Shelley L Berger

Department of Cell and Developmental Biology, University of Pennsylvania

Affiliated withUniversity of Pennsylvania

Research Area

Biography

Shelley L Berger has not added Biography.
If you are Shelley L Berger and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 110	2013

Other Publications

Article	Year
The SANT domain of Ada2 is required for normal acetylation of histones by the yeast SAGA complex. The Journal of biological chemistry\| PubMed ID: 11777910	2002
Histone modifications in transcriptional regulation. Current opinion in genetics & development\| PubMed ID: 11893486	2002
Trans-tail histone modifications: wedge or bridge? Nature structural biology\| PubMed ID: 12145643	2002
SALSA, a variant of yeast SAGA, contains truncated Spt7, which correlates with activated transcription. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12186975	2002
Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins. Molecular and cellular biology\| PubMed ID: 12482968	2003
A novel human Ada2 homologue functions with Gcn5 or Brg1 to coactivate transcription. Molecular and cellular biology\| PubMed ID: 12972612	2003
Structural basis for histone and phosphohistone binding by the GCN5 histone acetyltransferase. Molecular cell\| PubMed ID: 14536085	2003
Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8. Genes & development\| PubMed ID: 14563679	2003
Histone modifications: Now summoning sumoylation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14597707	2003
Temporal and spatial changes in transcription factor binding and histone modifications at the steroidogenic acute regulatory protein (stAR) locus associated with stAR transcription. Molecular endocrinology (Baltimore, Md.)\| PubMed ID: 14726488	2004
Histone modification patterns during gene activation. Methods in enzymology\| PubMed ID: 14979022	2004
H2B ubiquitylation and de-ubiquitylation in gene activation. Novartis Foundation symposium\| PubMed ID: 15171247	2004
Good fences make good neighbors: barrier elements and genomic regulation. Molecular cell\| PubMed ID: 15546609	2004
H2B ubiquitin protease Ubp8 and Sgf11 constitute a discrete functional module within the Saccharomyces cerevisiae SAGA complex. Molecular and cellular biology\| PubMed ID: 15657441	2005
Histone H3 phosphorylation can promote TBP recruitment through distinct promoter-specific mechanisms. The EMBO journal\| PubMed ID: 15719021	2005
Maintenance of low histone ubiquitylation by Ubp10 correlates with telomere-proximal Sir2 association and gene silencing. Molecular cell\| PubMed ID: 15721261	2005
Phosphorylation of histone H4 serine 1 during DNA damage requires casein kinase II in S. cerevisiae. Current biology : CB\| PubMed ID: 15823538	2005
Sumoylation of the yeast Gcn5 protein. Biochemistry\| PubMed ID: 16411780	2006
Structure and dimerization of the kinase domain from yeast Snf1, a member of the Snf1/AMPK protein family. Structure (London, England : 1993)\| PubMed ID: 16531232	2006
Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications. Genes & development\| PubMed ID: 16598039	2006
Trimethylation of histone H3 lysine 4 by Set1 in the lytic infection of human herpes simplex virus 1. Journal of virology\| PubMed ID: 16731913	2006
A feed-forward repression mechanism anchors the Sin3/histone deacetylase and N-CoR/SMRT corepressors on chromatin. Molecular and cellular biology\| PubMed ID: 16809761	2006
Phosphorylation of histone H4 Ser1 regulates sporulation in yeast and is conserved in fly and mouse spermatogenesis. Genes & development\| PubMed ID: 16980586	2006
LKB1 is recruited to the p21/WAF1 promoter by p53 to mediate transcriptional activation. Cancer research\| PubMed ID: 17108107	2006
Repression of p53 activity by Smyd2-mediated methylation. Nature\| PubMed ID: 17108971	2006
In vivo dual cross-linking for identification of indirect DNA-associated proteins by chromatin immunoprecipitation. BioTechniques\| PubMed ID: 17191611	2006
CTCF-dependent chromatin boundary element between the latency-associated transcript and ICP0 promoters in the herpes simplex virus type 1 genome. Journal of virology\| PubMed ID: 17267480	2007
Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature\| PubMed ID: 17314980	2007
The complex language of chromatin regulation during transcription. Nature\| PubMed ID: 17522673	2007
H2B ubiquitylation acts as a barrier to Ctk1 nucleosomal recruitment prior to removal by Ubp8 within a SAGA-related complex. Molecular cell\| PubMed ID: 17643376	2007
p53 is regulated by the lysine demethylase LSD1. Nature\| PubMed ID: 17805299	2007
Histone H3 K4 demethylation during activation and attenuation of GAL1 transcription in Saccharomyces cerevisiae. Molecular and cellular biology\| PubMed ID: 17875926	2007
New nomenclature for chromatin-modifying enzymes. Cell\| PubMed ID: 18022353	2007
The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression. Molecular cell\| PubMed ID: 18206973	2008
14-3-3 interaction with histone H3 involves a dual modification pattern of phosphoacetylation. Molecular and cellular biology\| PubMed ID: 18268010	2008
