Carl G. Figdor

Department of Tumor Immunology, Radboud university medical center

Affiliated withRadboud university medical center Radboudumc Radboud University

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 21	2013
Publication title Cited by 7	2023

Other Publications

Article	Year
Regulation of LFA-1 Expression by CD34 Positive Cells and Inducible Growth Factor Production by Stroma Enable Formation of Bone Marrow Compartments; Subject Heading. Hematology (Amsterdam, Netherlands)\| PubMed ID: 11399626	2000
Identification of different binding sites in the dendritic cell-specific receptor DC-SIGN for intercellular adhesion molecule 3 and HIV-1. The Journal of biological chemistry\| PubMed ID: 11799126	2002
The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 11859097	2002
C-type lectin receptors on dendritic cells and Langerhans cells. Nature reviews. Immunology\| PubMed ID: 11910898	2002
Enhancement of G-CSF-induced stem cell mobilization by antibodies against the beta 2 integrins LFA-1 and Mac-1. Blood\| PubMed ID: 12070044	2002
Renal cell carcinoma-associated antigen G250 encodes a naturally processed epitope presented by human leukocyte antigen-DR molecules to CD4(+) T lymphocytes. International journal of cancer. Journal international du cancer\| PubMed ID: 12115527	2002
The small GTPase Rap1 is required for Mn(2+)- and antibody-induced LFA-1- and VLA-4-mediated cell adhesion. The Journal of biological chemistry\| PubMed ID: 12171996	2002
Phenotypical and functional characterization of clinical grade dendritic cells. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 12218781	2002
Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state. Cancer research\| PubMed ID: 12517769	2003
Expression of the dendritic cell-associated C-type lectin DC-SIGN by inflammatory matrix metalloproteinase-producing macrophages in rheumatoid arthritis synovium and interaction with interce... Arthritis and rheumatism\| PubMed ID: 12571844	2003
Peptide fine specificity of anti-glycoprotein 100 CTL is preserved following transfer of engineered TCR alpha beta genes into primary human T lymphocytes. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12574392	2003
The C-type lectin DC-SIGN (CD209) is an antigen-uptake receptor for Candida albicans on dendritic cells. European journal of immunology\| PubMed ID: 12645952	2003
The heme-heme oxygenase system: a molecular switch in wound healing. Blood\| PubMed ID: 12649161	2003
Different faces of the heme-heme oxygenase system in inflammation. Pharmacological reviews\| PubMed ID: 12869663	2003
Analysis of dendritic cell trafficking using EGFP-transgenic mice. Immunology letters\| PubMed ID: 12946860	2003
Ceramic hydroxyapatite coating on titanium implants drives selective bone marrow stromal cell adhesion. Clinical oral implants research\| PubMed ID: 12969360	2003
An automated multi well cell track system to study leukocyte migration. Journal of immunological methods\| PubMed ID: 12972190	2003
Dual function of C-type lectin-like receptors in the immune system. Current opinion in cell biology\| PubMed ID: 14519388	2003
Maturation of dendritic cells is a prerequisite for inducing immune responses in advanced melanoma patients. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 14613986	2003
Presence and localization of T-cell subsets in relation to melanocyte differentiation antigen expression and tumour regression as assessed by immunohistochemistry and molecular analysis of m... The Journal of pathology\| PubMed ID: 14694523	2004
Microdomains of the C-type lectin DC-SIGN are portals for virus entry into dendritic cells. The Journal of cell biology\| PubMed ID: 14709546	2004
Dendritic cell immunotherapy: mapping the way. Nature medicine\| PubMed ID: 15122249	2004
Differentiating stem cells mask their origins. Stem cells (Dayton, Ohio)\| PubMed ID: 15153601	2004
Cytoskeletal restraints regulate homotypic ALCAM-mediated adhesion through PKCalpha independently of Rho-like GTPases. Journal of cell science\| PubMed ID: 15169840	2004
In situ tumor ablation creates an antigen source for the generation of antitumor immunity. Cancer research\| PubMed ID: 15173017	2004
Phenotypical and functional characterization of clinical-grade dendritic cells. Methods in molecular medicine\| PubMed ID: 15585917	2005
The dendritic cell-derived protein DC-STAMP is highly conserved and localizes to the endoplasmic reticulum. Journal of leukocyte biology\| PubMed ID: 15601667	2005
Novel monoclonal antibodies detect elevated levels of the chemokine CCL18/DC-CK1 in serum and body fluids in pathological conditions. Journal of leukocyte biology\| PubMed ID: 15713699	2005
