Helen M. Arthur

Institute of Genetic Medicine, Newcastle University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 83	2013

Other Publications

Article	Year
Endoglin expression in early development is associated with vasculogenesis and angiogenesis. Mechanisms of development\| PubMed ID: 11744382	2002
Mouse model for hereditary hemorrhagic telangiectasia has a generalized vascular abnormality. Circulation\| PubMed ID: 12668501	2003
Vascular endothelial growth factor induces abnormal microvasculature in the endoglin heterozygous mouse brain. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 14747750	2004
Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction. The EMBO journal\| PubMed ID: 15385967	2004
Defective paracrine signalling by TGFbeta in yolk sac vasculature of endoglin mutant mice: a paradigm for hereditary haemorrhagic telangiectasia. Development (Cambridge, England)\| PubMed ID: 15548578	2004
A direct interaction between TGFbeta activated kinase 1 and the TGFbeta type II receptor: implications for TGFbeta signalling and cardiac hypertrophy. Cardiovascular research\| PubMed ID: 16360132	2006
Therapeutic levels of aspirin and salicylate directly inhibit a model of angiogenesis through a Cox-independent mechanism. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 17012253	2006
Endoglin has a crucial role in blood cell-mediated vascular repair. Circulation\| PubMed ID: 17088457	2006
Generation of a floxed allele of the mouse Endoglin gene. Genesis (New York, N.Y. : 2000)\| PubMed ID: 17506087	2007
Extracellular control of TGFbeta signalling in vascular development and disease. Nature reviews. Molecular cell biology\| PubMed ID: 17895899	2007
Circulating endothelial progenitor cells exhibit diurnal variation. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 18296584	2008
Endoglin and activin receptor-like-kinase 1 are co-expressed in the distal vessels of the lung: implications for two familial vascular dysplasias, HHT and PAH. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 19015642	2009
Pathogenesis of arteriovenous malformations in the absence of endoglin. Circulation research\| PubMed ID: 20224041	2010
Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorrhagic telangiectasia. Nature medicine\| PubMed ID: 20364125	2010
The TGFÎ² type II receptor plays a critical role in the endothelial cells during cardiac development. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 20652948	2010
The H9C2 cell line and primary neonatal cardiomyocyte cells show similar hypertrophic responses in vitro. In vitro cellular & developmental biology. Animal\| PubMed ID: 21082279	2011
TGFÎ² signaling and congenital heart disease: Insights from mouse studies. Birth defects research. Part A, Clinical and molecular teratology\| PubMed ID: 21538815	2011
Angiotensin II-induced cardiomyocyte hypertrophy in vitro is TAK1-dependent and Smad2/3-independent. Hypertension research : official journal of the Japanese Society of Hypertension\| PubMed ID: 22072105	2012
Angiogenesis regulation by TGFÎ² signalling: clues from an inherited vascular disease. Biochemical Society transactions\| PubMed ID: 22103504	2011
Non-synonymous variants in the SMAD6 gene predispose to congenital cardiovascular malformation. Human mutation\| PubMed ID: 22275001	2012
Minimal homozygous endothelial deletion of Eng with VEGF stimulation is sufficient to cause cerebrovascular dysplasia in the adult mouse. Cerebrovascular diseases (Basel, Switzerland)\| PubMed ID: 22571958	2012
Endothelial expression of TGFÎ² type II receptor is required to maintain vascular integrity during postnatal development of the central nervous system. PloS one\| PubMed ID: 22745736	2012
Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination. The Journal of experimental medicine\| PubMed ID: 23401487	2013
The tissue-specific RNA binding protein T-STAR controls regional splicing patterns of neurexin pre-mRNAs in the brain. PLoS genetics\| PubMed ID: 23637638	2013