2005
Resistance to oxidative stress by chronic infusion of angiotensin II in mouse kidney is not mediated by the AT2 receptor. American journal of physiology. Renal physiology\| PubMed ID: 15727990	2005
To D or not to D: calcitriol and vascular calcification in end-stage renal disease. Journal of hypertension\| PubMed ID: 15834277	2005
Gene expression of energy and protein metabolism in hearts of hypertensive nitric oxide- or GSH-depleted mice. European journal of pharmacology\| PubMed ID: 15878706	2005
Effects of gender on hepatic HMG-CoA reductase, cholesterol 7alpha-hydroxylase, and LDL receptor in hereditary analbuminemia. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 16030068	2005
In mice, proteinuria and renal inflammatory responses to albumin overload are strain-dependent. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association\| PubMed ID: 16326737	2006
Tetrahydrobiopterin, but not L-arginine, decreases NO synthase uncoupling in cells expressing high levels of endothelial NO synthase. Hypertension\| PubMed ID: 16344367	2006
Temporal expression profile and distribution pattern indicate a role of connective tissue growth factor (CTGF/CCN-2) in diabetic nephropathy in mice. American journal of physiology. Renal physiology\| PubMed ID: 16380465	2006
Role of circulating karyocytes in the initiation and progression of atherosclerosis. Hypertension\| PubMed ID: 16520401	2006
Anti-oxidant sensitivity of donor age-related gene expression in cultured fibroblasts. European journal of pharmacology\| PubMed ID: 16797527	2006
Erythropoietin and the cardiorenal syndrome: cellular mechanisms on the cardiorenal connectors. American journal of physiology. Renal physiology\| PubMed ID: 16885153	2006
Low albumin levels increase endothelial NO production and decrease vascular NO sensitivity. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association\| PubMed ID: 16997846	2006
Blood pressure in mutant rats lacking the 5-hydroxytryptamine transporter. Hypertension\| PubMed ID: 17030677	2006
Transcriptome-based identification of pro- and antioxidative gene expression in kidney cortex of nitric oxide-depleted rats. Physiological genomics\| PubMed ID: 17047089	2007
Met-RANTES reduces endothelial progenitor cell homing to activated (glomerular) endothelium in vitro and in vivo. American journal of physiology. Renal physiology\| PubMed ID: 17567937	2007
Protein restriction in lactation confers nephroprotective effects in the male rat and is associated with increased antioxidant expression. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 17581837	2007
Technology insight: Innovative options for end-stage renal disease--from kidney refurbishment to artificial kidney. Nature clinical practice. Nephrology\| PubMed ID: 17895933	2007
Maternal supplementation with citrulline increases renal nitric oxide in young spontaneously hypertensive rats and has long-term antihypertensive effects. Hypertension\| PubMed ID: 17938381	2007
Mixed proximal and distal renal tubular acidosis without aminoaciduria in a mare. Journal of veterinary internal medicine / American College of Veterinary Internal Medicine\| PubMed ID: 17939575	2007
Toll-like receptor 4 mediates maladaptive left ventricular remodeling and impairs cardiac function after myocardial infarction. Circulation research\| PubMed ID: 18007026	2008
Statins and small GTPases: Koch's postulates and chronic kidney disease. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association\| PubMed ID: 18032411	2008
Amelioration of anti-Thy1-glomerulonephritis by PPAR-gamma agonism without increase of endothelial progenitor cell homing. American journal of physiology. Renal physiology\| PubMed ID: 18077601	2008
Detection of basal NO production in rat tissues using iron-dithiocarbamate complexes. Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society\| PubMed ID: 18316042	2008
A perinatal nitric oxide donor increases renal vascular resistance and ameliorates hypertension and glomerular injury in adult fawn-hooded hypertensive rats. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 18417652	2008
