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HIGH SCHOOL

Biology

Science Experiments

Basic Biology

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Biology II: Mouse, Zebrafish, and Chick

Tracking Mouse DNA Inherited Traits

Description

Mouse DNA tracking helps scientists follow inherited traits across generations. Because mice share a high degree of genetic similarity with humans, they are a common model for studying how genes affect biology. Researchers often change a gene sequence and then look for the phenotype, or visible effect of that change, in the ...

Transcript

基因分型是检测某特定DNA序列在一个生物基因组中是否存在的过程。

因为基因可影响小鼠的表型,能够探测单个小鼠的基因组成,或称"基因型",是将某表型归因于一个特定基因的关键。本短片将探讨小鼠遗传学,演示基因分型方法的关键步骤,并解释如何分析基于PCR的基因分型结果。

为了了解研究人员在做小鼠基因分型时寻找的是什么,让我们回顾一下一些常见的小鼠遗传学操作。

要研究一个基因,科学家们经常通过改变其基因序列破坏其功能。

然而,小鼠是二倍体,所以任何基因它们都有两个拷贝。由于大多数基因只需要一个正常拷贝就能有功能,所以我们在研究表型前必须培育两个基因拷贝都...

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