How C-type lectins detect pathogens. Cellular microbiology\| PubMed ID: 15760448	2005
Migration of dendritic cell based cancer vaccines: in vivo veritas? Current opinion in immunology\| PubMed ID: 15766677	2005
"Sweet talk": closing in on C type lectin signaling. Immunity\| PubMed ID: 15845444	2005
Effective induction of naive and recall T-cell responses by targeting antigen to human dendritic cells via a humanized anti-DC-SIGN antibody. Blood\| PubMed ID: 15878980	2005
Elevated CXCL16 expression by synovial macrophages recruits memory T cells into rheumatoid joints. Arthritis and rheumatism\| PubMed ID: 15880344	2005
Levels of complexity in pathogen recognition by C-type lectins. Current opinion in immunology\| PubMed ID: 15950451	2005
Immunomonitoring tumor-specific T cells in delayed-type hypersensitivity skin biopsies after dendritic cell vaccination correlates with clinical outcome. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 16110035	2005
Dendritic cells: tools and targets for antitumor vaccination. Expert review of vaccines\| PubMed ID: 16221071	2005
Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy. Nature biotechnology\| PubMed ID: 16258544	2005
Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation induced by dendritic cells. Blood\| PubMed ID: 16352806	2006
TRPM7, a novel regulator of actomyosin contractility and cell adhesion. The EMBO journal\| PubMed ID: 16407977	2006
Development of 111In-labeled tumor-associated antigen peptides for monitoring dendritic-cell-based vaccination. Nuclear medicine and biology\| PubMed ID: 16720236	2006
Plasmacytoid dendritic cells of melanoma patients present exogenous proteins to CD4+ T cells after Fc gamma RII-mediated uptake. The Journal of experimental medicine\| PubMed ID: 16785312	2006
A critical role for prostaglandin E2 in podosome dissolution and induction of high-speed migration during dendritic cell maturation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16849464	2006
Synergy between in situ cryoablation and TLR9 stimulation results in a highly effective in vivo dendritic cell vaccine. Cancer research\| PubMed ID: 16849578	2006
Organization of the integrin LFA-1 in nanoclusters regulates its activity. Molecular biology of the cell\| PubMed ID: 16855029	2006
C-type lectins on dendritic cells and their interaction with pathogen-derived and endogenous glycoconjugates. Current protein & peptide science\| PubMed ID: 16918443	2006
Targeting antigens to dendritic cells in vivo. Immunobiology\| PubMed ID: 16920498	2006
Cancer-germline gene expression in pediatric solid tumors using quantitative real-time PCR. International journal of cancer. Journal international du cancer\| PubMed ID: 17019710	2007
Relevance of DC-SIGN in DC-induced T cell proliferation. Journal of leukocyte biology\| PubMed ID: 17135574	2007
Sensitivity of magnetic resonance imaging of dendritic cells for in vivo tracking of cellular cancer vaccines. International journal of cancer. Journal international du cancer\| PubMed ID: 17163419	2007
Binding of the adhesion and pathogen receptor DC-SIGN by monocytes is regulated by the density of Lewis X molecules. Molecular immunology\| PubMed ID: 17175026	2007
Dectin-1 interaction with tetraspanin CD37 inhibits IL-6 production. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17182550	2007
Myosin II and mechanotransduction: a balancing act. Trends in cell biology\| PubMed ID: 17320396	2007
Ligand-conjugated quantum dots monitor antigen uptake and processing by dendritic cells. Nano letters\| PubMed ID: 17388641	2007
Phenotypic and functional characterization of mature dendritic cells from pediatric cancer patients. Pediatric blood & cancer\| PubMed ID: 17486645	2007
Nanoscale organization of the pathogen receptor DC-SIGN mapped by single-molecule high-resolution fluorescence microscopy. Chemphyschem : a European journal of chemical physics and physical chemistry\| PubMed ID: 17577901	2007
Dendritic-cell immunotherapy: from ex vivo loading to in vivo targeting. Nature reviews. Immunology\| PubMed ID: 17853902	2007
In vivo targeting of DC-SIGN-positive antigen-presenting cells in a nonhuman primate model. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 17893563	2007
Distinct kinetic and mechanical properties govern ALCAM-mediated interactions as shown by single-molecule force spectroscopy. Journal of cell science\| PubMed ID: 17971418	2007
Targeting DCIR on human plasmacytoid dendritic cells results in antigen presentation and inhibits IFN-alpha production. Blood\| PubMed ID: 18258799	2008
Monocyte cell surface glycosaminoglycans positively modulate IL-4-induced differentiation toward dendritic cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18322173	2008
