Gelatin Fiber
Gelatin Fiber - Related Videos
09:11
Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release
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Cited by 10 •
2016
We present a facile method to fabricate a biodegradable gelatin-based drug release platform that is magneto-thermally responsive. This was achieved by incorporating superparamagnetic iron oxide nanoparticles and poly(N-isopropylacrylamide-co-acrylamide) within a spherical gelatin micro-network crosslinked by genipin, in conjunction with an alternating magnetic field application system.
08:28
Microfluidic Dry-spinning and Characterization of Regenerated Silk Fibroin Fibers
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Cited by 6 •
2017
A protocol for the microfluidic spinning and microstructure characterization of regenerated silk fibroin monofilament is presented.
03:55
In Vivo Single-Fiber Recording of Sciatic Nerve C-Fibers in Rats
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2025
This video demonstrates a single-fiber recording of C-fiber nerve conduction in rats. An anesthetized rat is incised to expose the sciatic nerve, which provides sensory and motor supply to the lower limbs. The individual C-fibers are then exposed. Electrical stimulation is provided using stimulus electrodes implanted in the foot, and a response is recorded from a single nerve fiber.
07:33
A Novel Culture Model for Human Pluripotent Stem Cell Propagation on Gelatin in Placenta-conditioned Media
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Cited by 5 •
2015
This protocol provides a simple and efficient way to propagate human pluripotent stem cells (hPSCs) using only conditioned media derived from the human placenta in a gelatin-coated dish without additional exogenous supplementation or hPSC-specific synthetic substrata.
02:58
Immunohistochemical Staining of Nerve Fibers in the Nucleus Basalis of Meyner of the Mouse Brain
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2025
This video demonstrates the immunohistochemical staining of cholinergic fibers in the nucleus basalis of the Meynert region of mouse brain sections. Sections are blocked and treated with primary against choline acetyltransferase, followed by biotinylated secondary antibodies. Avidin-biotin-peroxidase complexes are added, which bind to secondary antibodies, followed by the chromogenic substrate. Sections are then dehydrated and mounted before visualizing under the microscope.
FAQs
An electric field draws a gelatin-containing solution into thin fibers, and the resulting mat is porous rather than a compact film. This process allows fiber diameter and surface area to be tuned, giving researchers ways to adjust the material’s physical architecture for bioengineering studies. The architecture creates a structured environment in which cells can be supported.
Crosslinking improves the stability of gelatin fibers in aqueous environments, where maintaining the material’s intended form is important. This added stability helps researchers consider gelatin-based mats for bioengineering settings that involve water-based conditions. In practice, crosslinking connects the protein-based material’s biological utility with the structural persistence needed for scaffold-oriented research.
Their resemblance to aspects of the extracellular matrix gives gelatin fibers a biologically relevant structure for cell-based applications. This context can support cell attachment, growth, and tissue development, which are central outcomes in tissue engineering. Consequently, the material is not selected only for its fibrous form; its protein-derived character also contributes to its research value.
A supported workflow begins with a gelatin-containing solution, followed by applying an electric field that draws the solution into thin fibers. The collected fibers form a porous mat, after which crosslinking may be used to improve stability in aqueous environments. This sequence links processing conditions to the mat’s architecture and suitability for bioengineering applications.
Gelatin fiber materials are used as scaffolds for tissue engineering, wound-healing materials, and platforms for controlled drug delivery. These applications draw on different aspects of the same material: its structure can support cells, its protein-based nature is relevant to healing-oriented studies, and its fibrous format provides a platform for delivery research. Together, they place the material across several bioengineering goals.
Gelatin fibers can serve as platforms for controlled drug delivery, extending their use beyond cell-supporting scaffolds. Their fibrous mats offer a defined material format in which researchers can investigate delivery-oriented designs, while fiber diameter, surface area, and overall architecture can be tuned during processing. This makes the technique relevant when material structure is part of the delivery strategy.