CTGF inhibits BMP-7 signaling in diabetic nephropathy. Journal of the American Society of Nephrology : JASN\| PubMed ID: 18632843	2008
Increased expression of SOCS3 in monocytes and SOCS1 in lymphocytes correlates with progressive loss of renal function and cardiovascular risk factors in chronic kidney disease. European journal of pharmacology\| PubMed ID: 18656467	2008
Increased SOCS expression in peripheral blood mononuclear cells of end stage renal disease patients is related to inflammation and dialysis modality. European journal of pharmacology\| PubMed ID: 19041303	2009
Consequences of perinatal treatment with L-arginine and antioxidants for the renal transcriptome in spontaneously hypertensive rats. PflÃ¼gers Archiv : European journal of physiology\| PubMed ID: 19189121	2009
Blood pressure follows the kidney: Perinatal influences on hereditary hypertension. Organogenesis\| PubMed ID: 19279727	2008
Taurine: red bull or red herring? Hypertension\| PubMed ID: 19398654	2009
Is kidney ischemia the central mechanism in parallel activation of the renin and sympathetic system? Journal of hypertension\| PubMed ID: 19444143	2009
Renal venous congestion and renal function in congestive heart failure. Journal of the American College of Cardiology\| PubMed ID: 19833266	2009
Llama heavy-chain antibody fragments efficiently remove toxic shock syndrome toxin 1 from plasma in vitro but not in experimental porcine septic shock. Shock (Augusta, Ga.)\| PubMed ID: 20016410	2010
Renal glutathione S-transferase mu type 1 expression is already reduced in new-born spontaneously hypertensive rats. Journal of hypertension\| PubMed ID: 20160580	2010
Renal proximal tubular dysfunction is a major determinant of urinary connective tissue growth factor excretion. American journal of physiology. Renal physiology\| PubMed ID: 20237235	2010
Perinatal micronutrient supplements ameliorate hypertension and proteinuria in adult fawn-hooded hypertensive rats. American journal of hypertension\| PubMed ID: 20360751	2010
Erythropoietin treatment in patients with combined heart and renal failure: objectives and design of the EPOCARES study. Journal of nephrology\| PubMed ID: 20383871	2010
Reduction of fibrosis-related arrhythmias by chronic renin-angiotensin-aldosterone system inhibitors in an aged mouse model. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 20435847	2010
IFN gamma-dependent SOCS3 expression inhibits IL-6-induced STAT3 phosphorylation and differentially affects IL-6 mediated transcriptional responses in endothelial cells. American journal of physiology. Cell physiology\| PubMed ID: 20484656	2010
Involvement of connective tissue growth factor in human and experimental hypertensive nephrosclerosis. Nephron. Experimental nephrology\| PubMed ID: 20689330	2011
Oxidative stress in obstructive nephropathy. International journal of experimental pathology\| PubMed ID: 20804541	2011
Renal sinus adiposity and hypertension. Hypertension\| PubMed ID: 20837879	2010
The nitric oxide donor molsidomine rescues cardiac function in rats with chronic kidney disease and cardiac dysfunction. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 20852057	2010
Soluble epoxide hydrolase in the generation and maintenance of high blood pressure in spontaneously hypertensive rats. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 21266668	2011
Can exercise prevent preeclampsia? Journal of hypertension\| PubMed ID: 21266859	2010
Loss of endogenous bone morphogenetic protein-6 aggravates renal fibrosis. The American journal of pathology\| PubMed ID: 21356359	2011
Crossing borders: linking environmental and genetic developmental factors. Microcirculation (New York, N.Y. : 1994)\| PubMed ID: 21418373	2011
Perinatal inhibition of NF-kappaB has long-term antihypertensive effects in spontaneously hypertensive rats. Journal of hypertension\| PubMed ID: 21505356	2011
Systemic arterial and venous determinants of renal hemodynamics in congestive heart failure. Heart failure reviews\| PubMed ID: 21553212	2012