Maturation of monocyte-derived dendritic cells with Toll-like receptor 3 and 7/8 ligands combined with prostaglandin E2 results in high interleukin-12 production and cell migration. Cancer immunology, immunotherapy : CII\| PubMed ID: 18322684	2008
PGE2-mediated podosome loss in dendritic cells is dependent on actomyosin contraction downstream of the RhoA-Rho-kinase axis. Journal of cell science\| PubMed ID: 18334555	2008
Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7. PloS one\| PubMed ID: 18365021	2008
Interaction of acute lymphopblastic leukemia cells with C-type lectins DC-SIGN and L-SIGN. Experimental hematology\| PubMed ID: 18375037	2008
Human and murine model cell lines for dendritic cell biology evaluated. Immunology letters\| PubMed ID: 18384885	2008
Vaccine-specific local T cell reactivity in immunotherapy-associated vitiligo in melanoma patients. Cancer immunology, immunotherapy : CII\| PubMed ID: 18392619	2009
TRPM7 regulates myosin IIA filament stability and protein localization by heavy chain phosphorylation. Journal of molecular biology\| PubMed ID: 18394644	2008
Selective cancer-germline gene expression in pediatric brain tumors. Journal of neuro-oncology\| PubMed ID: 18398575	2008
Dendritic cell interaction with Candida albicans critically depends on N-linked mannan. The Journal of biological chemistry\| PubMed ID: 18482990	2008
No advantage of cell-penetrating peptides over receptor-specific antibodies in targeting antigen to human dendritic cells for cross-presentation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18490772	2008
Maximizing dendritic cell migration in cancer immunotherapy. Expert opinion on biological therapy\| PubMed ID: 18549318	2008
In vivo colocalization of antigen and CpG [corrected] within dendritic cells is associated with the efficacy of cancer immunotherapy. Cancer research\| PubMed ID: 18593941	2008
The alpha-kinases TRPM6 and TRPM7, but not eEF-2 kinase, phosphorylate the assembly domain of myosin IIA, IIB and IIC. FEBS letters\| PubMed ID: 18675813	2008
Activation of human plasmacytoid dendritic cells by TLR9 impairs Fc gammaRII-mediated uptake of immune complexes and presentation by MHC class II. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18832675	2008
Mesenchymal stromal cells: tissue engineers and immune response modulators. Archivum immunologiae et therapiae experimentalis\| PubMed ID: 18836860	2008
Polyinosinic polycytidylic acid prevents efficient antigen expression after mRNA electroporation of clinical grade dendritic cells. Cancer immunology, immunotherapy : CII\| PubMed ID: 19018531	2009
DCIR is endocytosed into human dendritic cells and inhibits TLR8-mediated cytokine production. Journal of leukocyte biology\| PubMed ID: 19028959	2009
In vivo recruitment of hematopoietic cells using stromal cell-derived factor 1 alpha-loaded heparinized three-dimensional collagen scaffolds. Tissue engineering. Part A\| PubMed ID: 19108679	2009
The tetraspanin protein CD37 regulates IgA responses and anti-fungal immunity. PLoS pathogens\| PubMed ID: 19282981	2009
Limited amounts of dendritic cells migrate into the T-cell area of lymph nodes but have high immune activating potential in melanoma patients. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19318472	2009
In situ expression of tumor antigens by messenger RNA-electroporated dendritic cells in lymph nodes of melanoma patients. Cancer research\| PubMed ID: 19318559	2009
Dynamic re-organization of individual adhesion nanoclusters in living cells by ligand-patterned surfaces. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 19367602	2009
The C-type lectin DC-SIGN internalizes soluble antigens and HIV-1 virions via a clathrin-dependent mechanism. European journal of immunology\| PubMed ID: 19585517	2009
Functional differences between mesenchymal stem cell populations are reflected by their transcriptome. Stem cells and development\| PubMed ID: 19788395	2010
Hotspots of GPI-anchored proteins and integrin nanoclusters function as nucleation sites for cell adhesion. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19850864	2009
The role of tetraspanins in the pathogenesis of infectious diseases. Microbes and infection / Institut Pasteur\| PubMed ID: 19896556	2010
Mesenchymal stem cells respond to TNF but do not produce TNF. Journal of leukocyte biology\| PubMed ID: 19897767	2010
Cord blood mesenchymal stem cells propel human dendritic cells to an intermediate maturation state and boost interleukin-12 production by mature dendritic cells. Immunology\| PubMed ID: 19930046	2009
Route of administration of the TLR9 agonist CpG critically determines the efficacy of cancer immunotherapy in mice. PloS one\| PubMed ID: 20020049	2009
