Biological Pest Control

Biological pest control is the management of harmful insects, weeds, and other pests through living organisms or their naturally derived products rather than primarily synthetic chemicals. It works when predators, parasitoids, pathogens, or microbial compounds disrupt pest feeding, development, reproduction, or survival; for example, Bacillus thuringiensis produces insecticidal proteins that bind to receptors in susceptible insect larvae and damage the gut. Biochemical principles help explain host specificity, toxin activity, signaling, and resistance development. These approaches support integrated pest management by reducing pesticide residues, protecting beneficial organisms when carefully applied, and providing more sustainable options for agriculture, forestry, and public health.

Biological Pest Control - Related Videos

Research

JoVE Journal - Bioengineering
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Establishing Fungal Entomopathogens as Endophytes: Towards Endophytic Biological Control

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Cited by 197 •

2013

This protocol demonstrates two inoculation methods to introduce the fungal entomopathogen Beauveria bassiana as an endophyte in the common bean (Phaseolus vulgaris), in preparation for subsequent evaluations of endophytic biological control.

Education

JoVE Core - Microbiology

Biological Methods for Microbial Control

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2025

Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...

Research

JoVE Journal - Environment
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Procedures of Laboratory Fumigation for Pest Control with Nitric Oxide Gas

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Cited by 12 •

2017

This paper describes nitric oxide (NO) fumigation protocols for postharvest pest control. Fumigation chambers are flushed with nitrogen (N2) to establish ultralow oxygen conditions before NO is injected. At the end, chambers are flushed with N2 to dilute NO before exposing products to ambient air to prevent exposure to NO2.

Application of Two-spotted Spider Mite Tetranychus urticae for Plant-pest Interaction Studies

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Cited by 61 •

2014

Protocols for efficient preparation of homogenous samples of spider mites, infestation of experimental plants, and assessment of plant damage, as required for studies of plant-pest interaction were developed.

Delivery of Nucleic Acids through Embryo Microinjection in the Worldwide Agricultural Pest Insect, Ceratitis capitata

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Cited by 7 •

2016

The Mediterranean fruit fly (medfly) Ceratitis capitata (Diptera: Tephritidae) is a worldwide pest of agriculture. A deeper understanding of its biology is key to control medfly populations and thus reduce economic impact. Embryo microinjection is a fundamental tool allowing both germ-line transformation and reverse genetics studies in this species.

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