Electrospinning With Polymer Melts

Electrospinning with polymer melts is a fiber-production technique that forms continuous, ultrafine polymer fibers without using a solvent, making it valuable for engineering materials with controlled structure and surface area. In this process, heat lowers the polymer’s viscosity, while a high-voltage electric field draws a charged melt from a nozzle; as the jet stretches and cools, it deposits as a nonwoven fiber mat. In bioengineering, these melt-spun scaffolds can support tissue engineering, filtration, and controlled drug delivery while avoiding solvent residues. Adjusting temperature, voltage, flow rate, and collector design helps control fiber diameter, alignment, and porosity.

Electrospinning With Polymer Melts - Related Videos

Research

JoVE Journal - Bioengineering

Melt Electrospinning Writing of Three-dimensional Poly(ε-caprolactone) Scaffolds with Controllable Morphologies for Tissue Engineering Applications

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Cited by 56 •

2017

This protocol serves as a comprehensive guideline to fabricate scaffolds via electrospinning with polymer melts in a direct writing mode. We systematically outline the process and define the appropriate parameter settings for achieving targeted scaffold architectures.

Education

JoVE Science Education - Engineering

Electrospinning of Silk Biomaterials

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2023

Silk fibers have been processed and used to create fabrics and threads for centuries. However, the solubilizing of silk fibers, thereby turning it into a versatile pre-polymer solution is a much newer technology. Solubilized silk can be processed in many different ways to create a biocompatible material with controllable mechanical properties. This video introduces the processing of silk from silk worm cocoons, and shows how the silk solution can be used to create a fiber mat via...

Synthesis of Cyclic Polymers and Characterization of Their Diffusive Motion in the Melt State at the Single Molecule Level

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2016

A protocol for the synthesis and characterization of diffusive motion of cyclic polymers at the single molecule level is presented.

Electrospinning Fibrous Polymer Scaffolds for Tissue Engineering and Cell Culture

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Cited by 38 •

2009

The process of electrospinning polymers for tissue engineering and cell culture is addressed in this article. Specifically, the electrospinning of photoreactive macromers with additional processing capabilities of photopatterning and multi-polymer electrospinning is described.

Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents

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Cited by 10 •

2016

In the protocol, we present a method to manufacture a small caliber stent-graft by sandwiching a balloon expandable stent between two electrospun nanofibrous polyurethane layers.

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