Fungal pattern-recognition receptors and tetraspanins: partners on antigen-presenting cells. Trends in immunology\| PubMed ID: 20036798	2010
TLR4-mediated podosome loss discriminates gram-negative from gram-positive bacteria in their capacity to induce dendritic cell migration and maturation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20038642	2010
Dominant processes during human dendritic cell maturation revealed by integration of proteome and transcriptome at the pathway level. Journal of proteome research\| PubMed ID: 20131907	2010
Ovarian cancer creates a suppressive microenvironment to escape immune elimination. Gynecologic oncology\| PubMed ID: 20144842	2010
Hematopoietic stem cells are coordinated by the molecular cues of the endosteal niche. Stem cells and development\| PubMed ID: 20148648	2010
Targeted PLGA nano- but not microparticles specifically deliver antigen to human dendritic cells via DC-SIGN in vitro. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 20156497	2010
Consolidative dendritic cell-based immunotherapy elicits cytotoxicity against malignant mesothelioma. American journal of respiratory and critical care medicine\| PubMed ID: 20167848	2010
Dendritic cell subsets digested: RNA sensing makes the difference! Immunity\| PubMed ID: 20189479	2010
Toll-like receptor expression and function in human dendritic cell subsets: implications for dendritic cell-based anti-cancer immunotherapy. Cancer immunology, immunotherapy : CII\| PubMed ID: 20204387	2010
Molecular friction as a tool to identify functionalized alkanethiols. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 20225883	2010
Human plasmacytoid dendritic cells phagocytose, process, and present exogenous particulate antigen. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20304825	2010
The tetraspanin CD37 protects against glomerular IgA deposition and renal pathology. The American journal of pathology\| PubMed ID: 20348240	2010
Commonly used prophylactic vaccines as an alternative for synthetically produced TLR ligands to mature monocyte-derived dendritic cells. Blood\| PubMed ID: 20424184	2010
(19)F MRI for quantitative in vivo cell tracking. Trends in biotechnology\| PubMed ID: 20427096	2010
Customizable, multi-functional fluorocarbon nanoparticles for quantitative in vivo imaging using 19F MRI and optical imaging. Biomaterials\| PubMed ID: 20566214	2010
Dendritic cell vaccination in combination with anti-CD25 monoclonal antibody treatment: a phase I/II study in metastatic melanoma patients. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 20736326	2010
The lymphoid chemokine CCL21 triggers LFA-1 adhesive properties on human dendritic cells. Immunology and cell biology\| PubMed ID: 20805842	2011
A novel (19)F agent for detection and quantification of human dendritic cells using magnetic resonance imaging. International journal of cancer. Journal international du cancer\| PubMed ID: 20839261	2011
Wild-type and modified gp100 peptide-pulsed dendritic cell vaccination of advanced melanoma patients can lead to long-term clinical responses independent of the peptide used. Cancer immunology, immunotherapy : CII\| PubMed ID: 21069321	2011
DC-ATLAS: a systems biology resource to dissect receptor specific signal transduction in dendritic cells. Immunome research\| PubMed ID: 21092113	2010
Immunogenicity of dendritic cells pulsed with CEA peptide or transfected with CEA mRNA for vaccination of colorectal cancer patients. Anticancer research\| PubMed ID: 21187495	2010
IL-4 and IL-13 alter plasmacytoid dendritic cell responsiveness to CpG DNA and herpes simplex virus-1. The Journal of investigative dermatology\| PubMed ID: 21191414	2011
Prophylactic vaccines mimic synthetic CpG oligonucleotides in their ability to modulate immune responses. Molecular immunology\| PubMed ID: 21257206	2011
Targeted antigen delivery and activation of dendritic cells in vivo: steps towards cost effective vaccines. Seminars in immunology\| PubMed ID: 21269839	2011
Eradicating cancer cells: struggle with a chameleon. Oncotarget\| PubMed ID: 21378413	2011
Multimodal imaging of nanovaccine carriers targeted to human dendritic cells. Molecular pharmaceutics\| PubMed ID: 21381651	2011
DEC-205 mediates antigen uptake and presentation by both resting and activated human plasmacytoid dendritic cells. European journal of immunology\| PubMed ID: 21413003	2011
Cytokine analysis as a tool to understand tumour-host interaction in ovarian cancer. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 21514148	2011
Infection of dendritic cells with herpes simplex virus type 1 induces rapid degradation of CYTIP, thereby modulating adhesion and migration. Blood\| PubMed ID: 21562043	2011
