Sanford I. Bernstein

Biology Department and Heart Institute, San Diego State University

Affiliated withSan Diego State University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 107	2009

Other Publications

Article	Year
The myosin converter domain modulates muscle performance. Nature cell biology\| PubMed ID: 11901423	2002
The converter domain modulates kinetic properties of Drosophila myosin. American journal of physiology. Cell physiology\| PubMed ID: 12477668	2003
Variable N-terminal regions of muscle myosin heavy chain modulate ATPase rate and actin sliding velocity. The Journal of biological chemistry\| PubMed ID: 12606545	2003
Drosophila paramyosin is important for myoblast fusion and essential for myofibril formation. The Journal of cell biology\| PubMed ID: 12642615	2003
UCS proteins: managing the myosin motor. Current biology : CB\| PubMed ID: 12842031	2003
Kinetic analysis of Drosophila muscle myosin isoforms suggests a novel mode of mechanochemical coupling. The Journal of biological chemistry\| PubMed ID: 14506231	2003
Alternative N-terminal regions of Drosophila myosin heavy chain tune muscle kinetics for optimal power output. Biophysical journal\| PubMed ID: 15345559	2004
Passive stiffness of Drosophila IFM myofibrils: a novel, high accuracy measurement method. Journal of muscle research and cell motility\| PubMed ID: 15548865	2004
Drosophila paramyosin is important for myoblast fusion and essential for myofibril formation. The Journal of cell biology\| PubMed ID: 15557126	2004
Paramyosin phosphorylation site disruption affects indirect flight muscle stiffness and power generation in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16020538	2005
An alternative domain near the nucleotide-binding site of Drosophila muscle myosin affects ATPase kinetics. Journal of molecular biology\| PubMed ID: 16154586	2005
An alternative domain near the ATP binding pocket of Drosophila myosin affects muscle fiber kinetics. Biophysical journal\| PubMed ID: 16399836	2006
alphaB-crystallin maintains skeletal muscle myosin enzymatic activity and prevents its aggregation under heat-shock stress. Journal of molecular biology\| PubMed ID: 16546210	2006
Passive stiffness in Drosophila indirect flight muscle reduced by disrupting paramyosin phosphorylation, but not by embryonic myosin S2 hinge substitution. Biophysical journal\| PubMed ID: 17012313	2006
Transcriptional regulation of the Drosophila melanogaster muscle myosin heavy-chain gene. Gene expression patterns : GEP\| PubMed ID: 17194628	2007
Alternative S2 hinge regions of the myosin rod differentially affect muscle function, myofibril dimensions and myosin tail length. Journal of molecular biology\| PubMed ID: 17316684	2007
A variable domain near the ATP-binding site in Drosophila muscle myosin is part of the communication pathway between the nucleotide and actin-binding sites. Journal of molecular biology\| PubMed ID: 17379245	2007
Myosin transducer mutations differentially affect motor function, myofibril structure, and the performance of skeletal and cardiac muscles. Molecular biology of the cell\| PubMed ID: 18045988	2008
Alternative relay domains of Drosophila melanogaster myosin differentially affect ATPase activity, in vitro motility, myofibril structure and muscle function. Journal of molecular biology\| PubMed ID: 18462751	2008
Similarities and differences between frozen-hydrated, rigor acto-S1 complexes of insect flight and chicken skeletal muscles. Journal of molecular biology\| PubMed ID: 18588896	2008
Alternative versions of the myosin relay domain differentially respond to load to influence Drosophila muscle kinetics. Biophysical journal\| PubMed ID: 18805920	2008
The XXXVII European muscle conference: Oxford September 2008. Journal of muscle research and cell motility\| PubMed ID: 19034677	2008
Alternative exon 9-encoded relay domains affect more than one communication pathway in the Drosophila myosin head. Journal of molecular biology\| PubMed ID: 19393244	2009
Alternative S2 hinge regions of the myosin rod affect myofibrillar structure and myosin kinetics. Biophysical journal\| PubMed ID: 19450484	2009
Mutating the converter-relay interface of Drosophila myosin perturbs ATPase activity, actin motility, myofibril stability and flight ability. Journal of molecular biology\| PubMed ID: 20362584	2010
Drosophila UNC-45 prevents heat-induced aggregation of skeletal muscle myosin and facilitates refolding of citrate synthase. Biochemical and biophysical research communications\| PubMed ID: 20403336	2010
Drosophila UNC-45 accumulates in embryonic blastoderm and in muscles, and is essential for muscle myosin stability. Journal of cell science\| PubMed ID: 21285246	2011
X-ray crystal structure of the UCS domain-containing UNC-45 myosin chaperone from Drosophila melanogaster. Structure (London, England : 1993)\| PubMed ID: 21397190	2011
A mighty small heart: the cardiac proteome of adult Drosophila melanogaster. PloS one\| PubMed ID: 21541028	2011
Two Drosophila myosin transducer mutants with distinct cardiomyopathies have divergent ADP and actin affinities. The Journal of biological chemistry\| PubMed ID: 21680742	2011
The UNC-45 chaperone is critical for establishing myosin-based myofibrillar organization and cardiac contractility in the Drosophila heart model. PloS one\| PubMed ID: 21799905	2011
Disrupting the myosin converter-relay interface impairs Drosophila indirect flight muscle performance. Biophysical journal\| PubMed ID: 21889448	2011
Structural basis for myopathic defects engendered by alterations in the myosin rod. Journal of molecular biology\| PubMed ID: 22037585	2011
Transgenic expression and purification of myosin isoforms using the Drosophila melanogaster indirect flight muscle system. Methods (San Diego, Calif.)\| PubMed ID: 22178692	2011
Measuring passive myocardial stiffness in Drosophila melanogaster to investigate diastolic dysfunction. Journal of cellular and molecular medicine\| PubMed ID: 22225769	2012
Alternative Relay and Converter Domains Tune Native Muscle Myosin Isoform Function in Drosophila. Journal of molecular biology\| PubMed ID: 22226837	2011