Susan V. Brooks

Department of Biomedical Engineering, University of Michigan

Affiliated withUniversity of Michigan University of Michigan Medical School

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 15	2013
Publication title Cited by 49	2015

Other Publications

Article	Year
Modular flexibility of dystrophin: implications for gene therapy of Duchenne muscular dystrophy. Nature medicine\| PubMed ID: 11875496	2002
Muscle inflammatory cells after passive stretches, isometric contractions, and lengthening contractions. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 11960936	2002
Functional correction of adult mdx mouse muscle using gutted adenoviral vectors expressing full-length dystrophin. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12271128	2002
Passive stretches protect skeletal muscle of adult and old mice from lengthening contraction-induced injury. The journals of gerontology. Series A, Biological sciences and medical sciences\| PubMed ID: 12865474	2003
Current topics for teaching skeletal muscle physiology. Advances in physiology education\| PubMed ID: 14627615	2003
Susceptibility to sarcomere injury induced by single stretches of maximally activated muscles of mdx mice. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 14715682	2004
Muscles of mice deficient in alpha-sarcoglycan maintain large masses and near control force values throughout the life span. Physiological genomics\| PubMed ID: 15886330	2005
Activation of Akt as a potential mediator of adaptations that reduce muscle injury. Medicine and science in sports and exercise\| PubMed ID: 16775545	2006
Protection from contraction-induced injury provided to skeletal muscles of young and old mice by passive stretch is not due to a decrease in initial mechanical damage. The journals of gerontology. Series A, Biological sciences and medical sciences\| PubMed ID: 16799132	2006
Age-related changes in the structure and function of skeletal muscles. Clinical and experimental pharmacology & physiology\| PubMed ID: 17880359	2007
Direct observation of failing fibers in muscles of dystrophic mice provides mechanistic insight into muscular dystrophy. American journal of physiology. Cell physiology\| PubMed ID: 18171725	2008
Neutrophil accumulation following passive stretches contributes to adaptations that reduce contraction-induced skeletal muscle injury in mice. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 18276901	2008
Force deficits and breakage rates after single lengthening contractions of single fast fibers from unconditioned and conditioned muscles of young and old rats. American journal of physiology. Cell physiology\| PubMed ID: 18508906	2008
Repeated bouts of aerobic exercise lead to reductions in skeletal muscle free radical generation and nuclear factor kappaB activation. The Journal of physiology\| PubMed ID: 18591188	2008
The aging of elite male athletes: age-related changes in performance and skeletal muscle structure and function. Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine\| PubMed ID: 19001883	2008
Conditional knockout of Mn-SOD targeted to type IIB skeletal muscle fibers increases oxidative stress and is sufficient to alter aerobic exercise capacity. American journal of physiology. Cell physiology\| PubMed ID: 19776389	2009
Inhibition of calpain prevents muscle weakness and disruption of sarcomere structure during hindlimb suspension. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 19892928	2010
Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 20040516	2010
The age-related failure of adaptive responses to contractile activity in skeletal muscle is mimicked in young mice by deletion of Cu,Zn superoxide dismutase. Aging cell\| PubMed ID: 20883524	2010
Reactive oxygen species on bone mineral density and mechanics in Cu,Zn superoxide dismutase (Sod1) knockout mice. Biochemical and biophysical research communications\| PubMed ID: 21056548	2010
Decreased specific force and power production of muscle fibers from myostatin-deficient mice are associated with a suppression of protein degradation. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 21565991	2011
Regional stiffening with aging in tibialis anterior tendons of mice occurs independent of changes in collagen fibril morphology. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 21737825	2011
Skeletal muscle weakness due to deficiency of CuZn-superoxide dismutase is associated with loss of functional innervation. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 21900648	2011
Physiological loading of tendons induces scleraxis expression in epitenon fibroblasts. Journal of orthopaedic research : official publication of the Orthopaedic Research Society\| PubMed ID: 21913219	2012
Neb: a zebrafish model of nemaline myopathy due to nebulin mutation. Disease models & mechanisms\| PubMed ID: 22159874	2012
Transforming growth factor-beta induces skeletal muscle atrophy and fibrosis through the induction of atrogin-1 and scleraxis. Muscle & nerve\| PubMed ID: 22190307	2012
Oxidative stress and successful antioxidant treatment in models of RYR1-related myopathy. Brain : a journal of neurology\| PubMed ID: 22418739	2012
Rapamycin slows aging in mice. Aging cell\| PubMed ID: 22587563	2012
Weakness of whole muscles in mice deficient in Cu, Zn superoxide dismutase is not explained by defects at the level of the contractile apparatus. Age (Dordrecht, Netherlands)\| PubMed ID: 22696118	2013
Muscle-specific expression of LARGE restores neuromuscular transmission deficits in dystrophic LARGE(myd) mice. Human molecular genetics\| PubMed ID: 23222475	2013
Age-related changes in structure and extracellular matrix protein expression levels in rat tendons. Age (Dordrecht, Netherlands)\| PubMed ID: 23354684	2013
Eccentric exercise in aging and diseased skeletal muscle: good or bad? Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 23471953	2013
CuZnSOD gene deletion targeted to skeletal muscle leads to loss of contractile force but does not cause muscle atrophy in adult mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 23729587	2013
Targeted inhibition of TGF-Î² results in an initial improvement but long term deficit in force production after contraction-induced skeletal muscle injury. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 23766498	2013
The role of oxidative stress in nervous system aging. PloS one\| PubMed ID: 23844146	2013
Reactive oxygen species generation is not different during isometric and lengthening contractions of mouse muscle. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 23948772	2013
Murine Fig4 is dispensable for muscle development but required for muscle function. Skeletal muscle\| PubMed ID: 24004519	2013
Neuron-specific expression of CuZnSOD prevents the loss of muscle mass and function that occurs in homozygous CuZnSOD-knockout mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 24378874	2014
RNAi-mediated Gene Silencing of Mutant Myotilin Improves Myopathy in LGMD1A Mice. Molecular therapy. Nucleic acids\| PubMed ID: 24781192	2014
Intrinsic stiffness of extracellular matrix increases with age in skeletal muscles of mice. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 24994884	2014
Ten weeks of treadmill running decreases stiffness and increases collagen turnover in tendons of old mice. Journal of orthopaedic research : official publication of the Orthopaedic Research Society\| PubMed ID: 25640809	2015
Age affects the contraction-induced mitochondrial redox response in skeletal muscle. Frontiers in physiology\| PubMed ID: 25698975	2015
Neuron specific reduction in CuZnSOD is not sufficient to initiate a full sarcopenia phenotype. Redox biology\| PubMed ID: 25917273	2015