Antigen localization controls T cell-mediated tumor immunity. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21705625	2011
The influence of PEG chain length and targeting moiety on antibody-mediated delivery of nanoparticle vaccines to human dendritic cells. Biomaterials\| PubMed ID: 21724247	2011
Platinum-based drugs disrupt STAT6-mediated suppression of immune responses against cancer in humans and mice. The Journal of clinical investigation\| PubMed ID: 21765211	2011
Route of administration modulates the induction of dendritic cell vaccine-induced antigen-specific T cells in advanced melanoma patients. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 21771874	2011
Immune adjuvant efficacy of CpG oligonucleotide in cancer treatment is founded specifically upon TLR9 function in plasmacytoid dendritic cells. Cancer research\| PubMed ID: 21788345	2011
Targeting DC-SIGN via its neck region leads to prolonged antigen residence in early endosomes, delayed lysosomal degradation, and cross-presentation. Blood\| PubMed ID: 21860028	2011
Cytokine profiles in cyst fluids from ovarian tumors reflect immunosuppressive state of the tumor. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society\| PubMed ID: 21946293	2011
Targeted delivery of TLR ligands to human and mouse dendritic cells strongly enhances adjuvanticity. Blood\| PubMed ID: 21967977	2011
Early identification of antigen-specific immune responses in vivo by [18F]-labeled 3'-fluoro-3'-deoxy-thymidine ([18F]FLT) PET imaging. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22025695	2011
Interlaboratory round robin on cantilever calibration for AFM force spectroscopy. Ultramicroscopy\| PubMed ID: 22094372	2011
Unraveling the human dendritic cell phagosome proteome by organellar enrichment ranking. Journal of proteomics\| PubMed ID: 22146474	2012
The chemotherapeutic drug oxaliplatin differentially affects blood DC function dependent on environmental cues. Cancer immunology, immunotherapy : CII\| PubMed ID: 22193989	2012
Geometry sensing by dendritic cells dictates spatial organization and PGE(2)-induced dissolution of podosomes. Cellular and molecular life sciences : CMLS\| PubMed ID: 22204022	2012
Regulatory T cells in melanoma: the final hurdle towards effective immunotherapy? The lancet oncology\| PubMed ID: 22225723	2012
The C-type lectin receptor CLEC9A mediates antigen uptake and (cross-)presentation by human blood BDCA3+ myeloid dendritic cells. Blood\| PubMed ID: 22234694	2012
Harnessing human plasmacytoid dendritic cells as professional APCs. Cancer immunology, immunotherapy : CII\| PubMed ID: 22294456	2012
Comparison of antibodies and carbohydrates to target vaccines to human dendritic cells via DC-SIGN. Biomaterials\| PubMed ID: 22410170	2012
Lateral mobility of individual integrin nanoclusters orchestrates the onset for leukocyte adhesion. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22411821	2012
Targeting nanoparticles to dendritic cells for immunotherapy. Methods in enzymology\| PubMed ID: 22568905	2012
Antibodies and carbohydrate ligands binding to DC-SIGN differentially modulate receptor trafficking. European journal of immunology\| PubMed ID: 22653683	2012
The modular nature of dendritic cell responses to commensal and pathogenic fungi. PloS one\| PubMed ID: 22879980	2012
Vaccination with mRNA-electroporated dendritic cells induces robust tumor antigen-specific CD4+ and CD8+ T cells responses in stage III and IV melanoma patients. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 22896657	2012
Insight into the dynamics, localization and magnitude of antigen-specific immune responses by [(18)F]FLT PET imaging. Oncoimmunology\| PubMed ID: 22934268	2012
Labeling cells for in vivo tracking using (19)F MRI. Biomaterials\| PubMed ID: 22959182	2012
Human plasmacytoid dendritic cells are equipped with antigen-presenting and tumoricidal capacities. Blood\| PubMed ID: 22966165	2012
Skin-test infiltrating lymphocytes early predict clinical outcome of dendritic cell-based vaccination in metastatic melanoma. Cancer research\| PubMed ID: 23010076	2012
The neck region of the C-type lectin DC-SIGN regulates its surface spatiotemporal organization and virus-binding capacity on antigen-presenting cells. The Journal of biological chemistry\| PubMed ID: 23019323	2012
ALCAM/CD166 adhesive function is regulated by the tetraspanin CD9. Cellular and molecular life sciences : CMLS\| PubMed ID: 23052204	2013
In vivo imaging of therapy-induced anti-cancer immune responses in humans. Cellular and molecular life sciences : CMLS\| PubMed ID: 23052208	2012
