Douglas K. Graham

Department of Pediatrics, University of Colorado Anschutz Medical Campus

Affiliated withUniversity of Colorado Anschutz Medical Campus

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2013

Other Publications

Article	Year
Molecular genetic analysis of a small bowel primitive neuroectodermal tumor. Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society\| PubMed ID: 11815873	2002
Disseminated nasopharyngeal natural killer cell lymphoblastic lymphoma in a child. Medical and pediatric oncology\| PubMed ID: 12555256	2003
Successful treatment of severe aplastic anemia in children using standardized immunosuppressive therapy with antithymocyte globulin and cyclosporine A. Pediatric blood & cancer\| PubMed ID: 15390303	2004
Ectopic expression of the proto-oncogene Mer in pediatric T-cell acute lymphoblastic leukemia. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 16675557	2006
A soluble form of the Mer receptor tyrosine kinase inhibits macrophage clearance of apoptotic cells and platelet aggregation. Blood\| PubMed ID: 17047157	2007
Precursor natural killer cell leukemia. Pediatric blood & cancer\| PubMed ID: 17417789	2008
Natural killer cell neoplasms. Cancer\| PubMed ID: 18286525	2008
BAC to the future? comparative genomic hybridization and genotyping pediatric leukemia cytogenetic abnormalities. Pediatric blood & cancer\| PubMed ID: 18300321	2008
TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer. Advances in cancer research\| PubMed ID: 18620092	2008
Pediatric developmental therapies: interesting new drugs now in early-stage clinical trials. Current oncology reports\| PubMed ID: 18928662	2008
Tacrolimus as an alternative to cyclosporine in the maintenance phase of immunosuppressive therapy for severe aplastic anemia in children. Pediatric blood & cancer\| PubMed ID: 19148946	2009
Mer tyrosine kinase (MerTK) promotes macrophage survival following exposure to oxidative stress. Journal of leukocyte biology\| PubMed ID: 19386698	2009
Mer receptor tyrosine kinase is a novel therapeutic target in pediatric B-cell acute lymphoblastic leukemia. Blood\| PubMed ID: 19643988	2009
Thymoma in children: report of 2 cases and review of the literature. Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society\| PubMed ID: 20055684	2010
Gray zone lymphomas in pediatric patients. Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society\| PubMed ID: 20331368	2011
Inhibition of Mer and Axl receptor tyrosine kinases in astrocytoma cells leads to increased apoptosis and improved chemosensitivity. Molecular cancer therapeutics\| PubMed ID: 20423999	2010
Taking aim at Mer and Axl receptor tyrosine kinases as novel therapeutic targets in solid tumors. Expert opinion on therapeutic targets\| PubMed ID: 20809868	2010
Targeting paediatric acute lymphoblastic leukaemia: novel therapies currently in development. British journal of haematology\| PubMed ID: 20813012	2010
Constitutive induction of pro-inflammatory and chemotactic cytokines in cystathionine beta-synthase deficient homocystinuria. Molecular genetics and metabolism\| PubMed ID: 21601502	2011
TAM receptors in leukemia: expression, signaling, and therapeutic implications. Critical reviews in oncogenesis\| PubMed ID: 22150307	2011
Prolonged exposure to a Mer ligand in leukemia: Gas6 favors expression of a partial Mer glycoform and reveals a novel role for Mer in the nucleus. PloS one\| PubMed ID: 22363695	2012
Discovery of Novel Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia. ACS medicinal chemistry letters\| PubMed ID: 22662287	2012
Moderate aplastic anemia in children: preliminary outcomes for treatment versus observation from a single-institutional experience. Journal of pediatric hematology/oncology\| PubMed ID: 23128338	2013
Bioluminescence imaging of leukemia cell lines in vitro and in mouse xenografts: effects of monoclonal and polyclonal cell populations on intensity and kinetics of photon emission. Journal of hematology & oncology\| PubMed ID: 23343252	2013
MERTK receptor tyrosine kinase is a therapeutic target in melanoma. The Journal of clinical investigation\| PubMed ID: 23585477	2013
Dual ALK and MYC rearrangements leading to an aggressive variant of anaplastic large cell lymphoma. Journal of pediatric hematology/oncology\| PubMed ID: 23619105	2013
UNC1062, a new and potent Mer inhibitor. European journal of medicinal chemistry\| PubMed ID: 23693152	2013
Molecular Pathways: MERTK Signaling in Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 23833304	2013
Mer receptor tyrosine kinase is a therapeutic target in pre-B-cell acute lymphoblastic leukemia. Blood\| PubMed ID: 23861246	2013
MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis. The Journal of clinical investigation\| PubMed ID: 23867499	2013
UNC569, a novel small molecule Mer inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo. Molecular cancer therapeutics\| PubMed ID: 23997116	2013