Ventilator Associated Pneumonia
Ventilator Associated Pneumonia - Related Videos
04:32
Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
0 Views •
Cited by 35 •
2018
Infectious pneumonia is among the most common infections in human. An appropriate in vivo model is critical for understanding disease pathogenesis and testing the efficacy of novel therapeutics. With this murine oropharyngeal aspiration pneumonia model, one can examine the pathogenesis and new treatments against these deadly infections.
09:17
A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii
0 Views •
Cited by 17 •
2017
A method for establishing lung infections in immunocompetent rodents is described. With proficiency, this method can be performed quickly and easily to induce stable infection with many isolates of S. pneumoniae, H. influenzae, P. aeruginosa, K. pneumoniae and A. baumannii.
13:27
Osteopathic Manipulative Treatment as a Useful Adjunctive Tool for Pneumonia
0 Views •
Cited by 50 •
2014
Pneumonia is one of the top ten leading causes of death in the U.S. Osteopathic manipulative techniques (OMT) may be utilized as an adjunctive therapy in the treatment of pneumonia to enhance biomechanical and immune function; and ultimately, to reduce hospital stay, duration of antibiotics, incidence of respiratory failure, and mortality. In this video-article, we will review randomized controlled studies on the use of OMT in pneumonia patients, as well as demonstrate specific hands-on...
01:23
Mechanical Ventilation II: Invasive Ventilation
0 Views •
2025
Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators. Negative-Pressure Ventilators Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
03:14
Microaerobic Fermentation of Bamboo Hydrolysate by Klebsiella pneumoniae
0 Views •
2025
Source: Wei, D., et al., Production of Chemicals by Klebsiella pneumoniae Using Bamboo Hydrolysate as Feedstock. J. Vis. Exp. (2017)This video demonstrates the microbial conversion of bamboo-derived sugars into 2,3-butanediol by culturing Klebsiella pneumoniae in a hydrolysate-based medium under microaerobic and mildly acidic conditions.
FAQs
Microaspiration is the central route described for Ventilator Associated Pneumonia: bacteria originating in the mouth or stomach can pass around the endotracheal tube and reach the lower respiratory tract. The tube can therefore provide a pathway for contaminated material when airway protection is compromised. This mechanism makes limiting aspiration-related contamination an important prevention goal.
Critical illness and mechanical ventilation can weaken normal airway defenses, reducing the respiratory tract’s ability to prevent harmful material from reaching the lungs. At the same time, bacteria from the mouth or stomach may be introduced through microaspiration around the endotracheal tube. These factors work together, increasing vulnerability to lower respiratory tract infection during intensive care.
Evaluation combines respiratory findings, imaging, and microbiological testing rather than relying on one type of evidence alone. Respiratory assessment identifies relevant clinical changes, imaging examines the lungs, and microbiological testing helps characterize the infectious process. Together, these sources provide information that clinicians can use when deciding how to manage a suspected infection.
Oral care, elevation of the head of the bed, and minimizing unnecessary ventilation address different contributors to risk. Oral care targets the bacterial reservoir, while head-of-bed elevation may help reduce movement of contaminated material toward the lower airway. Avoiding ventilation that is no longer needed limits continued exposure to the conditions associated with infection.
Microbiological testing contributes evidence that complements respiratory findings and imaging. By helping clinicians assess the infectious process alongside the patient’s clinical and radiographic information, testing supports treatment decisions. This integrated approach is relevant to antimicrobial stewardship because it connects diagnostic evaluation with more informed use of antimicrobial therapy in critically ill patients.
Preventing VAP matters because the condition can prolong hospitalization and worsen patient outcomes. Measures that support oral hygiene, appropriate positioning, and avoidance of unnecessary ventilation address preventable contributors while patients are critically ill. In clinical practice, combining these measures with timely evaluation and careful antimicrobial decisions supports patient safety and more effective intensive care.