Sofia Lachiondo-Ortega

Liver Disease


Sofía Lachiondo-Ortega
Early Stage Researcher

Sofia Lachiondo-Ortega obtained her undergraduate degree in Biochemistry and Molecular Biology from the University of the Basque Country (Spain), and studied a MRes in Drug Discovery and Development at Imperial College London (United Kingdom).

During her BSc thesis, SofIa participated in the study of the role of the mitochondrial protein MCJ in the development of non-alcoholic fatty liver disease (NAFLD). As a postgraduate, she focused on the development and validation of a novel chemical probe for the study of a deubiquitinating enzyme with pathological implications in liver fibrosis.

Her interest in posttranslational modifications within liver disease motivated her to start her PhD at the CIC bioGUNE (Spain) in the Liver Disease Lab during 2019, enabling her order to elucidate the impact of SUMOylation in hepatocellular carcinoma.


SUMO-Binding Entities (SUBEs) as Tools for the Enrichment, Isolation, Identification, and Characterization of the SUMO Proteome in Liver Cancer

1Liver Disease and Liver Metabolism Lab, CIC bioGUNE, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), 2Proteomics Platforms, CIC bioGUNE, ProteoRED-ISCIII, CIBERehd, 3Advanced Technology Institute in Life Sciences (ITAV)-CNRS-IPBS, UbiCARE

JoVE 60098