Stone Passage

Stone passage is the movement of a urinary stone from the kidney through the ureter and bladder before it leaves the body, an important clinical event because obstruction can cause severe pain and impair urine flow. Passage occurs when ureteral smooth-muscle contractions and urine movement propel the stone downward; its size, shape, and location influence whether it passes spontaneously or becomes lodged. Clinicians evaluate symptoms and use imaging to assess stone position, urinary obstruction, and complications, guiding observation, pain management, or procedures that fragment or remove the stone. Understanding stone passage supports timely treatment and helps reduce kidney injury and recurrent urinary tract problems.

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Education

JoVE Science Education - Basic Biology

Passaging Cells

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2023

Cell lines are frequently used in biomedical experiments, as they allow rapid culture and expansion of cell types for experimental analysis. Cell lines are cultured under similar conditions when compared to freshly-isolated, or primary, cells, but with some basic important differences: (i) cell lines require their own specific growth factor cocktails and (ii) their growth must be more closely monitored than primary cells, as the mutations that allow them to be grown indefinitely also can...

Research

JoVE Journal - Biology

Passaging Human Neural Stem Cells

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Cited by 8 •

2007

The ability to manipulate human neural stem/precursor cells (hNSPCs) in vitro allows to investigate their utility as cell transplants for therapeutic purposes and to explore human neural development. This protocol presents a method of culturing and passaging hNSPCs in hopes of increasing reproducibility of human stem cell research.

Quarrying of Stone

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2024

Quarrying is the process of extracting stone from a quarry, where specialized techniques are employed to remove large blocks of stone safely and efficiently. This process can involve controlled explosions or more precision-oriented methods such as cutting and drilling. One common method involves using a diamond belt saw to cut large blocks from the quarry face. These blocks can be about 50 feet long and 12 feet high. After the initial vertical cut, drilling is performed at the base of the block.

Stone Masonry

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2024

Stone masonry is a construction technique that uses individual stones to build structures and can be categorized into two main types: rubble and ashlar. Rubble masonry uses uneven, naturally shaped stones such as river rocks or fragments from quarries. This method often requires the mason to select and possibly shape each stone to fit the designated space, ensuring a proper build, even with irregular stone sizes and shapes. Ashlar masonry, on the other hand, employs uniformly cut stones that...

Types of Building Stone

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2024

Building stones, essential materials for construction, are extracted from natural rock deposits and processed into specific forms and dimensions suitable for various building applications. These stones are broadly classified into three types based on their geological formation: igneous, sedimentary, and metamorphic. Igneous rocks are formed from the solidification of magma or lava. An example is granite, known for its durability and resistance to weathering, making it ideal for parts of...

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