Targeting CD4(+) T-helper cells improves the induction of antitumor responses in dendritic cell-based vaccination. Cancer research\| PubMed ID: 23087058	2013
In vivo tracking techniques for cellular regeneration, replacement, and redirection. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 23143090	2012
Enhancing immunogenicity and cross-reactivity of HIV-1 antigens by in vivo targeting to dendritic cells. Nanomedicine (London, England)\| PubMed ID: 23148541	2012
The tetraspanin CD37 orchestrates the α(4)β(1) integrin-Akt signaling axis and supports long-lived plasma cell survival. Science signaling\| PubMed ID: 23150881	2012
Human plasmacytoid dendritic cells efficiently cross-present exogenous Ags to CD8+ T cells despite lower Ag uptake than myeloid dendritic cell subsets. Blood\| PubMed ID: 23212525	2013
Natural human plasmacytoid dendritic cells induce antigen-specific T-cell responses in melanoma patients. Cancer research\| PubMed ID: 23345163	2013
Automated podosome identification and characterization in fluorescence microscopy images. Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada\| PubMed ID: 23347434	2013
Targeting of 111In-labeled dendritic cell human vaccines improved by reducing number of cells. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 23382117	2013
Targeting dendritic cells--why bother? Blood\| PubMed ID: 23390195	2013
The nature of activatory and tolerogenic dendritic cell-derived signal II. Frontiers in immunology\| PubMed ID: 23450201	2013
Dendritic cell-based nanovaccines for cancer immunotherapy. Current opinion in immunology\| PubMed ID: 23571027	2013
Functional OCT4-specific CD4(+) and CD8(+) T cells in healthy controls and ovarian cancer patients. Oncoimmunology\| PubMed ID: 23762805	2013
Physical limits of cell migration: control by ECM space and nuclear deformation and tuning by proteolysis and traction force. The Journal of cell biology\| PubMed ID: 23798731	2013
Naturally circulating dendritic cells to vaccinate cancer patients. Oncoimmunology\| PubMed ID: 23802086	2013
Importance of helper T-cell activation in dendritic cell-based anticancer immunotherapy. Oncoimmunology\| PubMed ID: 23894702	2013
The stem cell markers Oct4A, Nanog and c-Myc are expressed in ascites cells and tumor tissue of ovarian cancer patients. Cellular oncology (Dordrecht)\| PubMed ID: 23928726	2013
Reducing cell number improves the homing of dendritic cells to lymph nodes upon intradermal vaccination. Oncoimmunology\| PubMed ID: 24073362	2013
Targeting uptake receptors on human plasmacytoid dendritic cells triggers antigen cross-presentation and robust type I IFN secretion. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24127556	2013
Aiming to immune elimination of ovarian cancer stem cells. World journal of stem cells\| PubMed ID: 24179603	2013
Probing cellular heterogeneity in cytokine-secreting immune cells using droplet-based microfluidics. Lab on a chip\| PubMed ID: 24185478	2013
Tumoricidal activity of human dendritic cells. Trends in immunology\| PubMed ID: 24262387	2013
Ipilimumab administered to metastatic melanoma patients who progressed after dendritic cell vaccination. Oncoimmunology\| PubMed ID: 27622070	2016
Restoring immunosurveillance by dendritic cell vaccines and manipulation of the tumor microenvironment. Immunobiology\| PubMed ID: 25466585	2015
Design of a highly selective quenched activity-based probe and its application in dual color imaging studies of cathepsin S activity localization. Journal of the American Chemical Society\| PubMed ID: 25785540	2015
Intranodal vaccination with mRNA-optimized dendritic cells in metastatic melanoma patients. Oncoimmunology\| PubMed ID: 26405571	2015
Semaphorin 7A Promotes Chemokine-Driven Dendritic Cell Migration. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 26597008	2016
Effective Clinical Responses in Metastatic Melanoma Patients after Vaccination with Primary Myeloid Dendritic Cells. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 26712687	2016
Tetraspanin CD37 protects against the development of B cell lymphoma. The Journal of clinical investigation\| PubMed ID: 26784544	2016
Prophylactic vaccines are potent activators of monocyte-derived dendritic cells and drive effective anti-tumor responses in melanoma patients at the cost of toxicity. Cancer immunology, immunotherapy : CII\| PubMed ID: 26861670	2016
Proteome Based Construction of the Lymphocyte Function-Associated Antigen 1 (LFA-1) Interactome in Human Dendritic Cells. PloS one\| PubMed ID: 26889827	2016
Favorable overall survival in stage III melanoma patients after adjuvant dendritic cell vaccination. Oncoimmunology\| PubMed ID: 26942068	2016
