Core Cladding Flow
Core Cladding Flow - Related Videos
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The Nucleosome Core Particle
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Nucleosomes are the DNA-histone complex, where the DNA strand is wound around the histone core. The histone core is an octamer containing two copies of H2A, H2B, H3, and H4 histone proteins. The paradox Nucleosomes, paradoxically, perform two opposite functions simultaneously. On the one hand, their main responsibility is to protect the delicate DNA strands from physical damage and help achieve a higher compaction ratio. While on the other hand, they must allow polymerase enzymes to access DNA...
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This paper presents a protocol for the fabrication of a conduction micropump using symmetric planar electrodes on flame-retardant glass-reinforced epoxy (FR-4) copper-clad laminate (CCL) to test the influence of chamber dimensions on the performance of a conduction micropump.
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Flow Cytometry Purification of Mouse Meiotic Cells
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02:23
Visualizing the Effect of pH on Solubilization of the Influenza A Viral Core
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Source: Stauffer, S. et al., In Vitro Disassembly of Influenza A Virus Capsids by Gradient Centrifugation. J. Vis. Exp. (2016)This video demonstrates the effect of pH on the solubilization of influenza A viral cores. Gel electrophoresis and protein staining reveal the progressive disassembly of the core structure under acidic conditions.
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A Protocol for Collecting and Constructing Soil Core Lysimeters
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FAQs
The cladding stream shapes the interface around the central core while the two fluids move in parallel under predominantly laminar conditions. Because this arrangement avoids turbulent mixing, the surrounding phase can focus, sheath, or encapsulate the core. That control helps organize materials into structures with defined dimensions and composition.
Predominantly laminar movement keeps the core and cladding phases arranged as parallel streams rather than promoting turbulent intermixing. Maintaining this organized interface is important when researchers need the surrounding fluid to remain spatially associated with the core. The result is greater control over material organization and the structure formed downstream.
The key feature is the spatial relationship between the central core and the surrounding cladding phase. Their organized parallel movement allows the cladding to perform different roles, including narrowing or focusing the core, surrounding it as a sheath, or enclosing it through encapsulation. These roles determine how the resulting material is organized.
The workflow begins by introducing the core and cladding fluids separately into a microfluidic device. The central stream then travels within the surrounding stream, with both phases moving in parallel under predominantly laminar conditions. This configuration establishes a controlled interface that can be used to generate organized droplets, fibers, particles, or cell-containing structures.
In bioengineering, the configuration supports biomaterial fabrication, cell encapsulation, tissue engineering, and microscale delivery systems. Its value comes from controlling how materials or cells are positioned within a surrounding phase. That organization can help produce structured outputs with controlled dimensions and composition for different research and development goals.
Researchers can use the controlled core-cladding arrangement to form uniform droplets, fibers, particles, and cell-containing structures. The method also provides control over the dimensions and composition of these outputs. Such outcomes are relevant when bioengineering experiments require reproducible material organization, encapsulated cells, or microscale structures for delivery and tissue-related work.