The emerging field of dynamic lysine methylation of non-histone proteins. Current opinion in genetics & development\| PubMed ID: 18339539	2008
The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression. Genes & development\| PubMed ID: 18832071	2008
Hit and run: transient deubiquitylase activity in a chromatin-remodeling complex. Molecular cell\| PubMed ID: 18922460	2008
The histone variant H3.3 regulates gene expression during lytic infection with herpes simplex virus type 1. Journal of virology\| PubMed ID: 19004946	2009
Out of the jaws of death: PRMT5 steers p53. Nature cell biology\| PubMed ID: 19043433	2008
Protein acetylation microarray reveals that NuA4 controls key metabolic target regulating gluconeogenesis. Cell\| PubMed ID: 19303850	2009
An operational definition of epigenetics. Genes & development\| PubMed ID: 19339683	2009
Genome reprogramming during sporulation. The International journal of developmental biology\| PubMed ID: 19412896	2009
Histone H4 lysine 16 acetylation regulates cellular lifespan. Nature\| PubMed ID: 19516333	2009
Identification and characterization of novel sirtuin inhibitor scaffolds. Bioorganic & medicinal chemistry\| PubMed ID: 19734050	2009
Inactivation of the Sas2 histone acetyltransferase delays senescence driven by telomere dysfunction. The EMBO journal\| PubMed ID: 19875981	2010
G9a and Glp methylate lysine 373 in the tumor suppressor p53. The Journal of biological chemistry\| PubMed ID: 20118233	2010
Chromatin dynamics during herpes simplex virus-1 lytic infection. Biochimica et biophysica acta\| PubMed ID: 20139038	2010
Genome-wide mapping of histone H4 serine-1 phosphorylation during sporulation in Saccharomyces cerevisiae. Nucleic acids research\| PubMed ID: 20375100	2010
Keeping p53 in check: a high-stakes balancing act. Cell\| PubMed ID: 20603009	2010
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. Science (New York, N.Y.)\| PubMed ID: 20647423	2010
Systematic screen reveals new functional dynamics of histones H3 and H4 during gametogenesis. Genes & development\| PubMed ID: 20713519	2010
Genomic comparison of the ants Camponotus floridanus and Harpegnathos saltator. Science (New York, N.Y.)\| PubMed ID: 20798317	2010
Epigenetic drugs can stimulate metastasis through enhanced expression of the pro-metastatic Ezrin gene. PloS one\| PubMed ID: 20856924	2010
Cutting edge: persistently open chromatin at effector gene loci in resting memory CD8+ T cells independent of transcriptional status. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21278341	2011
A genetic and molecular toolbox for analyzing histone ubiquitylation and sumoylation in yeast. Methods (San Diego, Calif.)\| PubMed ID: 21310241	2011
The contribution of epigenetic memory to immunologic memory. Current opinion in genetics & development\| PubMed ID: 21330128	2011
Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress. Genes & development\| PubMed ID: 21576264	2011
Acetylation of yeast AMPK controls intrinsic aging independently of caloric restriction. Cell\| PubMed ID: 21906795	2011
Histone H4 lysine 20 of Saccharomyces cerevisiae is monomethylated and functions in subtelomeric silencing. Biochemistry\| PubMed ID: 21985125	2011
MYST protein acetyltransferase activity requires active site lysine autoacetylation. The EMBO journal\| PubMed ID: 22020126	2012
H2B ubiquitylation is part of chromatin architecture that marks exon-intron structure in budding yeast. BMC genomics\| PubMed ID: 22188810	2011
Transgenerational inheritance of longevity: epigenetic mysteries abound. Cell metabolism\| PubMed ID: 22225870	2012
IDH mutation impairs histone demethylation and results in a block to cell differentiation. Nature\| PubMed ID: 22343901	2012
Gcn5p-dependent acetylation induces degradation of the meiotic transcriptional repressor Ume6p. Molecular biology of the cell\| PubMed ID: 22438583	2012
The linker histone plays a dual role during gametogenesis in Saccharomyces cerevisiae. Molecular and cellular biology\| PubMed ID: 22586276	2012
Genome-wide and caste-specific DNA methylomes of the ants Camponotus floridanus and Harpegnathos saltator. Current biology : CB\| PubMed ID: 22885060	2012
Phylogenetic and transcriptomic analysis of chemosensory receptors in a pair of divergent ant species reveals sex-specific signatures of odor coding. PLoS genetics\| PubMed ID: 22952454	2012
Low-hanging fruit: targeting Brdt in the testes. The EMBO journal\| PubMed ID: 22960636	2012
A chromatin link to caste identity in the carpenter ant Camponotus floridanus. Genome research\| PubMed ID: 23212948	2013
Social insect genomes exhibit dramatic evolution in gene composition and regulation while preserving regulatory features linked to sociality. Genome research\| PubMed ID: 23636946	2013
Genome-wide epigenetics. The Journal of investigative dermatology\| PubMed ID: 23673507	2013
Lysosome-mediated processing of chromatin in senescence. The Journal of cell biology\| PubMed ID: 23816621	2013
Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape. Genes & development\| PubMed ID: 23934658	2013