Long-lasting multifunctional CD8 T cell responses in end-stage melanoma patients can be induced by dendritic cell vaccination. Oncoimmunology\| PubMed ID: 26942087	2016
Co-delivery of PLGA encapsulated invariant NKT cell agonist with antigenic protein induce strong T cell-mediated antitumor immune responses. Oncoimmunology\| PubMed ID: 26942088	2016
A Comparative Study of the T Cell Stimulatory and Polarizing Capacity of Human Primary Blood Dendritic Cell Subsets. Mediators of inflammation\| PubMed ID: 27057096	2016
Opportunities for immunotherapy in microsatellite instable colorectal cancer. Cancer immunology, immunotherapy : CII\| PubMed ID: 27060000	2016
Preclinical exploration of combining plasmacytoid and myeloid dendritic cell vaccination with BRAF inhibition. Journal of translational medicine\| PubMed ID: 27075584	2016
Dendritic Cell-Based Immunotherapy: State of the Art and Beyond. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 27084743	2016
T-cell Landscape in a Primary Melanoma Predicts the Survival of Patients with Metastatic Disease after Their Treatment with Dendritic Cell Vaccines. Cancer research\| PubMed ID: 27197179	2016
Immune-related Adverse Events of Dendritic Cell Vaccination Correlate With Immunologic and Clinical Outcome in Stage III and IV Melanoma Patients. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 27227325	2016
Expansion of a BDCA1+CD14+ Myeloid Cell Population in Melanoma Patients May Attenuate the Efficacy of Dendritic Cell Vaccines. Cancer research\| PubMed ID: 27325645	2016
Adjuvant Dendritic Cell Vaccination in High-Risk Uveal Melanoma. Ophthalmology\| PubMed ID: 27476772	2016
Adjuvant dendritic cell vaccination induces tumor-specific immune responses in the majority of stage III melanoma patients. Oncoimmunology\| PubMed ID: 27622047	2016
Human CD1c(+) DCs are critical cellular mediators of immune responses induced by immunogenic cell death. Oncoimmunology\| PubMed ID: 27622063	2016
Proteomics of Human Dendritic Cell Subsets Reveals Subset-Specific Surface Markers and Differential Inflammasome Function. Cell reports\| PubMed ID: 27626665	2016
Harnessing RNA sequencing for global, unbiased evaluation of two new adjuvants for dendritic-cell immunotherapy. Oncotarget\| PubMed ID: 28186996	2017
N-glycan mediated adhesion strengthening during pathogen-receptor binding revealed by cell-cell force spectroscopy. Scientific reports\| PubMed ID: 28751750	2017
Migrating into the Tumor: a Roadmap for T Cells. Trends in cancer\| PubMed ID: 29120755	2017
Eight-Color Multiplex Immunohistochemistry for Simultaneous Detection of Multiple Immune Checkpoint Molecules within the Tumor Microenvironment. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 29141863	2018
Dendritic cells in cancer immunotherapy. Nature materials\| PubMed ID: 29795222	2018
A comparative assessment of continuous production techniques to generate sub-micron size PLGA particles. International journal of pharmaceutics\| PubMed ID: 30144511	2018
C-type lectin-like receptor 2 (CLEC-2)-dependent dendritic cell migration is controlled by tetraspanin CD37. Journal of cell science\| PubMed ID: 30185523	2018
Biophysical Characterization of CD6-TCR/CD3 Interplay in T Cells. Frontiers in immunology\| PubMed ID: 30356797	2018
Injectable Biomimetic Hydrogels as Tools for Efficient T Cell Expansion and Delivery. Frontiers in immunology\| PubMed ID: 30546367	2018
Attacking Tumors From All Sides: Personalized Multiplex Vaccines to Tackle Intratumor Heterogeneity. Frontiers in immunology\| PubMed ID: 31040852	2019
ICAM3-Fc Outperforms Receptor-Specific Antibodies Targeted Nanoparticles to Dendritic Cells for Cross-Presentation. Molecules (Basel, Switzerland)\| PubMed ID: 31083610	2019
Biomaterial-Based Activation and Expansion of Tumor-Specific T Cells. Frontiers in immunology\| PubMed ID: 31130945	2019
Synthetic Semiflexible and Bioactive Brushes. Biomacromolecules\| PubMed ID: 31150222	2019
Functional diversification of hybridoma-produced antibodies by CRISPR/HDR genomic engineering. Science advances\| PubMed ID: 31489367	2019
Imaging of T-cells and their responses during anti-cancer immunotherapy. Theranostics\| PubMed ID: 31656546	2019
Microfluidics-Assisted Size Tuning and Biological Evaluation of PLGA Particles. Pharmaceutics\| PubMed ID: 31717354	2019
Blood-derived dendritic cell vaccinations induce immune responses that correlate with clinical outcome in patients with chemo-naive castration-resistant prostate cancer. Journal for immunotherapy of cancer\| PubMed ID: 31727154	2019
Intracellular Galectin-9 Controls Dendritic Cell Function by Maintaining Plasma Membrane Rigidity. iScience\| PubMed ID: 31786520	2019
