Splenectomy Procedure

Splenectomy is the surgical removal of the spleen, an organ that filters blood, supports immune responses, and stores platelets; it may be performed to treat disease or obtain tissue for investigation. During the procedure, surgeons remove the spleen through an open or minimally invasive approach, then control blood vessels and assess nearby structures to limit bleeding and other complications. In cancer research, splenectomy procedures can provide specimens for analyzing tumor involvement, immune-cell interactions, and blood-related abnormalities, while clinical studies use them to evaluate how loss of splenic function affects infection risk, inflammation, and treatment outcomes. Careful patient selection and postoperative monitoring are essential.

Splenectomy Procedure - Related Videos

Research

JoVE Journal - Medicine
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Robot-assisted Partial Splenectomy

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2026

This protocol describes a robot-assisted partial splenectomy for a benign splenic tumor. The robotic approach optimizes spleen preservation by enhancing surgical precision, minimizing blood loss, and improving postoperative outcomes. Key surgical steps include meticulous splenic hilum dissection, selective vascular ligation, intraoperative ultrasonography, and controlled parenchymal transection.

Research

JoVE Journal - Medicine

Application of Microwave Ablation in Laparoscopic Partial Splenectomy

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Cited by 2 •

2024

The use of laparoscopic partial splenectomy has been limited due to the high risk of bleeding during surgery. Therefore, we introduce a laparoscopic method combined with microwave ablation to solve the problem of intraoperative bleeding.

Education

JoVE Core - Social Psychology

Blind Procedures

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2020

Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which child was...

Laparoscopic Splenectomy with Pericardial Devascularization for Hypersplenism and Esophageal Variceal Hemorrhage Due to Portal Hypertension

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Cited by 2 •

2024

With the rapid advancement of laparoscopic techniques, the minimally invasive benefits of laparoscopic splenectomy combined with pericardial devascularization have become increasingly evident. In this context, we present a protocol for performing laparoscopic splenectomy alongside pericardial devascularization to treat hypersplenism and esophageal variceal hemorrhage resulting from portal hypertension.

Basic Care Procedures

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2016

Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN Mice and rats account for a large proportion of the animals used in biomedical research. Ensuring their welfare is both an ethical responsibility and essential for scientific validity. There are general procedures that apply to the majority of these mice and rats, but some of the animals, such as the immunocompromised ones, require additional steps to be taken to sustain them for...

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