Peg Microgels

PEG microgels are microscale, water-swollen particles made from crosslinked polyethylene glycol (PEG), a material valued in bioengineering for its tunable chemistry and compatibility with biological systems. Their polymer networks absorb water and can be engineered to control particle size, stiffness, porosity, degradation, and the presentation of biochemical cues, while functional groups support further modification or cargo loading. These properties make PEG microgels useful as carriers for drugs and proteins, scaffolds for cell culture and tissue engineering, and building blocks for injectable or assembled biomaterials. By linking microscale structure to cell and molecular behavior, they support the design of more precise therapeutic and regenerative systems.

Peg Microgels - Related Videos

Research

JoVE Journal - Neuroscience
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Electrophysiology of Scorpion Peg Sensilla

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Cited by 4 •

2011

This article describes an electrophysiological method for isolating chemical stimulation to individual sensilla via extracellular, tip-recordings under mineral oil.

Research

JoVE Journal - Chemistry

Controlled Synthesis and Fluorescence Tracking of Highly Uniform Poly(N-isopropylacrylamide) Microgels

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Cited by 5 •

2016

Non-stirred precipitation polymerization provides a rapid, reproducible prototyping approach to the synthesis of stimuli-sensitive poly(N-isopropylacrylamide) microgels of narrow size distribution. In this protocol synthesis, light scattering characterization and single particle fluorescence tracking of these microgels in a wide-field microscopy setup are demonstrated.

Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release

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Cited by 10 •

2016

We present a facile method to fabricate a biodegradable gelatin-based drug release platform that is magneto-thermally responsive. This was achieved by incorporating superparamagnetic iron oxide nanoparticles and poly(N-isopropylacrylamide-co-acrylamide) within a spherical gelatin micro-network crosslinked by genipin, in conjunction with an alternating magnetic field application system.

A Peg Plate Biofilm Assay for Screening Antibacterial Agents

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2025

This video demonstrates an assay for screening antimicrobial compounds that efficiently eliminate biofilms using a peg-plate. The methodology monitors the biofilm's metabolic state after treatment with antimicrobial compounds, facilitating the determination of the minimum biofilm eradication concentration.

Magnetic and Thermal-sensitive Poly(N-isopropylacrylamide)-based Microgels for Magnetically Triggered Controlled Release

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Cited by 9 •

2017

This manuscript describes the preparation of magnetic and thermal-sensitive microgels via a temperature-induced emulsion without chemical reaction. These sensitive microgels were synthesized by mixing poly(N-isopropylacrylamide) (PNIPAAm), polyethylenimine (PEI) and Fe3O4-NH2 nanoparticles for the potential use in magnetically and thermally triggered drug-release.

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