Enhanced Angiotensin II type 1 receptor expression in leukocytes of patients with chronic kidney disease. European journal of pharmacology\| PubMed ID: 21640098	2011
Salt sensitivity of blood pressure: developmental and sex-related effects. The American journal of clinical nutrition\| PubMed ID: 21849600	2011
Atorvastatin reduces sympathetic activity in patients with chronic kidney disease. Journal of hypertension\| PubMed ID: 21897294	2011
Expanding the beneficial pleiotropic repertoire of interleukin-10. Journal of hypertension\| PubMed ID: 21989379	2011
Biological and technical considerations regarding the removal of bacteriotoxins in sepsis with emphasis on toxic shock syndrome toxin 1. Shock (Augusta, Ga.)\| PubMed ID: 22129566	2012
Subtotal nephrectomy plus coronary ligation leads to more pronounced damage in both organs than either nephrectomy or coronary ligation. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 22140040	2012
Perinatal exogenous nitric oxide in fawn-hooded hypertensive rats reduces renal ribosomal biogenesis in early life. Frontiers in genetics\| PubMed ID: 22303348	2011
Effect of GFR on plasma N-terminal connective tissue growth factor (CTGF) concentrations. American journal of kidney diseases : the official journal of the National Kidney Foundation\| PubMed ID: 22342213	2012
A novel approach for blood purification: mixed-matrix membranes combining diffusion and adsorption in one step. Acta biomaterialia\| PubMed ID: 22406909	2012
HEALTHY BONE MARROW CELLS REDUCE PROGRESSION OF KIDNEY FAILURE BETTER THAN CKD BONE MARROW CELLS IN RATS WITH ESTABLISHED CHRONIC KIDNEY DISEASE. Cell transplantation\| PubMed ID: 22469231	2012
ACE Inhibition in Anti-Thy1 Glomerulonephritis Limits Proteinuria but Does Not Improve Renal Function and Structural Remodeling. Nephron extra\| PubMed ID: 22479264	2012
Human embryonic mesenchymal stem cell-derived conditioned medium rescues kidney function in rats with established chronic kidney disease. PloS one\| PubMed ID: 22723882	2012
Hypertension: Renal denervation in chronic kidney disease. Nature reviews. Nephrology\| PubMed ID: 22751507	2012
FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair. Nature genetics\| PubMed ID: 22772369	2012
Target organ cross talk in cardiorenal syndrome: animal models. American journal of physiology. Renal physiology\| PubMed ID: 22914779	2012
Short-term erythropoietin treatment does not substantially modulate monocyte transcriptomes of patients with combined heart and renal failure. PloS one\| PubMed ID: 22957013	2012
Early determinants of cardiovascular disease. Best practice & research. Clinical endocrinology & metabolism\| PubMed ID: 22980042	2012
Haemodynamic influences on kidney oxygenation: clinical implications of integrative physiology. Clinical and experimental pharmacology & physiology\| PubMed ID: 23167537	2013
Hemizygous deletion of CTGF/CCN2 does not suffice to prevent fibrosis of the severely injured kidney. Matrix biology : journal of the International Society for Matrix Biology\| PubMed ID: 23199377	2012
Healthy bone marrow cells reduce progression of kidney failure better than CKD bone marrow cells in rats with established chronic kidney disease. Cell transplantation\| PubMed ID: 23231961	2012
The nephron number counts--from womb to tomb. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association\| PubMed ID: 23233524	2013
Bone marrow cell therapy in hypertensive kidney disease: contribution to cardiac fibrosis? Journal of hypertension\| PubMed ID: 23552031	2013
Ischemia and Reactive Oxygen Species in Sympathetic Hyperactivity States: A Vicious Cycle that can be Interrupted by Renal Denervation? Current hypertension reports\| PubMed ID: 23754326	2013
Can exercise partly cure the cardio-renal syndrome? Clinical and experimental pharmacology & physiology\| PubMed ID: 23763456	2013
Comparative physiology and hyperuricemia as a causal factor for hypertension. Obesity (Silver Spring, Md.)\| PubMed ID: 23804295	2013