Thomas Reiner

Center for Systems Biology, Massachusetts General Hospital

Affiliated withMassachusetts General Hospital Memorial Sloan Kettering Cancer Center Weill Cornell Medical College

Research Area

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JoVE Journal Publications

ArticleTotal : 4	Year
Publication title	2013
Publication title Cited by 7	2015
Publication title	2017
Publication title Cited by 7	2017

Other Publications

Article	Year
Near-infrared fluorescent probe for imaging of pancreatic beta cells. Bioconjugate chemistry\| PubMed ID: 20583828	2010
Bioorthogonal small-molecule ligands for PARP1 imaging in living cells. Chembiochem : a European journal of chemical biology\| PubMed ID: 20967817	2010
High-Yielding, Two-Step (18)F Labeling Strategy for (18)F-PARP1 Inhibitors. ChemMedChem\| PubMed ID: 21207434	2011
Synthesis and in vivo imaging of a 18F-labeled PARP1 inhibitor using a chemically orthogonal scavenger-assisted high-performance method. Angewandte Chemie (International ed. in English)\| PubMed ID: 21328671	2011
High-yielding, two-step 18F labeling strategy for 18F-PARP1 inhibitors. ChemMedChem\| PubMed ID: 21360818	2011
Towards quantitative catalytic lignin depolymerization. Chemistry (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 21472799	2011
In vivo PET imaging of histone deacetylases by 18F-suberoylanilide hydroxamic acid (18F-SAHA). Journal of medicinal chemistry\| PubMed ID: 21721525	2011
Accurate measurement of pancreatic islet beta-cell mass using a second-generation fluorescent exendin-4 analog. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21768367	2011
Bioorthogonal probes for polo-like kinase 1 imaging and quantification. Angewandte Chemie (International ed. in English)\| PubMed ID: 21948435	2011
Nanoparticle-mediated measurement of target-drug binding in cancer cells. ACS nano\| PubMed ID: 21962084	2011
Ubiquitous detection of gram-positive bacteria with bioorthogonal magnetofluorescent nanoparticles. ACS nano\| PubMed ID: 21967150	2011
Specific pathogen detection using bioorthogonal chemistry and diagnostic magnetic resonance. Bioconjugate chemistry\| PubMed ID: 22043803	2011
Imaging therapeutic PARP inhibition in vivo through bioorthogonally developed companion imaging agents. Neoplasia (New York, N.Y.)\| PubMed ID: 22496617	2012
Bioorthogonal imaging of aurora kinase A in live cells. Angewandte Chemie (International ed. in English)\| PubMed ID: 22644700	2012
Microfluidic cell sorter (Î¼FCS) for on-chip capture and analysis of single cells. Advanced healthcare materials\| PubMed ID: 23184773	2012
Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo. Nature communications\| PubMed ID: 23422672	2013
Phenylalanine--a biogenic ligand with flexible Î·6- and Î·6:Îº1-coordination at ruthenium(II) centres. Dalton transactions (Cambridge, England : 2003)\| PubMed ID: 23632736	2013
A Pretargeted PET Imaging Strategy Based on Bioorthogonal Diels-Alder Click Chemistry. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 23708196	2013
Targeting cathepsin E in pancreatic cancer by a small molecule allows in vivo detection. Neoplasia (New York, N.Y.)\| PubMed ID: 23814481	2013
Efficient (18)F-Labeling of Synthetic Exendin-4 Analogues for Imaging Beta Cells. ChemistryOpen\| PubMed ID: 23997998	2012
(18)F-labeled-bioorthogonal liposomes for in vivo targeting. Bioconjugate chemistry\| PubMed ID: 24180480	2013
The inverse electron demand Diels-Alder click reaction in radiochemistry. Journal of labelled compounds & radiopharmaceuticals\| PubMed ID: 24347429	2014
Metal-conjugated affinity labels: a new concept to create enantioselective artificial metalloenzymes. ChemistryOpen\| PubMed ID: 24551533	2013
Effect of small-molecule modification on single-cell pharmacokinetics of PARP inhibitors. Molecular cancer therapeutics\| PubMed ID: 24552776	2014
