Stella E. Tsirka

Department of Pharmacological Sciences, Stony Brook University

Research Area

Biography

Stella E. Tsirka has not added Biography.
If you are Stella E. Tsirka and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 35	2013

Other Publications

Article	Year
Partial rescue of neural apoptosis in the Lurcher mutant mouse through elimination of tissue plasminogen activator. Development (Cambridge, England)\| PubMed ID: 11934869	2002
Tissue plasminogen activator mediates microglial activation via its finger domain through annexin II. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 11978811	2002
Extracellular proteases and neuronal cell death. Cellular and molecular biology (Noisy-le-Grand, France)\| PubMed ID: 11990450	2002
Tissue plasminogen activator as a modulator of neuronal survival and function. Biochemical Society transactions\| PubMed ID: 12023855	2002
Microglial activation and recruitment, but not proliferation, suffice to mediate neurodegeneration. Cell death and differentiation\| PubMed ID: 12107823	2002
Involvement of tissue plasminogen activator in onset and effector phases of experimental allergic encephalomyelitis. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12486171	2002
Cell type-specific roles for tissue plasminogen activator released by neurons or microglia after excitotoxic injury. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12716930	2003
Protective role of tuftsin fragment 1-3 in an animal model of intracerebral hemorrhage. Annals of neurology\| PubMed ID: 14595655	2003
Modulation of zinc toxicity by tissue plasminogen activator. Molecular and cellular neurosciences\| PubMed ID: 14962749	2004
Increased expression of two phospholipase D isoforms during experimentally induced hippocampal mossy fiber outgrowth. Glia\| PubMed ID: 14999815	2004
Tissue plasminogen activator and glial function. Glia\| PubMed ID: 15494978	2005
Tuftsin fragment 1-3 is beneficial when delivered after the induction of intracerebral hemorrhage. Stroke; a journal of cerebral circulation\| PubMed ID: 15692122	2005
Phospholipase D1-promoted release of tissue plasminogen activator facilitates neurite outgrowth. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15716416	2005
Neuroprotection by inhibition of matrix metalloproteinases in a mouse model of intracerebral haemorrhage. Brain : a journal of neurology\| PubMed ID: 15800021	2005
Fibrin-modifying serine proteases thrombin, tPA, and plasmin in ischemic stroke: a review. Glia\| PubMed ID: 15846799	2005
Contribution of extracellular proteolysis and microglia to intracerebral hemorrhage. Neurocritical care\| PubMed ID: 16159103	2005
PET imaging of glucose metabolism in a mouse model of temporal lobe epilepsy. Synapse (New York, N.Y.)\| PubMed ID: 16320304	2006
Nitric oxide mediates neurodegeneration and breakdown of the blood-brain barrier in tPA-dependent excitotoxic injury in mice. Journal of cell science\| PubMed ID: 16410551	2006
Proteolytic activation of monocyte chemoattractant protein-1 by plasmin underlies excitotoxic neurodegeneration in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17301181	2007
Nitric oxide synthase isoforms undertake unique roles during excitotoxicity. Stroke; a journal of cerebral circulation\| PubMed ID: 17446423	2007
Brain edema after intracerebral hemorrhage: mechanisms, treatment options, management strategies, and operative indications. Neurosurgical focus\| PubMed ID: 17613237	2007
Modulation of microglial/macrophage activation by macrophage inhibitory factor (TKP) or tuftsin (TKPR) attenuates the disease course of experimental autoimmune encephalomyelitis. BMC immunology\| PubMed ID: 17634104	2007
A novel approach for imaging brain-behavior relationships in mice reveals unexpected metabolic patterns during seizures in the absence of tissue plasminogen activator. NeuroImage\| PubMed ID: 17707126	2007
tPA-mediated generation of plasmin is catalyzed by the proteoglycan NG2. Glia\| PubMed ID: 18000864	2008
Tissue-type plasminogen activator as a therapeutic target in stroke. Expert opinion on therapeutic targets\| PubMed ID: 18208365	2008
Endothelial NOS-deficient mice reveal dual roles for nitric oxide during experimental autoimmune encephalomyelitis. Glia\| PubMed ID: 19170181	2009
Decreased serotonin levels associated with behavioral disinhibition in tissue plasminogen activator deficient (tPA-/-) mice. Brain research\| PubMed ID: 20156421	2010
Microglial ablation and lipopolysaccharide preconditioning affects pilocarpine-induced seizures in mice. Neurobiology of disease\| PubMed ID: 20382223	2010
Tissue plasminogen activator alters intracellular sequestration of zinc through interaction with the transporter ZIP4. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20463217	2010
The C terminus of mouse monocyte chemoattractant protein 1 (MCP1) mediates MCP1 dimerization while blocking its chemotactic potency. The Journal of biological chemistry\| PubMed ID: 20682771	2010
Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis. Cell stem cell\| PubMed ID: 20887954	2010
Microglia/macrophages promote glioma progression. Glia\| PubMed ID: 21264953	2011
Truncation of monocyte chemoattractant protein 1 by plasmin promotes blood-brain barrier disruption. Journal of cell science\| PubMed ID: 21486949	2011
Mouse MCP1 C-terminus inhibits human MCP1-induced chemotaxis and BBB compromise. Journal of neurochemistry\| PubMed ID: 21615737	2011
Annexin A2 promotes glioma cell invasion and tumor progression. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21976520	2011
Axonal regrowth after spinal cord injury via chondroitinase and the tissue plasminogen activator (tPA)/plasmin system. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22016526	2011
Animal Models of MS Reveal Multiple Roles of Microglia in Disease Pathogenesis. Neurology research international\| PubMed ID: 22203900	2011
The CCL2-CCR2 system affects the progression and clearance of intracerebral hemorrhage. Glia\| PubMed ID: 22419223	2012
Quantification of particle-induced inflammatory stress response: a novel approach for toxicity testing of earth materials. Geochemical transactions\| PubMed ID: 22513118	2012
Tuftsin promotes an anti-inflammatory switch and attenuates symptoms in experimental autoimmune encephalomyelitis. PloS one\| PubMed ID: 22529957	2012
Microglial inhibitory factor (MIF/TKP) mitigates secondary damage following spinal cord injury. Neurobiology of disease\| PubMed ID: 22613732	2012
p53 opens the mitochondrial permeability transition pore to trigger necrosis. Cell\| PubMed ID: 22726440	2012
Inflammation modulates expression of laminin in the central nervous system following ischemic injury. Journal of neuroinflammation\| PubMed ID: 22759265	2012
Neuroimaging in Animal Seizure Models with (18)FDG-PET. Epilepsy research and treatment\| PubMed ID: 22937232	2011
The annexin A2/S100A10 system in health and disease: emerging paradigms. Journal of biomedicine & biotechnology\| PubMed ID: 23193360	2012
Microglia actively regulate the number of functional synapses. PloS one\| PubMed ID: 23393609	2013
Members of the high mobility group B protein family are dynamically expressed in embryonic neural stem cells. Proteome science\| PubMed ID: 23621913	2013
Inflammatory stress response in A549 cells as a result of exposure to coal: Evidence for the role of pyrite in coal workers' pneumoconiosis pathogenesis. Chemosphere\| PubMed ID: 23895739	2013