Cross-talk between iNKT cells and CD8 T cells in the spleen requires the IL-4/CCL17 axis for the generation of short-lived effector cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 31796596	2019
Autologous monocyte-derived DC vaccination combined with cisplatin in stage III and IV melanoma patients: a prospective, randomized phase 2 trial. Cancer immunology, immunotherapy : CII\| PubMed ID: 31980913	2020
Multicore Liquid Perfluorocarbon-Loaded Multimodal Nanoparticles for Stable Ultrasound and F MRI Applied to In Vivo Cell Tracking. Advanced functional materials\| PubMed ID: 32132881	2019
The tumour microenvironment shapes dendritic cell plasticity in a human organotypic melanoma culture. Nature communications\| PubMed ID: 32488012	2020
Collective invasion induced by an autocrine purinergic loop through connexin-43 hemichannels. The Journal of cell biology\| PubMed ID: 32777015	2020
High Health-Related Quality of Life During Dendritic Cell Vaccination Therapy in Patients With Castration-Resistant Prostate Cancer. Frontiers in oncology\| PubMed ID: 33194595	2020
Nanovaccine administration route is critical to obtain pertinent iNKt cell help for robust anti-tumor T and B cell responses. Oncoimmunology\| PubMed ID: 33457086	2020
Dual Site-Specific Chemoenzymatic Antibody Fragment Conjugation Using CRISPR-Based Hybridoma Engineering. Bioconjugate chemistry\| PubMed ID: 33476135	2021
Human type 1 and type 2 conventional dendritic cells express indoleamine 2,3-dioxygenase 1 with functional effects on T cell priming. European journal of immunology\| PubMed ID: 33675038	2021
PLGA Nanoparticles Co-encapsulating NY-ESO-1 Peptides and IMM60 Induce Robust CD8 and CD4 T Cell and B Cell Responses. Frontiers in immunology\| PubMed ID: 33717196	2021
Semiflexible Immunobrushes Induce Enhanced T Cell Activation and Expansion. ACS applied materials & interfaces\| PubMed ID: 33797875	2021
Three distinct tolerogenic CD14 myeloid cell types to actively manage autoimmune disease: Opportunities and challenges. Journal of autoimmunity\| PubMed ID: 33901801	2021
A tipping point in cancer-immune dynamics leads to divergent immunotherapy responses and hampers biomarker discovery. Journal for immunotherapy of cancer\| PubMed ID: 34059522	2021
PLGA-based nanomedicines manufacturing: Technologies overview and challenges in industrial scale-up. International journal of pharmaceutics\| PubMed ID: 34144133	2021
Characterization of Intrinsically Radiolabeled Poly(lactic--glycolic acid) Nanoparticles for ex Vivo Autologous Cell Labeling and in Vivo Tracking. Bioconjugate chemistry\| PubMed ID: 34161070	2021
Metabolic Screening of Cytotoxic T-cell Effector Function Reveals the Role of CRAC Channels in Regulating Lethal Hit Delivery. Cancer immunology research\| PubMed ID: 34226201	2021
Cytotoxic T cells are able to efficiently eliminate cancer cells by additive cytotoxicity. Nature communications\| PubMed ID: 34471116	2021
In Vivo PET Imaging of Monocytes Labeled with [Zr]Zr-PLGA-NH Nanoparticles in Tumor and Infection Models. Cancers\| PubMed ID: 34680219	2021
Robust Antigen-Specific T Cell Activation within Injectable 3D Synthetic Nanovaccine Depots. ACS biomaterials science & engineering\| PubMed ID: 34734689	2021
Assessing the safety, tolerability and efficacy of PLGA-based immunomodulatory nanoparticles in patients with advanced NY-ESO-1-positive cancers: a first-in-human phase I open-label dose-esc... BMJ open\| PubMed ID: 34848513	2021
Multiscale imaging of therapeutic anti-PD-L1 antibody localization using molecularly defined imaging agents. Journal of nanobiotechnology\| PubMed ID: 35109860	2022
Efficient targeting of NY-ESO-1 tumor antigen to human cDC1s by lymphotactin results in cross-presentation and antigen-specific T cell expansion. Journal for immunotherapy of cancer\| PubMed ID: 35428705	2022
Design of triphasic poly(lactic--glycolic acid) nanoparticles containing a perfluorocarbon phase for biomedical applications. RSC advances\| PubMed ID: 35540375	2018
Paired primary and metastatic lesions of patients with ipilimumab-treated melanoma: high variation in lymphocyte infiltration and HLA-ABC expression whereas tumor mutational load is similar ... Journal for immunotherapy of cancer\| PubMed ID: 35550553	2022
Correction to: Multiscale imaging of therapeutic anti-PD-L1 antibody localization using molecularly defined imaging agents Iris. Journal of nanobiotechnology\| PubMed ID: 35568872	2022
Regulatory T Cell Depletion Using a CRISPR Fc-Optimized CD25 Antibody. International journal of molecular sciences\| PubMed ID: 35955841	2022
Tumor microenvironment shows an immunological abscopal effect in patients with NSCLC treated with pembrolizumab-radiotherapy combination. Journal for immunotherapy of cancer\| PubMed ID: 36252995	2022