Efficient acid-catalyzed (18) F/(19) F fluoride exchange of BODIPY dyes. ChemMedChem\| PubMed ID: 24596307	2014
Building Blocks for the Construction of Bioorthogonally Reactive Peptides via Solid-Phase Peptide Synthesis. ChemistryOpen\| PubMed ID: 24808990	2014
In vivo imaging of GLP-1R with a targeted bimodal PET/fluorescence imaging agent. Bioconjugate chemistry\| PubMed ID: 24856928	2014
Synthesis of the first radiolabeled 188Re N-heterocyclic carbene complex and initial studies on its potential use in radiopharmaceutical applications. Journal of labelled compounds & radiopharmaceuticals\| PubMed ID: 24889257	2014
PARPi-FL--a fluorescent PARP1 inhibitor for glioblastoma imaging. Neoplasia (New York, N.Y.)\| PubMed ID: 24970386	2014
A modular labeling strategy for in vivo PET and near-infrared fluorescence imaging of nanoparticle tumor targeting. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 25060196	2014
Cerenkov Luminescence Imaging for Radiation Dose Calculation of a ⁹⁰Y-Labeled Gastrin-Releasing Peptide Receptor Antagonist. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 25840974	2015
Dual-Modality Optical/PET Imaging of PARP1 in Glioblastoma. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging\| PubMed ID: 25895168	2015
PET Imaging of Tumor-Associated Macrophages with 89Zr-Labeled High-Density Lipoprotein Nanoparticles. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 26112022	2015
Development of a clickable bimodal fluorescent/PET probe for in vivo imaging. EJNMMI research\| PubMed ID: 26285667	2015
Optimization of a Pretargeted Strategy for the PET Imaging of Colorectal Carcinoma via the Modulation of Radioligand Pharmacokinetics. Molecular pharmaceutics\| PubMed ID: 26287993	2015
Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation. Science advances\| PubMed ID: 26295063	2015
Radioiodinated PARP1 tracers for glioblastoma imaging. EJNMMI research\| PubMed ID: 26337803	2015
(18)F-Based Pretargeted PET Imaging Based on Bioorthogonal Diels-Alder Click Chemistry. Bioconjugate chemistry\| PubMed ID: 26479967	2016
Non-invasive PET Imaging of PARP1 Expression in Glioblastoma Models. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging\| PubMed ID: 26493053	2016
Optical Imaging of PARP1 in Response to Radiation in Oral Squamous Cell Carcinoma. PloS one\| PubMed ID: 26808835	2016
Detection and delineation of oral cancer with a PARP1 targeted optical imaging agent. Scientific reports\| PubMed ID: 26900125	2016
In Vivo PET Imaging of HDL in Multiple Atherosclerosis Models. JACC. Cardiovascular imaging\| PubMed ID: 27236528	2016
Nanoreporter PET predicts the efficacy of anti-cancer nanotherapy. Nature communications\| PubMed ID: 27319780	2016
Pretargeted PET Imaging Using a Site-Specifically Labeled Immunoconjugate. Bioconjugate chemistry\| PubMed ID: 27356886	2016
Near-Infrared Intraoperative Chemiluminescence Imaging. ChemMedChem\| PubMed ID: 27471800	2016
Immune cell screening of a nanoparticle library improves atherosclerosis therapy. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 27791119	2016
Imaging-guided revival of nanomedicine? Nanomedicine (London, England)\| PubMed ID: 27876441	2017
A Pretargeted Approach for the Multimodal PET/NIRF Imaging of Colorectal Cancer. Theranostics\| PubMed ID: 27924162	2016
Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease. Nature communications\| PubMed ID: 28091604	2017
Biomarker based PET Imaging of Diffuse Intrinsic Pontine Glioma in Mouse Models. Cancer research\| PubMed ID: 28108511	2017
Evaluation of [(18)F]-ATRi as PET tracer for in vivo imaging of ATR in mouse models of brain cancer. Nuclear medicine and biology\| PubMed ID: 28157626	2017
Development of a New Folate-Derived Ga-68-Based PET Imaging Agent. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging\| PubMed ID: 28194631	2017